Skip to main content

Advertisement

SpringerLink
Log in

Dietary patterns and risk of colon cancer and adenoma in a cohort of men (United States)

  • Published:
Cancer Causes & Control Aims and scope Submit manuscript

Abstract

BackgroundExamining the effects of dietary patterns on cancer risk may provide insights beyond the assessment of individual foods or nutrients. Design: In the health professionals follow-up cohort, associations between the ‘prudent’ and the ‘western’ dietary pattern and risk of colon cancer and adenomas were examined in 561 colon cancer cases and 1207 distal colon adenoma cases. Results: Higher prudent pattern scores were only weakly and non-significantly associated with decreased risk of colon cancer or distal colon adenoma (highest versus lowest quintile: colon cancer: multivariate adjusted relative risk (RR)=0.84 (95 confidence interval (CI)=0.64–1.10); p t rend=0.37; distal adenoma: multivariate odds ratio (OR)=0.88 (95 CI=0.73–1.08); p t rend=0.12). Our findings suggest a moderately increased risk of colon cancer and distal adenoma with higher western pattern scores (colon cancer: RR=1.27 (95 CI=0.96–1.69), p t rend=0.05; distal adenoma: OR=1.28 (95 CI=1.05–1.56), p t rend=0.01). Adding body mass index, which is positively related to western pattern and thus may be considered an intermediate endpoint between western pattern and colon cancer, attenuated associations somewhat but not substantially. Conclusion: Our data do not provide evidence for an appreciable inverse association between higher prudent pattern scores and risk of colon cancer or distal colon adenomas, but do support a moderate positive association between higher western pattern scores and risk of colon cancer or distal colon adenomas.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • E Giovannucci WC Willett (1994) ArticleTitleDietary factors and risk of colon cancer Ann Med 26 443–452

    Google Scholar 

  • JD Potter (1996) ArticleTitleNutrition and colorectal cancer Cancer Causes Control 7 127–146

    Google Scholar 

  • ME Martinez JR Marshall L Sechrest (1998) ArticleTitleInvited commentary: factor analysis and the search for objectivity Am J Epidemiol 148 17–19

    Google Scholar 

  • ML Slattery KM Boucher BJ Caan JD Potter KN Ma (1998) ArticleTitleEating patterns and risk of colon cancer [comment] Am J Epidemiol 148 4–16

    Google Scholar 

  • FB Hu (2002) ArticleTitleDietary pattern analysis: a new direction in nutritional epidemiology Curr Opin Lipidol 13 3–9

    Google Scholar 

  • P Terry FB Hu H Hansen A Wolk (2001) ArticleTitleProspective study of major dietary patterns and colorectal cancer risk in women Am J Epidemiol 154 1143–1149

    Google Scholar 

  • ML Slattery JD Potter KN Ma BJ Caan M Leppert W Samowitz (2000) ArticleTitleWestern diet, family history of colorectal cancer, NAT2, GSTM-1 and risk of colon cancer Cancer Causes Control 11 1–8

    Google Scholar 

  • E Randall JR Marshall J Brasure S Graham (1992) ArticleTitleDietary patterns and colon cancer in western New York Nutr Cancer 18 265–276

    Google Scholar 

  • ML Slattery (2000) ArticleTitleDiet, lifestyle, and colon cancer Seminars in Gastrointestinal Disease. 11 142–146

    Google Scholar 

  • T Fung FB Hu C Fuchs et al. (2003) ArticleTitleMajor dietary patterns and the risk of colorectal cancer in women Arch Intern Med 163 309–314

    Google Scholar 

  • TT Fung EB Rimm D Spiegelman et al. (2001) ArticleTitleAssociation between dietary patterns and plasma biomarkers of obesity and cardiovascular disease risk [comment] Am J Clin Nutr, 73 61–67

    Google Scholar 

  • FB Hu EB Rimm MJ Stampfer A Ascherio D Spiegelman WC Willett (2000) ArticleTitleProspective study of major dietary patterns and risk of coronary heart disease in men Am J Clin Nutr. 72 912–921

    Google Scholar 

  • FB Hu E Rimm SA Smith-Warner et al. (1999) ArticleTitleReproducibility and validity of dietary patterns assessed with a food-frequency questionnaire [comment] Am J Clin Nutr. 69 243–249

    Google Scholar 

  • RM Dam ParticleVan EB Rimm WC Willett MJ Stampfer FB Hu (2002) ArticleTitleDietary patterns and risk for type 2 diabetes mellitus in U.S. men [summary for patients in Ann Intern Med . 2002 Feb 5;136(3):I30; PMID: 11928740] Ann Intern Med 136 201–209

    Google Scholar 

  • S Cotton L Sharp J Little (1996) ArticleTitleThe adenoma-carcinoma sequence and prospects for the prevention of colorectal neoplasia Crit Rev Onco 7 293–342

    Google Scholar 

  • ER Fearon B Vogelstein (1990) ArticleTitleA genetic model for colorectal tumorigenesis Cell 61 759–767

    Google Scholar 

  • EB Rimm EL Giovannucci WC Willett et al. (1991) ArticleTitleProspective study of alcohol consumption and risk of coronary disease in men [see comments] Lancet 338 464–468

    Google Scholar 

  • EK Wei E Giovannucci K Wu et al. (2004) ArticleTitleComparison of risk factors for colon and rectal cancer Int J Cancer 108 433–442

    Google Scholar 

  • WC Willett MJ Stampfer (1998) Implications of total energy intake for epidemiologic analyses WC Willett (Eds) Nutritional Epidemiology Oxford University Press New York 273–301

    Google Scholar 

  • WC Willett RD Reynolds S Cottrell-Hoehner L Sampson ML Browne (1987) ArticleTitleValidation of a semi-quantitative food frequency questionnaire: comparison with a 1-year diet record J Am Diet Assoc 87 43–47

    Google Scholar 

  • EB Rimm EL Giovannucci MJ Stampfer GA Colditz LB Litin WC Willett (1992) ArticleTitleReproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals Am J Epidemiol 135 1114–1126

    Google Scholar 

  • D Feskanich EB Rimm EL Giovannucci et al. (1993) ArticleTitleReproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire J Am Diet Assoc 93 790–796

    Google Scholar 

  • JO Kim CW Mueller (1978) Factor Analysis: Statistical Methods and Practical Issues Sage Publications Inc Thousand Oaks CA

    Google Scholar 

  • WC Willett (1998) Issues in analysis and presentation of dietary data WC Willett (Eds) Nutritional Epidemiology Oxford University Press New York 321–345

    Google Scholar 

  • S Greenland KJ Rothman (1998) Introduction to stratified analysis KJ Rothman S Greenland (Eds) Modern Epidemiology Lippincott-Raven Publishers Philadelphia, PA 253–279

    Google Scholar 

  • S Greenland (1998) Introduction to regression models KJ Rothman S Greenland (Eds) Modern Epidemiology Lippincott-Raven Publishers Philadelphia, PA 359–399

    Google Scholar 

  • P Terry E Giovannucci KB Michels et al. (2001) ArticleTitleFruit, vegetables, dietary fiber, and risk of colorectal cancer J Natl Cancer Inst 93 525–533

    Google Scholar 

  • ML Slattery TD Berry J Potter B Caan (1997) ArticleTitleDiet diversity, diet composition, and risk of colon cancer (United States) Cancer Causes Control 8 872–882

    Google Scholar 

  • A Flood EM Velie N Chaterjee et al. (2002) ArticleTitleFruit and vegetable intakes and the risk of colorectal cancer in the Breast Cancer Detection Demonstration Project follow-up cohort Am J Clin Nutr 75 936–943

    Google Scholar 

  • DS Alberts ME Martinez DJ Roe et al. (2000) ArticleTitleLack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas. Phoenix Colon Cancer Prevention Physicians’ Network N Engl J Med 342 1156–1162

    Google Scholar 

  • A Schatzkin E Lanza D Corle et al. (2000) ArticleTitleLack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. Polyp Prevention Trial Study Group N Engl J Med 342 1149–1155

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, MA, 02115, Boston, USA

    Kana Wu, Frank B. Hu, Eric B. Rimm, Walter C. Willett & Edward Giovannucci

  2. Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Charles Fuchs, Eric B. Rimm, Walter C. Willett & Edward Giovannucci

  3. Division of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA

    Charles Fuchs

  4. Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA

    Frank B. Hu, Eric B. Rimm, Walter C. Willett & Edward Giovannucci

Authors
  1. Kana Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Frank B. Hu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Charles Fuchs
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Eric B. Rimm
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Walter C. Willett
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Edward Giovannucci
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kana Wu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wu, K., Hu, F.B., Fuchs, C. et al. Dietary patterns and risk of colon cancer and adenoma in a cohort of men (United States). Cancer Causes Control 15, 853–862 (2004). https://doi.org/10.1007/s10552-004-1809-2

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10552-004-1809-2

Keywords

Search

Navigation