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Management of Nonpalpable Breast Lesions in a Modern Functional Breast Unit

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Summary

During the last 20 years an ever increasing number of nonpalpable breast lesions (NPBL) have been identified. A cytohistological definition is required to establish the correct diagnostic classification of these lesions and the suitable therapy to be used. The Fine-Needle Aspiration Cytology (FNAC), the Advanced Breast Biopsy Instrumentation (ABBI) system or the Vacuum Assisted Core Biopsy (VACB) represent valid alternatives to the surgical excision with needle localisation. 591 NPBL have been included in the present study. The suspected grade of each lesion was then assigned according to the Breast Imaging Reporting and Data System (BI-RADS) of the American College of Radiology. All the BI-RADS 4 and 5, and all the BI-RADS 3 lesions, which after 6-month follow-up showed altered morphology, were sampled for cytological and/or histological examinations by FNAC, VACB or biopsy by ABBI system. The diagnostic algorithm used in this study obviated a surgical procedure in 574 women (97.1%), yielding a 73.9% decrease in the cost of diagnosis compared with surgical biopsy, and a 48.1% decrease in cost if all lesions had been histologically tested using ABBI or VACB procedure. Compared to surgical biopsy, VACB and ABBI system are less expensive, and have smaller emotional and aesthetical impact on patients; however they retain the same sensitivity and specificity.

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Authors and Affiliations

  1. Breast Unit, Campus Bio-Medico University, Rome, Italy

    Vittorio Altomare, Rita Carino & Marilena Montesano

  2. Surgical Scienze Department, Policlinico Umberto I, 'La Sapienza' University, Via Prenestina, 919, 00155, Rome, Italy

    Gabriella Guerriero & Laura Giacomelli

  3. Department of Gynecology, Campus Bio-Medico University, Rome, Italy

    Cleonice Battista

  4. Department of Radiology, Campus Bio-Medico University, Rome, Italy

    Donata Vaccaro

  5. Department of Pathology, Campus Bio-Medico University, Rome, Italy

    Carla Rabitti

Authors
  1. Vittorio Altomare
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  2. Gabriella Guerriero
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  3. Laura Giacomelli
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  4. Cleonice Battista
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  5. Rita Carino
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  6. Marilena Montesano
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  7. Donata Vaccaro
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  8. Carla Rabitti
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Corresponding author

Correspondence to Gabriella Guerriero.

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Altomare, V., Guerriero, G., Giacomelli, L. et al. Management of Nonpalpable Breast Lesions in a Modern Functional Breast Unit. Breast Cancer Res Treat 93, 85–89 (2005). https://doi.org/10.1007/s10549-005-3952-1

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  • DOI: https://doi.org/10.1007/s10549-005-3952-1

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