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Catalytic mechanism and application of formate dehydrogenase

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Abstract

NAD+-dependent formate dehydrogenase (FDH) is an abundant enzyme that plays an important role in energysupply of methylotrophic microorganisms and in response to stress in plants. FDH belongs to the superfamily of D-specific 2-hydroxy acid dehydrogenases. FDH is widely accepted as a model enzyme to study the mechanism of hydride ion transfer in the active center of dehydrogenases because the reaction catalyzed by the enzyme is devoid of proton transfer steps and implies a substrate with relatively simple structure. FDH is also widely used in enzymatic syntheses of optically active compounds as a versatile biocatalyst for NAD(P)H regeneration consumed in the main reaction. This review covers the late developments in cloning genes of FDH from various sources, studies of its catalytic mechanism and physiological role, and its application for new chiral syntheses.

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REFERENCES

  1. C. Vinals E. Depiereux E. Feytmans (1993) Biochem. Biophys. Res. Commun. 192 182–188 Occurrence Handle8476420 Occurrence Handle1:CAS:528:DyaK3sXksVCitLc%3D Occurrence Handle10.1006/bbrc.1993.1398

    Article  PubMed  CAS  Google Scholar 

  2. R. Wichmann C. Wandrey A. F. Buckmann M. R. Kula (1981) Biotechnol. Bioeng. 23 2789–2802 Occurrence Handle1:CAS:528:DyaL38XjtVOqtA%3D%3D Occurrence Handle10.1002/bit.260231213

    Article  CAS  Google Scholar 

  3. W. Hummel M. R. Kula (1989) Eur. J. Biochem. 184 1–13 Occurrence Handle2673781 Occurrence Handle1:CAS:528:DyaL1MXlvFSmsbs%3D Occurrence Handle10.1111/j.1432-1033.1989.tb14983.x

    Article  PubMed  CAS  Google Scholar 

  4. H. Zhao W. A. Donk Particlevan der (2003) Curr. Opin. Biotechnol. 14 583–589 Occurrence Handle14662386 Occurrence Handle1:CAS:528:DC%2BD3sXps1Oqt74%3D Occurrence Handle10.1016/j.copbio.2003.09.007

    Article  PubMed  CAS  Google Scholar 

  5. A. S. Bommarius M. Schwarm K. Stingl M. Kottenhahn K. Huthmacher K. Drauz (1995) Tetrahedron: Asymmetry 6 2851–2888 Occurrence Handle1:CAS:528:DyaK28XhvFaitQ%3D%3D Occurrence Handle10.1016/0957-4166(95)00377-0

    Article  CAS  Google Scholar 

  6. V. O. Popov V. S. Lamzin (1994) Biochem. J. 301 625–643 Occurrence Handle8053888 Occurrence Handle1:CAS:528:DyaK2cXlt1ygtrw%3D

    PubMed  CAS  Google Scholar 

  7. V. O. Popov V. I. Tishkov (2003) NoChapterTitle V. N. Uversky (Eds) Protein Structures: Kaleidoscope of Structural Properties and Functions Research Signpost Kerala, India 441–473

    Google Scholar 

  8. Rodionov, Yu. V. (1981) Usp. Mikrobiol., No.16, 104–138.

  9. S. V. Khangulov V. N. Gladyshev G. C. Dismukes T. C. Stadtman (1998) Biochemistry 37 3518–3528 Occurrence Handle10.1021/bi972177k Occurrence Handle1:CAS:528:DyaK1cXhtFaqurs%3D Occurrence Handle9521673

    Article  CAS  PubMed  Google Scholar 

  10. Hollenberg, C. P., and Janowicz, Z. (1989) Eur. Patent EP1987000110417, Bulletin 89/03.

  11. V. I. Tishkov A. G. Galkin A. M. Egorov (1991) Dokl. Akad. Nauk SSSR 317 345–348

    Google Scholar 

  12. A. Galkin L. Kulakova V. Tishkov N. Esaki K. Soda (1995) Appl. Microbiol. Biotechnol. 44 479–483 Occurrence Handle8597552 Occurrence Handle1:CAS:528:DyaK28XitVertrc%3D Occurrence Handle10.1007/BF00169947

    Article  PubMed  CAS  Google Scholar 

  13. Mitsunaga, T., Tanaka, Y., Yoshida, T., and Watanabe, K. (2000) Jap. Patent JP245471A2 of 12.09.2000.

  14. T. Shinoda T. Satoh S. Mineki M. Iida H. Taguchi (2002) Biosci. Biotechnol. Biochem. 66 271–276 Occurrence Handle11999398 Occurrence Handle1:CAS:528:DC%2BD38XitVWlsr8%3D Occurrence Handle10.1271/bbb.66.271

    Article  PubMed  CAS  Google Scholar 

  15. H. Nanba Y. Takaoka J. Hasegawa (2003) Biosci. Biotechnol. Biochem. 67 720–728 Occurrence Handle12784610 Occurrence Handle1:CAS:528:DC%2BD3sXjslOmt7Y%3D Occurrence Handle10.1271/bbb.67.720

    Article  PubMed  CAS  Google Scholar 

  16. H. Nanba Y. Takaoka J. Hasegawa (2003) Biosci. Biotechnol. Biochem. 67 2145–2153 Occurrence Handle14586102 Occurrence Handle1:CAS:528:DC%2BD3sXovVyhs7Y%3D Occurrence Handle10.1271/bbb.67.2145

    Article  PubMed  CAS  Google Scholar 

  17. S. J. Allen J. J. Holbrook (1995) Gene 162 99–104 Occurrence Handle7557425 Occurrence Handle1:CAS:528:DyaK2MXotFClu70%3D Occurrence Handle10.1016/0378-1119(95)00347-9

    Article  PubMed  CAS  Google Scholar 

  18. Y. Sakai A. P. Murdanoto T. Konishi A. Iwamatsu N. Kato (1997) J. Bacteriol. 179 4480–4485 Occurrence Handle9226256 Occurrence Handle1:CAS:528:DyaK2sXksFCht78%3D

    PubMed  CAS  Google Scholar 

  19. H. Slusarczyk S. Felber M. R. Kula M. Pohl (2000) Eur. J. Biochem. 267 1280–1289 Occurrence Handle10691964 Occurrence Handle1:CAS:528:DC%2BD3cXhvVagsrw%3D Occurrence Handle10.1046/j.1432-1327.2000.01123.x

    Article  PubMed  CAS  Google Scholar 

  20. N. E. Labrou D. J. Rigden (2001) Biochem. J. 354 455–463 Occurrence Handle11171126 Occurrence Handle1:CAS:528:DC%2BD3MXitFWrtr4%3D Occurrence Handle10.1042/0264-6021:3540455

    Article  PubMed  CAS  Google Scholar 

  21. Goldberg, S. L., Cino, P. M., Patel, R. N., Nanduri, V. B., Johnston, R. M., and Johnston, R. (2004) USA Patent US 2004/0038237 Al of 26.02.2004.

  22. T. Baba F. Takeuchi M. Kuroda H. Yuzawa K. I. Aoki A. Oguchi Y. Nagai N. Iwama K. Asano T. Naimi H. Kuroda L. Cui K. Yamamoto K. Hiramatsu (2002) Lancet 359 1819–1827 Occurrence Handle12044378 Occurrence Handle1:CAS:528:DC%2BD38XktVaku7w%3D Occurrence Handle10.1016/S0140-6736(02)08713-5

    Article  PubMed  CAS  Google Scholar 

  23. J. Parkhill M. Sebaihia A. Preston L. D. Murphy N. Thomson D. E. Harris M. T. G. Holden C. M. Churcher S. D. Bentley K. L. Mungall A. M. Cerdeno-Tarraga L. Temple K. James B. Harris M. A. Quail M. Achtman R. Atkin S. Baker D. Basham N. Bason I. Cherevach T. Chillingworth M. Collins A. Cronin P. Davis J. Doggett T. Feltwell A. Goble N. Hamlin H. Hauser S. Holroyd K. Jagels S. Leather S. Moule H. Norberczak S. O’Niel D. Ormond C. Price E. Rabbinowitsch S. Rutter M. Sanders D. Saunders K. Seeger S. Sharp M. Simmonds J. Skelton R. Squares S. Squares K. Stevens L. Unwin S. Whitehead B. G. Barrell D. J. Maskell (2003) Nat. Genet. 35 32–40 Occurrence Handle12910271 Occurrence Handle10.1038/ng1227

    Article  PubMed  Google Scholar 

  24. S. Omura H. Ikeda J. Ishikawa A. Hanamoto C. Takahashi M. Shinose Y. Takahashi H. Horikawa H. Nakazawa T. Osonoe H. Kikuchi T. Shiba Y. Sakaki M. Hattori (2001) Proc. Natl. Acad. Sci. USA 98 12215–12220 Occurrence Handle11572948 Occurrence Handle1:CAS:528:DC%2BD3MXns1Cjtrk%3D Occurrence Handle10.1073/pnas.211433198

    Article  PubMed  CAS  Google Scholar 

  25. J. R. Torre ParticleDe la L. M. Christianson O. Beja M. T. Suzuki D. M. Karl J. Heidelberg E. F. Long ParticleDe (2003) Proc. Natl. Acad. Sci. USA 100 12830–12835 Occurrence Handle14566056 Occurrence Handle10.1073/pnas.2133554100 Occurrence Handle1:CAS:528:DC%2BD3sXoslKnur8%3D

    Article  PubMed  CAS  Google Scholar 

  26. O. Beja L. Aravind E. V. Koonin M. T. Suzuki A. Hadd L. P. Nguyen S. B. Jovanovich C. M. Gates R. A. Feldman J. L. Spudich E. N. Spudich E. F. Long ParticleDe (2000) Science 289 1902–1906 Occurrence Handle10.1126/science.289.5486.1902 Occurrence Handle1:CAS:528:DC%2BD3cXms1amsrc%3D Occurrence Handle10988064

    Article  CAS  PubMed  Google Scholar 

  27. M. J. Barnett R. F. Fisher T. Jones C. Komp A. P. Abola F. Barloy Hubler L. Bowser D. Capela F. Galibert J. Gouzy M. Gurjal A. Hong L. Huizar R. W. Hyman D. Kahn M. L. Kahn S. Kalman D. H. Keating C. Palm M. C. Peck R. Surzycki D. H. Wells K. C. Yeh R. W. Davis N. A. Federspiel S. R. Long (2001) Proc. Natl. Acad. Sci. USA 98 9883–9888 Occurrence Handle11481432 Occurrence Handle1:CAS:528:DC%2BD3MXmtlCmsbw%3D Occurrence Handle10.1073/pnas.161294798

    Article  PubMed  CAS  Google Scholar 

  28. J. L. Souciet M. Aigle F. Artiguenave G. Blandin M. Bolotin-Fukuhara E. Bon P. Brottier S. Casaregola J. Montigny Particlede B. Dujon P. Durrens A. Lepingle B. Llorente A. Malpertuy C. Neuveglise O. Ozier-Kalogeropoulos S. Potier W. Saurin F. Tekaia C. Toffano-Nioche M. Wesolowski-Louvel P. Wincker J. Weissenbach (2000) FEBS Lett. 487 3–12 Occurrence Handle11152876 Occurrence Handle10.1016/S0014-5793(00)02272-9

    Article  PubMed  Google Scholar 

  29. S. Ostergaard L. Olsson J. Nielsen (2000) Microbiol. Rev. 64 34–50 Occurrence Handle1:CAS:528:DC%2BD3cXitFyhu7c%3D

    CAS  Google Scholar 

  30. K. M. Overkamp P. Kotter H. R. Der Particlevan S. Schoondermark-Stolk M. A. H. Luttik J. P. Dijken Particlevan J. T. Pronk (2002) Yeast 19 509–520 Occurrence Handle11921099 Occurrence Handle1:CAS:528:DC%2BD38Xjt1eis70%3D Occurrence Handle10.1002/yea.856

    Article  PubMed  CAS  Google Scholar 

  31. A. E. Serov (2002) Structure—Function Relationships in Recombinant Formate Dehydrogenases from Baker’s Yeast and Methylotrophic Bacteria Lomonosov Moscow State University Moscow

    Google Scholar 

  32. A. E. Serov A. S. Popova V. I. Tishkov (2002) Doklady RAN 382 401–405

    Google Scholar 

  33. J. A. Saleeba C. S. Cobbett M. J. Hynes (1992) Mol. Gen. Genet. 235 349–358 Occurrence Handle1465107 Occurrence Handle1:CAS:528:DyaK3sXktVahsLo%3D Occurrence Handle10.1007/BF00279380

    Article  PubMed  CAS  Google Scholar 

  34. C. M. Chow U. L. Raj Bhandary (1993) J. Bacteriol. 175 3703–3709 Occurrence Handle8509325 Occurrence Handle1:CAS:528:DyaK3sXms1eksbY%3D

    PubMed  CAS  Google Scholar 

  35. D. C. Davison (1951) Biochem. J. 49 520–526 Occurrence Handle14886318 Occurrence Handle1:CAS:528:DyaG38XlvVKl

    PubMed  CAS  Google Scholar 

  36. T. Kanamori Y. Suzuki (1968) Enzymologia 35 185–197 Occurrence Handle4301624 Occurrence Handle1:CAS:528:DyaF1MXovFCq

    PubMed  CAS  Google Scholar 

  37. D. Peacock D. Boulter (1970) Biochem. J. 120 763–769 Occurrence Handle4322039 Occurrence Handle1:CAS:528:DyaE3MXmtFWitg%3D%3D

    PubMed  CAS  Google Scholar 

  38. T. Ohyama I. Yamazaki (1974) J. Biochem. (Tokyo) 75 1257–1263 Occurrence Handle1:CAS:528:DyaE2cXkvVOjuro%3D

    CAS  Google Scholar 

  39. T. Ohyama I. Yamazaki (1975) J. Biochem. (Tokyo) 77 845–852 Occurrence Handle1:CAS:528:DyaE2MXkt1Ciur8%3D

    CAS  Google Scholar 

  40. C. Colas des Francs-Small F. Ambard-Bretteville A. Darpas M. Sallantin J. C. Huet J. C. Pernollet R. Remy (1992) Plant Physiol. 98 273–278 Occurrence Handle1:CAS:528:DyaK38Xht1Cqsbk%3D

    CAS  Google Scholar 

  41. C. Colas des Francs-Small F. Ambard-Bretteville I. D. Small R. Remy (1993) Plant Physiol. 102 1171–1177 Occurrence Handle8278546 Occurrence Handle1:CAS:528:DyaK2cXltVWjtg%3D%3D Occurrence Handle10.1104/pp.102.4.1171

    Article  PubMed  CAS  Google Scholar 

  42. F. Ambard-Bretteville I. Small O. Grandjean C. Colas des Francs-Small (2003) Biochem. Biophys. Res. Commun. 311 966–971 Occurrence Handle14623276 Occurrence Handle1:CAS:528:DC%2BD3sXovVeisb8%3D Occurrence Handle10.1016/j.bbrc.2003.10.099

    Article  PubMed  CAS  Google Scholar 

  43. L. Jansch V. Kruft U. K. Schmitz H. P. Braun (1996) Plant J. 9 357–368 Occurrence Handle8919912 Occurrence Handle1:STN:280:DyaK2s%2Fnslentw%3D%3D Occurrence Handle10.1046/j.1365-313X.1996.09030357.x

    Article  PubMed  CAS  Google Scholar 

  44. C. Hourton-Cabassa F. Ambard-Bretteville F. Moreau J. D. Virville Particlede R. Remy C. Colas des Francs-Small (1998) Plant Physiol. 116 627–635 Occurrence Handle9490763 Occurrence Handle1:CAS:528:DyaK1cXht1aju7c%3D Occurrence Handle10.1104/pp.116.2.627

    Article  PubMed  CAS  Google Scholar 

  45. K. Suzuki R. Itai K. Suzuki H. Nakanishi N. K. Nishizawa E. Yoshimura S. Mori (1998) Plant Physiol. 116 725–732 Occurrence Handle9489019 Occurrence Handle1:CAS:528:DyaK1cXht1ais78%3D Occurrence Handle10.1104/pp.116.2.725

    Article  PubMed  CAS  Google Scholar 

  46. P. Thompson C. G. Bowsher A. K. Tobin (1998) Plant Physiol. 118 1089–1099 Occurrence Handle9808754 Occurrence Handle1:CAS:528:DyaK1cXnsFektbc%3D Occurrence Handle10.1104/pp.118.3.1089

    Article  PubMed  CAS  Google Scholar 

  47. F. Ambard-Bretteville C. Sorin F. Rebeille C. Hourton-Cabassa C. Colas des Francs-Small (2003) Plant Mol. Biol. 52 1153–1168 Occurrence Handle14682615 Occurrence Handle1:CAS:528:DC%2BD3sXptVCqt7Y%3D Occurrence Handle10.1023/B:PLAN.0000004306.96945.ef

    Article  PubMed  CAS  Google Scholar 

  48. A. D. Hanson D. A. Gage Y. Shachar-Hill (2000) Trends Plant Sci. 5 206–213 Occurrence Handle10785666 Occurrence Handle1:STN:280:DC%2BD3c3kvFalsA%3D%3D Occurrence Handle10.1016/S1360-1385(00)01599-5

    Article  PubMed  CAS  Google Scholar 

  49. J. Kreuzwieser J. P. Schnitzler R. Steinbrecher (1999) Plant Biol. 1 149–159 Occurrence Handle1:CAS:528:DyaK1MXitlajsLY%3D Occurrence Handle10.1111/j.1438-8677.1999.tb00238.x

    Article  CAS  Google Scholar 

  50. R. Li B. Ziola J. King (2000) J. Plant Physiol. 157 161–167 Occurrence Handle1:CAS:528:DC%2BD3cXms1ygt78%3D

    CAS  Google Scholar 

  51. B. J. Olson M. Skavdahl H. Ramberg J. C. Osterman J. Markwell (2000) Plant Sci. 159 205–212 Occurrence Handle11074273 Occurrence Handle1:CAS:528:DC%2BD3cXovFSltrs%3D Occurrence Handle10.1016/S0168-9452(00)00337-X

    Article  PubMed  CAS  Google Scholar 

  52. T. Shiraishi E. Fukusaki A. Kobayashi (2000) J. Biosci. Bioeng. 89 241–246 Occurrence Handle16232736 Occurrence Handle1:CAS:528:DC%2BD3cXjsFent70%3D Occurrence Handle10.1016/S1389-1723(00)88826-X

    Article  PubMed  CAS  Google Scholar 

  53. R. Li P. C. Bonham-Smith J. King (2001) Canad. J. Botany Revue Canadienne de Botanique 79 796–804 Occurrence Handle1:CAS:528:DC%2BD3MXmsV2kt78%3D Occurrence Handle10.1139/cjb-79-7-796

    Article  CAS  Google Scholar 

  54. P. L. Herman H. Ramberg R. D. Baack J. Markwell J. C. Osterman (2002) Plant Sci. 163 1137–1145 Occurrence Handle1:CAS:528:DC%2BD38XosFCmtrs%3D Occurrence Handle10.1016/S0168-9452(02)00326-6

    Article  CAS  Google Scholar 

  55. R. Li M. Moore J. King (2003) Plant Cell Physiol. 44 233–241 Occurrence Handle12668769 Occurrence Handle1:CAS:528:DC%2BD3sXivVWitro%3D Occurrence Handle10.1093/pcp/pcg029

    Article  PubMed  CAS  Google Scholar 

  56. K. Nakai M. Kanehisa (1992) Genomics 14 897–911 Occurrence Handle1:CAS:528:DyaK3sXhs1Clsbw%3D Occurrence Handle1478671 Occurrence Handle10.1016/S0888-7543(05)80111-9

    Article  CAS  PubMed  Google Scholar 

  57. O. Emannuelsson H. Nielsen G. Heijne Particlevon (1999) Protein Sci. 8 978–984 Occurrence Handle10.1110/ps.8.5.978

    Article  Google Scholar 

  58. R. D. Baack J. Markwell P. L. Herman J. C. Osterman (2003) J. Plant Physiol. 160 445–450 Occurrence Handle12806771 Occurrence Handle1:CAS:528:DC%2BD3sXkvFSmur4%3D Occurrence Handle10.1078/0176-1617-00995

    Article  PubMed  CAS  Google Scholar 

  59. P. A. Weerasinghe M. L. M. C. Weerasekera L. H. J. Holm Particlevan (1999) Biologia Plantarum 42 541–547 Occurrence Handle1:CAS:528:DC%2BD3cXhtVWhsbo%3D Occurrence Handle10.1023/A:1002610914209

    Article  CAS  Google Scholar 

  60. N. V. Bykova H. Egsgaard I. M. Moller (2003) FEBS Lett. 540 141–146 Occurrence Handle12681497 Occurrence Handle1:CAS:528:DC%2BD3sXislCiurk%3D Occurrence Handle10.1016/S0014-5793(03)00250-3

    Article  PubMed  CAS  Google Scholar 

  61. N. V. Bykova A. Stensballe H. Egsgaard O. N. Jensen I. M. Moller (2003) J. Biol. Chem. 278 26021–26030 Occurrence Handle12714601 Occurrence Handle1:CAS:528:DC%2BD3sXlt1CltrY%3D Occurrence Handle10.1074/jbc.M300245200

    Article  PubMed  CAS  Google Scholar 

  62. V. V. Fedorchuk A. G. Galkin I. E. Yasnyi L. B. Kulakova A. M. Rojkova A. A. Filippova V. I. Tishkov (2002) Biochemistry (Moscow) 67 1145–1151 Occurrence Handle1:CAS:528:DC%2BD38XosVClsbk%3D Occurrence Handle10.1023/A:1020915324159

    Article  CAS  Google Scholar 

  63. N. Gul-Karaguler R. B. Sessions A. R. Clarke J. Holbrook (2001) Biotechnol. Lett. 23 283–287 Occurrence Handle1:CAS:528:DC%2BD3MXhs1Sns78%3D Occurrence Handle10.1023/A:1005610414179

    Article  CAS  Google Scholar 

  64. A. E. Serov A. S. Popova V. V. Fedorchuk V. I. Tishkov (2002) Biochem. J. 367 841–847 Occurrence Handle12144528 Occurrence Handle1:CAS:528:DC%2BD38XotFWksrk%3D Occurrence Handle10.1042/BJ20020379

    Article  PubMed  CAS  Google Scholar 

  65. V. S. Lamzin Z. Dauter V. O. Popov E. H. Harutyunyan K. S. Wilson (1994) J. Mol. Biol. 236 759–785 Occurrence Handle8114093 Occurrence Handle1:CAS:528:DyaK2cXis1Cmsrk%3D Occurrence Handle10.1006/jmbi.1994.1188

    Article  PubMed  CAS  Google Scholar 

  66. C. E. Shannon (1997) MD Comput. 14 306–317 Occurrence Handle9230594 Occurrence Handle1:STN:280:DyaK2sznsVWntg%3D%3D

    PubMed  CAS  Google Scholar 

  67. A. G. Wilson (1970) Entropy in Urban and Regional Modelling Pion Limited London

    Google Scholar 

  68. C. Sander R. Schneider (1991) Proteins 9 56–68 Occurrence Handle1:CAS:528:DyaK3MXhtVSlsrw%3D Occurrence Handle2017436 Occurrence Handle10.1002/prot.340090107

    Article  CAS  PubMed  Google Scholar 

  69. V. I. Tishkov A. D. Matorin A. M. Rojkova V. V. Fedorchuk P. A. Savitsky L. A. Dementieva V. S. Lamzin A. V. Mezentzev V. O. Popov (1996) FEBS Lett. 390 104–108 Occurrence Handle8706817 Occurrence Handle1:CAS:528:DyaK28Xkt12qsLo%3D Occurrence Handle10.1016/0014-5793(96)00641-2

    Article  PubMed  CAS  Google Scholar 

  70. M. Iida K. Kitamura-Kimura H. Maeda S. Mineki (1992) Biosci. Biotechnol. Biochem. 56 1966–1970 Occurrence Handle1:CAS:528:DyaK3sXhs1ersrc%3D Occurrence Handle10.1271/bbb.56.1966

    Article  CAS  Google Scholar 

  71. Tishkov, V. I., Galkin, A. G., Gladyshev, V. N., Karzanov, V. V., and Egorov, A. M. (1992) Biotekhnologiya, No. 5, 52–59.

  72. A. V. Mezentsev T. B. Ustinnikova T. V. Tikhonova V. O. Popov (1996) Prikl. Biokhim. Mikrobiol. 32 589–595 Occurrence Handle1:CAS:528:DyaK2sXlt1Wnsw%3D%3D

    CAS  Google Scholar 

  73. Slusarczyk, H., Felber, S., Kula, M. R., and Pohl, M. (2003) Eur. Patent EP1295937 A2N of 26.03.2003.

  74. V. O. Popov I. A. Shumilin T. B. Ustinnikova V. S. Lamzin T. A. Egorov (1990) Bioorg. Khim. 16 324–335 Occurrence Handle2357236 Occurrence Handle1:CAS:528:DyaK3cXkslelu70%3D

    PubMed  CAS  Google Scholar 

  75. V. I. Tishkov (2002) Bull. Moscow Univ., Ser. 2, Chemistry 43 380–387

    Google Scholar 

  76. J. S. Blanchard W. W. Cleland (1980) Biochemistry 19 3543–3550 Occurrence Handle6996706 Occurrence Handle1:CAS:528:DyaL3cXkvFSqu7w%3D Occurrence Handle10.1021/bi00556a020

    Article  PubMed  CAS  Google Scholar 

  77. J. D. Hermes S. W. Morrical M. H. O’Leary W. W. Cleland (1984) Biochemistry 23 5479–5488 Occurrence Handle6391544 Occurrence Handle1:CAS:528:DyaL2cXmtVKlt74%3D Occurrence Handle10.1021/bi00318a016

    Article  PubMed  CAS  Google Scholar 

  78. V. I. Tishkov A. G. Galkin A. M. Egorov (1989) Biokhimiya 54 299–305 Occurrence Handle1:CAS:528:DyaL1MXhs1yqsrc%3D

    CAS  Google Scholar 

  79. V. O. Popov A. M. Egorov I. V. Berezin (1978) Dokl. Akad. Nauk SSSR 240 217–220 Occurrence Handle1:CAS:528:DyaE1cXksFGms74%3D

    CAS  Google Scholar 

  80. V. I. Tishkov A. G. Galkin A. M. Egorov (1989) Biochimie 71 551–557 Occurrence Handle2503060 Occurrence Handle1:CAS:528:DyaL1MXktlGlu7o%3D Occurrence Handle10.1016/0300-9084(89)90186-7

    Article  PubMed  CAS  Google Scholar 

  81. J. A. Bocanegra N. S. Scrutton R. N. Perham (1993) Biochemistry 32 2737–2740 Occurrence Handle8457541 Occurrence Handle1:CAS:528:DyaK3sXhvVKrs7c%3D Occurrence Handle10.1021/bi00062a001

    Article  PubMed  CAS  Google Scholar 

  82. Z. Chen W. R. Lee S. H. Chang (1991) Eur. J. Biochem. 202 263–267 Occurrence Handle1761031 Occurrence Handle1:CAS:528:DyaK38Xjs12gtw%3D%3D Occurrence Handle10.1111/j.1432-1033.1991.tb16371.x

    Article  PubMed  CAS  Google Scholar 

  83. Z. Chen I. Tsigelny W. R. Lee M. E. Baker S. H. Chang (1994) FEBS Lett. 356 81–85 Occurrence Handle7988726 Occurrence Handle1:CAS:528:DyaK2MXjtVSms7Y%3D Occurrence Handle10.1016/0014-5793(94)01234-2

    Article  PubMed  CAS  Google Scholar 

  84. R. Chen A. Greer A. M. Dean (1996) Proc. Natl. Acad. Sci. USA 93 12171–12176 Occurrence Handle8901552 Occurrence Handle1:CAS:528:DyaK28Xms1Gjs78%3D Occurrence Handle10.1073/pnas.93.22.12171

    Article  PubMed  CAS  Google Scholar 

  85. V. I. Tishkov A. G. Galkin A. M. Egorov (1993) Proc. Int. Conf. “Enzyme Engineering XII” Deu Ville France 54

    Google Scholar 

  86. H. Shutte J. Flossdorf H. Sahm M. R. Kula (1976) Eur. J. Biochem. 62 151–160 Occurrence Handle10.1111/j.1432-1033.1976.tb10108.x

    Article  Google Scholar 

  87. V. O. Popov Y. V. Rodionov A. M. Egorov I. V. Berezin (1978) Bioorg. Khim. 4 117–129 Occurrence Handle1:CAS:528:DyaE1cXhtFKqtL4%3D

    CAS  Google Scholar 

  88. R. D. La Reau V. E. Anderson (1989) J. Biol. Chem. 264 15338–15343 Occurrence Handle1:CAS:528:DyaK3cXjsVWh

    CAS  Google Scholar 

  89. E. G. Weinhold A. Glasfeld A. D. Ellington A. Benner (1991) Proc. Natl. Acad. Sci. USA 88 8420–8424 Occurrence Handle1924300 Occurrence Handle1:CAS:528:DyaK38Xjs1ykug%3D%3D Occurrence Handle10.1073/pnas.88.19.8420

    Article  PubMed  CAS  Google Scholar 

  90. Z. Shaked G. M. Whitesides (1980) J. Am. Chem. Soc. 102 7104–7105 Occurrence Handle1:CAS:528:DyaL3cXmtlCnsLs%3D Occurrence Handle10.1021/ja00543a038

    Article  CAS  Google Scholar 

  91. A. V. Mesentsev V. S. Lamzin V. I. Tishkov T. B. Ustinnikova V. O. Popov (1997) Biochem. J. 321 475–480 Occurrence Handle9020883 Occurrence Handle1:CAS:528:DyaK2sXotFOgsw%3D%3D

    PubMed  CAS  Google Scholar 

  92. W. Neuhauser M. Steininger D. Haltrich K. D. Kulbe B. Nidetzky (1998) Biotechnol. Bioeng. 60 277–282 Occurrence Handle10099429 Occurrence Handle1:CAS:528:DyaK1cXmsVamtb8%3D Occurrence Handle10.1002/(SICI)1097-0290(19981105)60:3<277::AID-BIT2>3.0.CO;2-E

    Article  PubMed  CAS  Google Scholar 

  93. Berezin, I. V., Tishkov, V. I., Karzanov, V. V., Avilova, T. V., Egorov, A. M., Petkyavichene, R. I., Vaitkyavichus, R. K., and Glemzha, A. A. (1989) USSR Patent, No. 1479513, Byul. Izobret. (1989) No. 18.

  94. D. Weusterbotz C. Wandrey (1995) Proc. Biochem. 30 563–571 Occurrence Handle1:CAS:528:DyaK2MXmsFyqtLg%3D Occurrence Handle10.1016/0032-9592(94)00036-H

    Article  CAS  Google Scholar 

  95. N. E. Labrou D. J. Rigden Y. D. Clonis (2000) Eur. J. Biochem. 267 6657–6664 Occurrence Handle11054119 Occurrence Handle1:CAS:528:DC%2BD3cXotF2qt7w%3D Occurrence Handle10.1046/j.1432-1327.2000.01761.x

    Article  PubMed  CAS  Google Scholar 

  96. K. Seelbach B. Riebel W. Hummel M. R. Kula V. I. Tishkov A. M. Egorov C. Wandrey U. Kragl (1996) Tetrahedron Lett. 37 1377–1380 Occurrence Handle1:CAS:528:DyaK28XhsFWrtb4%3D Occurrence Handle10.1016/0040-4039(96)00010-X

    Article  CAS  Google Scholar 

  97. D. Weuster-Botz H. Paschold B. Striegel H. Gieren M. R. Kula C. Wandrey (1994) Chem. Eng. Technol. 17 131–137 Occurrence Handle1:CAS:528:DyaK2MXivVSkt7o%3D Occurrence Handle10.1002/ceat.270170211

    Article  CAS  Google Scholar 

  98. Yu. V. Rodionov T. V. Avilova V. O. Popov (1977) Biokhimiya 42 2020–2026 Occurrence Handle1:CAS:528:DyaE1cXjtlOqtQ%3D%3D

    CAS  Google Scholar 

  99. V. I. Tishkov A. G. Galkin G. N. Marchenko O. A. Egorova D. V. Sheluho L. B. Kulakova L. A. Dementieva A. M. Egorov (1993) Biochem. Biophys. Res. Commun. 192 976–981 Occurrence Handle8484798 Occurrence Handle1:CAS:528:DyaK3sXisFSltLs%3D Occurrence Handle10.1006/bbrc.1993.1511

    Article  PubMed  CAS  Google Scholar 

  100. E. R. Odintseva A. S. Popova A. M. Rojkova V. I. Tishkov (2002) Bull. Moscow Univ., Ser. 2, Chemistry 43 356–359 Occurrence Handle1:CAS:528:DC%2BD3sXitFSmtbc%3D

    CAS  Google Scholar 

  101. Mitsuhashi, K., Yamamoto, H., and Kimoto, N. (2001) Eur. Patent EP1211316 A of 27.11.2001.

  102. A. M. Rojkova A. G. Galkin L. B. Kulakova A. E. Serov P. A. Savitsky V. V. Fedorchuk V. I. Tishkov (1999) FEBS Lett. 445 183–188 Occurrence Handle10069397 Occurrence Handle1:CAS:528:DyaK1MXht1Ogs7g%3D Occurrence Handle10.1016/S0014-5793(99)00127-1

    Article  PubMed  CAS  Google Scholar 

  103. A. E. Serov V. I. Tishkov (2002) Bull. Moscow Univ., Ser. 2, Chemistry 43 345–349 Occurrence Handle1:CAS:528:DC%2BD3sXitVOqsrk%3D

    CAS  Google Scholar 

  104. Serov, A. E., Odintseva, E. R., Uporov, I. V., and Tishkov, V. I. (2005) Biochemistry (Moscow), in press.

  105. V. I. Tishkov A. G. Galkin V. V. Fedorchuk P. A. Savitsky A. M. Rojkova H. Gieren M. R. Kula (1999) Biotechnol. Bioeng. 64 187–193 Occurrence Handle10397854 Occurrence Handle1:CAS:528:DyaK1MXktFWqt70%3D Occurrence Handle10.1002/(SICI)1097-0290(19990720)64:2<187::AID-BIT7>3.0.CO;2-0

    Article  PubMed  CAS  Google Scholar 

  106. U. Reichert E. Knieps H. Slusarczyk M. R. Kula J. Thommes (2001) J. Biochem. Biophys. Meth. 49 533–552 Occurrence Handle11694300 Occurrence Handle1:CAS:528:DC%2BD3MXnvFCmuro%3D Occurrence Handle10.1016/S0165-022X(01)00218-4

    Article  PubMed  CAS  Google Scholar 

  107. M. Leonida (2001) Curr. Med. Chem. 8 345–369 Occurrence Handle11172694 Occurrence Handle1:CAS:528:DC%2BD3MXhs1Kkur0%3D

    PubMed  CAS  Google Scholar 

  108. U. T. Bornscheuer M. Pohl (2001) Curr. Opin. Chem. Biol. 5 137–143 Occurrence Handle11282339 Occurrence Handle1:CAS:528:DC%2BD3MXjt1Wks7o%3D Occurrence Handle10.1016/S1367-5931(00)00182-4

    Article  PubMed  CAS  Google Scholar 

  109. W. Hummel (1999) Trends Biotechnol. 17 487–492 Occurrence Handle10557162 Occurrence Handle1:CAS:528:DyaK1MXntlegtLc%3D Occurrence Handle10.1016/S0167-7799(98)01207-4

    Article  PubMed  CAS  Google Scholar 

  110. U. Kragl W. Kruse W. Hummel C. Wandrey (1996) Biotechnol. Bioeng. 52 309–319 Occurrence Handle1:CAS:528:DyaK28XmtFCmt70%3D Occurrence Handle10.1002/(SICI)1097-0290(19961020)52:2<309::AID-BIT11>3.0.CO;2-E Occurrence Handle18629898

    Article  CAS  PubMed  Google Scholar 

  111. A. Liese M. V. Filho (1999) Curr. Opin. Biotechnol. 10 595–603 Occurrence Handle10600695 Occurrence Handle1:CAS:528:DyaK1MXotFSls78%3D Occurrence Handle10.1016/S0958-1669(99)00040-3

    Article  PubMed  CAS  Google Scholar 

  112. R. N. Patel (2000) Adv. Appl. Microbiol. 47 33–78 Occurrence Handle10.1016/S0065-2164(00)47001-2 Occurrence Handle12876794 Occurrence Handle1:CAS:528:DC%2BD3cXot1WksL0%3D

    Article  PubMed  CAS  Google Scholar 

  113. G. Carrea G. Ottolina (2002) Biocatal. Biotransf. 18 119–132 Occurrence Handle10.3109/10242420009015241

    Article  Google Scholar 

  114. U. Kragl D. VasicRacki C. Wandrey (1996) Bioproc. Eng. 14 291–297 Occurrence Handle1:CAS:528:DyaK28Xjt1yju7c%3D

    CAS  Google Scholar 

  115. K. Seelbach U. Kragl (1997) Enzyme Microb. Technol. 20 389–392 Occurrence Handle1:CAS:528:DyaK2sXitFKkuro%3D Occurrence Handle10.1016/S0141-0229(96)00166-4

    Article  CAS  Google Scholar 

  116. S. Rissom U. Schwarz-Linek M. Vogel V. I. Tishkov U. Kragl (1997) Tetrahedron:Asymmetry 8 2523–2526 Occurrence Handle1:CAS:528:DyaK2sXmtVKiu7k%3D Occurrence Handle10.1016/S0957-4166(97)00311-X

    Article  CAS  Google Scholar 

  117. A. Liese T. Zelinski M. R. Kula H. Kierkels M. Karutz U. Kragl C. Wandrey (1998) J. Mol. Catal. B Enzymatic 4 91–99 Occurrence Handle1:CAS:528:DyaK2sXnsF2hs7o%3D Occurrence Handle10.1016/S1381-1177(97)00025-8

    Article  CAS  Google Scholar 

  118. B. Orlich H. Berger M. Lade R. Schomacker (2000) Biotechnol. Bioeng. 70 638–646 Occurrence Handle11064332 Occurrence Handle1:CAS:528:DC%2BD3cXoslajtLw%3D Occurrence Handle10.1002/1097-0290(20001220)70:6<638::AID-BIT5>3.0.CO;2-#

    Article  PubMed  CAS  Google Scholar 

  119. T. Zelinski A. Liese C. Wandrey M. R. Kula (1999) Tetrahedron:Asymmetry 10 1681–1687 Occurrence Handle1:CAS:528:DyaK1MXksF2lsrc%3D Occurrence Handle10.1016/S0957-4166(99)00137-8

    Article  CAS  Google Scholar 

  120. A. Galkin L. Kulakova T. Yoshimura K. Soda N. Esaki (1997) Appl. Environ. Microbiol. 63 4651–4656 Occurrence Handle9406383 Occurrence Handle1:CAS:528:DyaK2sXnvV2rsb0%3D

    PubMed  CAS  Google Scholar 

  121. K. Takeshita Y. Ishida G. Takada K. Izumori (2000) J. Biosci. Bioeng. 90 545–548 Occurrence Handle16232907 Occurrence Handle1:CAS:528:DC%2BD3cXos1Sqsrw%3D

    PubMed  CAS  Google Scholar 

  122. A. Galkin L. Kulakova H. Yamamoto K. Tanizawa Y. Tanaka N. Esaki K. Soda (1997) J. Ferment. Bioeng. 83 299–300 Occurrence Handle1:CAS:528:DyaK2sXislKjsrk%3D Occurrence Handle10.1016/S0922-338X(97)80997-X

    Article  CAS  Google Scholar 

  123. U. Schwarz-Linek A. Krodel F. A. Ludwig A. Schulze S. Rissom U. Kragl V. I. Tishkov M. Vogel (2001) Synthesis Stuttgart 33 947–951 Occurrence Handle10.1055/s-2001-13394

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Chemical Enzymology, Faculty of Chemistry, Lomonosov Moscow State University, 119992, Moscow, Russia

    V. I. Tishkov

  2. Bach Institute of Biochemistry, Russian Academy of Sciences, Leninsky pr. 33, 117234, Moscow, Russia

    V. O. Popov

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  1. V. I. Tishkov
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Correspondence to V. I. Tishkov.

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Translated from Biokhimiya, Vol. 69, No. 11, 2004, pp. 1537–1554.

Original Russian Text Copyright © 2004 by Tishkov, Popov.

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Tishkov, V.I., Popov, V.O. Catalytic mechanism and application of formate dehydrogenase. Biochemistry (Moscow) 69, 1252–1267 (2004). https://doi.org/10.1007/s10541-005-0071-x

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