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Altered Resting-State EEG Microstate Parameters and Enhanced Spatial Complexity in Male Adolescent Patients with Mild Spastic Diplegia

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Abstract

The aim of this study was to investigate the resting-state EEG microstate parameters and spatial complexity in male adolescent patients with mild spastic diplegia (MSD). Resting-state EEG data were collected from male adolescent patients with MSD and healthy controls with eyes closed. EEG microstate and omega complexity analysis were performed. Microstate analysis revealed that the occurrence rate of microstate class A and D were significantly higher and the duration of microstate class B was significantly lower in the patients compared to healthy controls, which indicated that the temporal complexity may be higher and certain cognitive functions may be impaired in these patients. Omega complexity analysis showed that the global omega complexity of alpha-2 band was significantly higher in the patients than the controls. Besides, compared to the anterior regional omega complexities, the posterior regional omega complexities were significantly lower in the delta, theta, alpha-1 and alpha-2 bands, but significantly higher in the beta-2 and gamma-1 bands. And the regional omega complexities in the delta, theta and alpha-1 bands were significantly higher in the patients than controls. The present study reveals that in male adolescent patients with MSD, the temporal and spatial complexities of EEG signal are enhanced, which may be closely associated with the altered brain functions in these patients.

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    Authors and Affiliations

    1. Department of Pain Medicine, Peking University People’s Hospital, No. 11 South Street Xizhimen, Xicheng District, Beijing, China

      Fei Gao & Yi Feng

    2. Key Laboratory of Child Development and Learning Science of Ministry of Education, Research Center for Learning Science, Southeast University, Nanjing, Jiangsu, China

      Huibin Jia & Dongchuan Yu

    3. Institute of Behavioral Psychology, Henan University, Kaifeng, Henan, China

      Xiangci Wu

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    1. Fei Gao
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    2. Huibin Jia
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    3. Xiangci Wu
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    4. Dongchuan Yu
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    5. Yi Feng
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    Correspondence to Dongchuan Yu or Yi Feng.

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    F. Gao and H. Jia contributed equally to this work.

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    Gao, F., Jia, H., Wu, X. et al. Altered Resting-State EEG Microstate Parameters and Enhanced Spatial Complexity in Male Adolescent Patients with Mild Spastic Diplegia. Brain Topogr 30, 233–244 (2017). https://doi.org/10.1007/s10548-016-0520-4

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    • DOI: https://doi.org/10.1007/s10548-016-0520-4

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