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Osteonecrosis of the jaw and bevacizumab therapy

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Breast Cancer Research and Treatment Aims and scope Submit manuscript

The Original Article was published on 02 April 2010

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References

  1. Reid IR (2009) Osteonecrosis of the jaw—who gets it, and why? Bone 44(1):4–10

    Article  CAS  PubMed  Google Scholar 

  2. Aragon-Ching JB, Ning YM, Chen CC, Latham L, Guadagnini JP, Gulley JL, Arlen PM, Wright JJ, Parnes H, Figg WD, Dahut WL (2009) Higher incidence of osteonecrosis of the jaw (ONJ) in patients with metastatic castration resistant prostate cancer treated with anti-angiogenic agents. Cancer Investig 27:221–226

    Article  CAS  Google Scholar 

  3. Khosla S, Burr D, Cauley J, Dempster DW, Ebeling P, Felsenberg D, Gagel RF, Gilsanz V, Guise T, Koka S, McCauley LK, McGowan J, McKee MD, Mohla S, Pendrys DG, Raisz LG, Ruggiero SL, Shafer DM, Shum L, Silverman SL, Van Poznak CH, Watts N, Woo S-B, Shane E (2007) Bisphosphonate-associated osteonecrosis of the jaw: report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res 1479–1491

  4. Mauri D, Valachis A, Polyzos IP, Polyzos NP, Kamposioras K, Pesce LL (2009) Osteonecrosis of the jaw and use of bisphosphonates in adjuvant breast cancer treatment: a metaanalysis. Breast Cancer Res Treat 116:433–439

    Article  CAS  PubMed  Google Scholar 

  5. Kolata G (2006) Drug for bones is newly linked to jaw disease. The New York Times June 2

  6. Almazrooa SA, Woo SB (2009) Bisphosphonate and nonbisphosphonate-associated osteonecrosis of the jaw: a review. J Am Dent Assoc 140(7):864–867

    Google Scholar 

  7. Gliklich R, Wilson J (2009) Epidemiology of bisphosphonate-related osteonecrosis of the jaws: the utility of a national registry. J Oral Maxillofac Surg 67(5, Suppl):71–74

    Article  PubMed  Google Scholar 

  8. Winter MC, Holen I, Coleman RE (2008) Exploring the anti-tumour activity of bisphosphonates in early breast cancer. Cancer Treat Rev 34(5):453–475 (Aug)

    Article  CAS  PubMed  Google Scholar 

  9. Allen MR, Burr DB (2009) The pathogenesis of bisphosphonate-related osteonecrosis of the jaw: so many hypotheses, so few data. J Oral Maxillofac Surg 67(5, Suppl):61–70

    Article  PubMed  Google Scholar 

  10. Guarneri V, Miles D, Robert N, Diéras V, Glaspy J, Smith I, Thomssen C, Biganzoli L, Taran T, Conte P (2010) Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer. Breast Cancer Res Treat. doi:10.1007/s10549-010-0866-3

  11. Edwards BJ, Gounder M, McKoy JM, Boyd I, Farrugia M, Migliorati C, Marx R, Ruggiero S, Dimopoulos M, Raisch DW, Singhal S, Carson K, Obadina E, Trifilio S, West D, Mehta J, Bennett CL (2008) Pharmacovigilance and reporting oversight in US FDA fast-track process: bisphosphonates and osteonecrosis of the jaw. Lancet Oncol 9(12):1166–1172

    Article  PubMed  Google Scholar 

  12. Kyrgidis A (2010) Bisphosphonate-related osteonecrosis of the jaw in randomized clinical trials. Breast Cancer Res Treat 119:253–254

    Article  PubMed  Google Scholar 

  13. American Association of Oral and Maxillofacial Surgeons (2007) Position paper on bisphosphonate-related osteonecrosis of the jaw. J Oral Maxillofac Surg 65:369–376

    Article  Google Scholar 

  14. Vahtsevanos K, Kyrgidis A, Verrou E, Katodritou E, Triaridis S, Andreadis C, Boukovinas I, Koloutsos G, Teleioudis Z, Kitikidou K, Paraskevopoulos P, Zervas K, Antoniades K (2009) Bisphosphonate related osteonecrosis of the jaws: a longitudinal cohort study of risk factors in cancer patients. J Clin Oncol 27(32):5356–5362

    Article  CAS  PubMed  Google Scholar 

  15. McArthur HL, Estilo C, Huryn J, Williams T, Fornier M, Traina TA, Howard J, Hudis CA, Dickler MN (2008) Osteonecrosis of the jaw (ONJ) among intravenous (IV) bisphosphonate- and/or bevacizumab-treated patients (pts) at Memorial Sloan-Kettering Cancer Center (MSKCC). J Clin Oncol 26:9588

    Google Scholar 

  16. Stopeck A, Body JJ, Fujiwara Y, Lipton A, Steger GG, Viniegra M, Fan M, Braun A, Dansey R, Jun S (2009) Denosumab versus zoledronic acid for the treatment of breast cancer patients with bone metastases: results of a randomized phase 3 study. Eur J Cancer Suppl 7(3):2 (abstract 2LBA)

    Article  Google Scholar 

  17. Henry D, von Moos R, Vadhan-Raj S, Hungria V, Spencer A, Hirsh V, Wang J, Jun S, Yeh H, Dansey R (2009) A double-blind, randomized study of denosumab versus zoledronic acid for the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. Eur J Cancer Suppl 7(3):11 (abstract 20LBA)

    Article  Google Scholar 

  18. National Institute of Health Research Portfolio Online Reporting Tools http://projectreporter.nih.gov/reporter.cfm 1R03DE019684-01A1. Accessed 15 Apr 2010

  19. Van Poznak C (2006) The phenomenon of osteonecrosis of the jaw in patients with metastatic breast cancer. Cancer Investig 24:110–112

    Article  Google Scholar 

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Authors and Affiliations

  1. University of Michigan, Ann Arbor, MI, USA

    Catherine Van Poznak

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  1. Catherine Van Poznak
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Correspondence to Catherine Van Poznak.

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This is an invited commentary to article doi: 10.1007/s10549-010-0866-3.

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Van Poznak, C. Osteonecrosis of the jaw and bevacizumab therapy. Breast Cancer Res Treat 122, 189–191 (2010). https://doi.org/10.1007/s10549-010-0933-9

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  • DOI: https://doi.org/10.1007/s10549-010-0933-9

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