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Molecular Mechanisms of Epigenetics

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Abstract

The main epigenetic mechanisms in regulation of gene expression are discussed. The definition of epigenetics and its specific mechanisms including DNA methylation and gene imprinting, modifications of nucleosomal histones associated with silencing or activation of gene transcription, RNA interference, chromosomal silencing, and the role of mobile elements are discussed.

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  1. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, 119991, Moscow, Russia

    N. A. Tchurikov

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__________

Translated from Biokhimiya, Vol. 70, No. 4, 2005, pp. 493–513.

Original Russian Text Copyright © 2005 by Tchurikov.

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Tchurikov, N.A. Molecular Mechanisms of Epigenetics. Biochemistry (Moscow) 70, 406–423 (2005). https://doi.org/10.1007/s10541-005-0131-2

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