Abstract
Objective To evaluate the reliability and validity of a food-frequency questionnaire (FFQ) and database designed to quantify phytoestrogen consumption.
Methods This study included 195 members of the California Teachers Study (CTS) cohort who, over a 10-month period, completed four 24-h dietary recalls, a pre- and post-study FFQ, and provided two 24-h urine specimens. Participants (n=106) in a parallel study (and 18 women who dropped out of the long-term study) completed a single recall and FFQ, and provided one 24-h urine specimen. Urinary phytoestrogens were determined using liquid chromatography–mass spectrometry. Reliability and validity were evaluated using Shrout–Fleiss intraclass correlations and energy-adjusted deattenuated Pearson correlations, respectively.
Results Correlations reflecting the reproducibility of the FFQ phytoestrogen assessment ranged from 0.67 to 0.81. Validity correlations (FFQ compared to dietary recalls) ranged from 0.67 to 0.79 for the major phytoestrogenic compounds (i.e., daidzein, genistein, and secoisolariciresinol) and 0.43 to 0.54 for the less common compounds. Compared to urinary levels, validity correlations ranged from 0.41 to 0.55 for the isoflavones and 0.16 to 0.21 for total lignans.
Conclusion Our isoflavone assessment is reproducible, valid, and an excellent tool for evaluating the relationship with disease risk in non-Asian populations. Further research is needed before these tools can accurately be used to assess lignan consumption.
Similar content being viewed by others
References
PL Horn-Ross S Barnes M Lee et al. (2000) ArticleTitleAssessing phytoestrogen exposure in epidemiologic studies: development of a database (United States) Cancer Causes Control 11 289–298 Occurrence Handle1:STN:280:DC%2BD3cvpt1eqtA%3D%3D Occurrence Handle10843440
H Adlercreutz W Mazur (1997) ArticleTitlePhyto-oestrogens and Western diseases Ann Med 29 95–120 Occurrence Handle1:CAS:528:DyaK2sXlt1Sltrs%3D Occurrence Handle9187225
PL Horn-Ross M Lee EM John J Koo (2000) ArticleTitleSources of phytoestrogen exposure among non-Asian women in California, USA Cancer Causes Control 11 299–302 Occurrence Handle1:STN:280:DC%2BD3cvpt1eqtQ%3D%3D Occurrence Handle10843441
PC Pillow CM Duphorne S Chang et al. (1999) ArticleTitleDevelopment of a database for assessing dietary phytoestrogen intake Nutr Cancer 33 3–19 Occurrence Handle1:CAS:528:DyaK1MXivFSrtbw%3D Occurrence Handle10227038
K Reinli G Block (1996) ArticleTitlePhytoestrogen content of foods – a compendium of literature values Nutr Cancer 26 123–148 Occurrence Handle1:CAS:528:DyaK28XlvFaksrY%3D Occurrence Handle8875551
USDA – Iowa State University Isoflavone database. www.nal. usda.gov/fnic/foodcomp/Data/isoglav.html.
L Bernstein H Anton-Culver D Deapen et al. (2002) ArticleTitleHigh breast cancer rates among California teachers: results from the California Teachers Study Cohort Cancer Causes Control 13 625–635 Occurrence Handle12296510 Occurrence Handle10.1023/A:1019552126105
G Block AM Hartman CM Dresser MD Carroll J Gannon L Gardner (1986) ArticleTitleA data-based approach to diet questionnaire design and testing Am J Epidemiol 124 453–469 Occurrence Handle1:STN:280:BimB1M3pt1M%3D Occurrence Handle3740045
G Block M Woods A Potosky C Clifford (1990) ArticleTitleValidation of a self-administered diet history questionnaire using multiple diet records J Clin Epidemiol 43 1327–1335 Occurrence Handle1:STN:280:By6D2szhsF0%3D Occurrence Handle2254769 Occurrence Handle10.1016/0895-4356(90)90099-B
PL Horn-Ross (2001) ArticleTitleAssessing phytoestrogen exposure via a food-frequency questionnaire Cancer Causes and Control 12 477–478 Occurrence Handle1:STN:280:DC%2BD3MvpslSjuw%3D%3D Occurrence Handle11545462 Occurrence Handle10.1023/A:1011257729422
J Kelsey W Thompson A Evans (1986) Methods in Observational Epidemiology Oxford University Press New York
P Shrout J Fleiss (1979) ArticleTitleIntraclass correlations: uses in assessing rater reliability Psychol Bull 86 420–428
WC Willett (1998) Nutritional Epidemiology Oxford University Press New York
DO Stram JH Hankin LR Wilkens et al. (2000) ArticleTitleCalibration of the dietary questionnaire for a multiethnic cohort in Hawaii and Los Angeles Am J Epidemiol 151 358–570 Occurrence Handle1:STN:280:DC%2BD3c7lvVWnsw%3D%3D Occurrence Handle10695594
MH Huang GG Harrison MM Mohamed et al. (2000) ArticleTitleAssessing the accuracy of a food frequency questionnaire for estimating usual intake of phytoestrogens Nutr Cancer 37 145–154 Occurrence Handle1:STN:280:DC%2BD3Mrks1Ciuw%3D%3D Occurrence Handle11142086
G Maskarinec S Singh L Meng AA Franke (1998) ArticleTitleDietary soy intake and urinary isoflavone excretion among women from a multiethnic population Cancer Epidemiol Biomarkers Prev 7 613–619 Occurrence Handle1:CAS:528:DyaK1cXkvVagu7g%3D Occurrence Handle9681530
JW Lampe (2003) ArticleTitleIsoflavonoid and lignan phytoestrogens as dietary biomarkers J Nutr 133 956S–964S Occurrence Handle1:CAS:528:DC%2BD3sXhvFylt7k%3D Occurrence Handle12612182
C Atkinson HE Skor ED Fitzgibbons et al. (2002) ArticleTitleOvernight urinary isoflavone excretion in a population of women living in the United States, and its relationship to isoflavone intake Cancer Epidemiol Biomarkers Prev 11 253–260 Occurrence Handle1:CAS:528:DC%2BD38XivFyhsrg%3D Occurrence Handle11895874
CL Frankenfeld RE Patterson NK Horner et al. (2003) ArticleTitleValidation of a soy food-frequency questionnaire and evaluation of correlates of plasma isoflavone concentrations in postmenopausal women Am J Clin Nutr 77 674–680 Occurrence Handle1:CAS:528:DC%2BD3sXnsVSrurk%3D Occurrence Handle12600860
Z Chen W Zheng LJ Custer et al. (1999) ArticleTitleUsual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in Shanghai Nutr Cancer 33 82–87 Occurrence Handle1:STN:280:DyaK1M3ktlKgtw%3D%3D Occurrence Handle10227048
Y Arai M Uehara Y Sato et al. (2000) ArticleTitleComparison of isoflavones among dietary intake, plasma concentration and urinary excretion for accurate estimation of phytoestrogen intake Calibration of the dietary questionnaire for a multiethnic cohort in Hawaii and Los Angeles J Epidemiol 10 127–135 Occurrence Handle1:STN:280:DC%2BD3c3ktVGjtA%3D%3D Occurrence Handle10778038
S Heinonen T Nurmi K Liukkonen et al. (2001) ArticleTitleIn vitro etabolism of plant lignans: new precursors of mammalian lignans enterolactone and enterodiol J Agric Food Chem 49 3178–3186 Occurrence Handle1:CAS:528:DC%2BD3MXktFOnu7c%3D Occurrence Handle11453749 Occurrence Handle10.1021/jf010038a
LU Thompson P Robb M Serraino F Cheung (1991) ArticleTitleMammalian lignan production from various foods Nutr Cancer 16 43–52 Occurrence Handle1:CAS:528:DyaK38Xht1Onu74%3D Occurrence Handle1656395
KD Setchell NM Brown P Desai et al. (2001) ArticleTitleBioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements J Nutr 131 1362S–1375S Occurrence Handle1:CAS:528:DC%2BD3MXjsl2itb0%3D Occurrence Handle11285356
Acknowledgements
The authors would like to thank the CTS Steering Committee who are responsible for the resource within which this substudy was conducted: Hoda Anton-Culver, Leslie Bernstein, Dennis Deapen, Harvey Mohrenweiser, David Peel, Rich Pinder, David M. Purdie, Ronald K. Ross, Daniel O. Stram, Dee W. West, William E. Wright, and Argyrious Ziogas; the following people who provided technical or administrative support: Mia Cruz, Kristi Jogis, Lorraine Lindow, Diana Lee, Kristina Rickmond, Amy Shiau, Erin Silva, Jan Stewart, and Orawan Takaki; and all the participants who donated their time to this intensive study. This research was supported by grant R01 CA77398 and cooperative agreement U01 CA81789 from the National Cancer Institute and contract 97-10500 from the California Cancer Research Fund. The mass spectrometer used in this study was provided by funds from a NCRR Shared Instrumentation Award (S10 RR06487) and institutional funds from the University of Alabama at Birmingham. Operational support for the Mass Spectrometry Shared Facility came from a National Cancer Institute Core Support grant to the UAB Comprehensive Cancer Center (P30 CA-13148).
Author information
Authors and Affiliations
Corresponding author
Additional information
All work was performed at the Northern California Cancer Center with the exception of the laboratory analyses which were performed at the University of Alabama, Birmingham.
Rights and permissions
About this article
Cite this article
Horn-Ross, P.L., Barnes, S., Lee, V.S. et al. Reliability and Validity of an Assessment of Usual Phytoestrogen Consumption (United States). Cancer Causes Control 17, 85–93 (2006). https://doi.org/10.1007/s10552-005-0391-6
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s10552-005-0391-6