Abstract
The aim of this study was to assess the intensity of diagnostic testing and cancer treatment of 335 women with advanced breast cancer during their last 6 months before death between 1995 and 1998 in the Pirkanmaa and Satakunta health care districts and to compare it to the practice in earlier decades, the 1970s and 1980s. Data for 1990s material were collected from medical records in 30-day periods starting from the patient’s death backwards. In this material 46.9% of all laboratory tests and 40% of radiological tests during the last 6 months of life were made during the last 2 months prior to death. In the last month 63.9% of patients continued on endocrine therapy and 19.7% on chemotherapy. Patient symptoms and deterioration in general condition showed the appropriate point to discontinue cancer-related treatment and concentrate on palliation of symptoms to be about 2 months prior to death. Resources devoted to diagnostic investigations and treatment of cancer in terminally ill patients could be better used for their care. This would be more likely to improve patients’ quality of life and save resources.
Similar content being viewed by others
References
Payne SK, Coyne P (2002) The health economics of palliative care. Oncology 16(6):801–808
Christakis NA, Iwashyana TJ (2000) The impact of individual and market factors on the timing of initiation of hospice terminal care. Med Care 38(5):528–541
Christakis NA, Escarce JJ (1996) Survival of Medicare patients after enrolment in hospice programs. N Engl J Med 335:172–178
Christakis NA, Lamont EB (2000) Extent and determinants of error in physicians’ prognoses for terminally ill patients: prospective cohort study. BMJ 320(7233):469–473
Lamont EB, Christakis NA (2002) Physician factors in the timing of cancer patient referral to hospice palliative care. Cancer 94:2733–2737
Holli K, Hakama M (1991) Terminal stages of breast cancer: changes in clinical practice. Eur J Cancer 27(10):1338–1339
Holli K, Hakama M (1989) Treatment of the terminal stages of breast cancer. BMJ 298:13–14
Emanuel E et al (2003) Chemotherapy use among Medicare beneficiaries at the end of life. Ann Intern Med 138:639–643
Lunney JR et al (2003) Patterns of functional decline at the end of life. JAMA 289:2387–2392
Acknowledgements
The study was supported by the Medical Research Fund of Tampere University Hospital. The skilful technical assistance of Mrs Kirsi Rouhento is gratefully appreciated by the authors.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Asola, R., Huhtala, H. & Holli, K. Intensity of diagnostic and treatment activities during the end of life of patients with advanced breast cancer. Breast Cancer Res Treat 100, 77–82 (2006). https://doi.org/10.1007/s10549-006-9224-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10549-006-9224-x