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Contralateral prophylactic mastectomy in women with breast cancer: trends, predictors, and areas for future research

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Abstract

Recent studies have revealed increasing rates of contralateral prophylactic mastectomy (CPM) among women with unilateral early stage breast cancer. This trend has raised concerns, given the lack of evidence for a survival benefit from CPM and the relatively low risk of contralateral breast cancer for most women in this setting. In this article, we review available data regarding the value of CPM, predictors, and outcomes related to CPM, and areas for future research and potential intervention.

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Acknowledgments

Dr. Rosenberg receives funding from the National Cancer Institute (NIH 5 R25 CA057711).

Conflict of interest

The authors declare that they have no conflicts of interest.

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Authors and Affiliations

  1. Dana-Farber Cancer Institute, Brigham and Women’s Hospital, 450 Brookline Ave Boston, Boston, MA, 02215, USA

    Michaela S. Tracy, Shoshana M. Rosenberg, Laura Dominici & Ann H. Partridge

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  1. Michaela S. Tracy
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  2. Shoshana M. Rosenberg
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  3. Laura Dominici
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  4. Ann H. Partridge
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Correspondence to Ann H. Partridge.

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Tracy, M.S., Rosenberg, S.M., Dominici, L. et al. Contralateral prophylactic mastectomy in women with breast cancer: trends, predictors, and areas for future research. Breast Cancer Res Treat 140, 447–452 (2013). https://doi.org/10.1007/s10549-013-2643-6

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