Skip to main content
SpringerLink
Log in

Transport of living cells with magnetically assembled nanowires

  • Published:
Biomedical Microdevices Aims and scope Submit manuscript

Abstract

We present a technique of transporting and positioning living cells internalized by nickel (Ni) nanowires guided by magnetic field. Nanoscale magnetic nanowires are internalized by the Rat Neuroblastoma (ATCC number CRL-2754) and the cells are transported and positioned by magnetic fields from the magnetic material-coated electrodes. This technique may enable the interfacing between neurons and electronic devices to empower investigations pertaining to non-invasive neuron probing as well as nanofabricated neural pharmacological technologies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  • B. Devika Chithrani, Arezou A. Ghazani, and Warren C. W. Chan, “Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells,” Nano Letters 6, 662–668 (2006).

    Article  Google Scholar 

  • A. Folch and M. Toner, Ann. Rev. Biomed. Eng. 2, 227–256 (2000).

    Article  Google Scholar 

  • S. Hahn, X. Zhong, C. Troeger, R. Burgemeister, K. Glooning, and W. Holzgreve, Cell Mal. Life Sci. 57, 96–105 (2000).

    Article  Google Scholar 

  • A. Hultgren, M. Tanase, E. Felton, K. Bhadriraju, A. Salem, C. Chen, and D. Reich, Biotechnol. Prog. 21, 509–515 (2005).

    Google Scholar 

  • Y. Kim, J. Soh, and D. Choi. (unpublished data, 2006)

  • B. Kim, K. Yun, and E. Yoon, IEEE MEMS 2005 (2005).

  • N. Myung, J. Lim, J. Fleurial, M. Yun, and D. Choi, Nanotechnology 15, 1 (2004).

    Article  Google Scholar 

  • M. Rubin, Science 296, 1329–1330 (2002).

    Article  Google Scholar 

  • B. Yoo, Y. Rheem, N.V. Myung, D.S. Choi, and E.-H. Yang, “Magnetically Assembled Nanowires,” NASA's New Technology Report, NTR # 42952 (2005).

Download references

Acknowledgments

The authors thank Professor W. Klug (UCLA) for discussions on estimating driving force of transporting the cells internalized with Ni nanowires. We gratefully acknowledge support for this work by the Director's Research & Development Fund 2006. We would like to thank Benjamin Chiang and Stacy Chang for technical assistance with cell imaging. AF gratefully acknowledges a NSERC postgraduate scholarship for study abroad.

Author information

Author notes

  1. D. Ho

    Present address: Department of Mechanical & Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA

Authors and Affiliations

  1. Mechanical & Aerospace Engineering Department, University of California at Los Angeles, Los Angeles, CA, 90095, USA

    D. Choi

  2. Biomedical Engineering Department, University of California at Los Angeles, Los Angeles, CA, 90095, USA

    A. Fung, H. Moon, D. Ho & Y. Chen

  3. US Environmental Protection Agency, National Risk Management Research Laboratory, P.O. Box 1198, Ada, OK, 74820, USA

    E. Kan

  4. Chemical & Environmental Engineering Department, University of California at Riverside, Riverside, CA, 92521, USA

    Y. Rheem, B Yoo & N Myung

Authors
  1. D. Choi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Fung
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Moon
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. Ho
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Y. Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. E. Kan
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Y. Rheem
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. B Yoo
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. N Myung
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. Choi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Choi, D., Fung, A., Moon, H. et al. Transport of living cells with magnetically assembled nanowires. Biomed Microdevices 9, 143–148 (2007). https://doi.org/10.1007/s10544-006-9008-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10544-006-9008-4

Keywords

Search

Navigation