Skip to main content
Log in

Statistical theories of functions and the problem of epidemic disease

  • Published:
Biology & Philosophy Aims and scope Submit manuscript

Abstract

Several decades ago, Christopher Boorse formulated an influential statistical theory of normative biological functions but it has often been claimed that his theory suffers from insuperable problems such as an inability to handle cases of epidemic and universal diseases. This paper develops a new statistical theory of normative functions that is capable of dealing with the notorious problem of epidemic and universal diseases. The theory is also more detailed than its predecessors and offers other important advantages over them. It is argued here that statistical theories of biological functions should not be so quickly dismissed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Notes

  1. Wakefield (1992) argues that the concept of mental disorder in psychiatry involves a harm component along these lines. The same appears to be the case for disease in medicine.

  2. For ease of exposition, I will just say ‘fitness’ from now on to refer to inclusive fitness.

  3. I will shortly define the normal functional range of a trait as consisting of ±2 standard deviations from the mean of its effects in a reference class. Thirty percent is analogous to the very bottom of the normal functional range in a uniform statistical distribution.

  4. It is also possible that the circumstances for performing a function may not arise within certain generations for a species. In that case, their traits would still have normative functions according to SFT so long as it would have been typical for them to perform the function if those circumstances would have arisen. I am thankful to Karen Neander for prompting me to clarify this point.

  5. Standard deviation in statistics is defined as the square root of the variance of a distribution. It shows how much variation there is from the mean value in the distribution.

  6. Source: US census: http://www2.census.gov/census_2000/datasets/demographic_profile/0_United_States/2kh00.pdf.

  7. Source: de Lau and Breteler (2006).

  8. I assume here that the relationship between quantity of snpc dopaminergic neurons and motor function is linear. This may not be entirely accurate.

  9. This paper draws on material from my doctoral dissertation (Kraemer 2012). I am thankful to Karen Neander and Fred Dretske for useful comments and discussion. I am also thankful to Robert Brandon and Alex Rosenberg for raising interesting challenges to the position that I defend here. Finally, I would like to thank the editor of this journal and an anonymous referee for some very helpful suggestions.

References

  • Baublys K (1975) Comments on some recent analyses of functional statements in biology. Philos Sci 42(4):469–486

    Article  Google Scholar 

  • Boorse C (1976) Wright on functions. Philos Rev 85(1):70–86

    Article  Google Scholar 

  • Boorse C (1977) Health as a theoretical concept. Philos Sci 44(4):542–573

    Article  Google Scholar 

  • Boorse C (2002) A rebuttal on functions. In: Ariew A, Cummins R, Perlman M (eds) Functions: new essays in the philosophy of psychology and biology. Oxford University Press, New York

    Google Scholar 

  • Brandon R (1978) Adaptation and evolutionary theory. Stud Hist Philos Sci 9:181–206

    Article  Google Scholar 

  • Buller D (1998) Etiological theories of function: a geographical survey. Biol Philos 13:505–527

    Article  Google Scholar 

  • Cummins R (1975) Functional analysis. J Philos 72(20):741–765

    Article  Google Scholar 

  • Damier P, Hirsch EC, Agid Y, Graybiel AM (1999) The substantia nigra of the human brain II. Patterns of loss of dopamine-containing neurons in Parkinson’s disease. Brain 122:1437–1448

    Article  Google Scholar 

  • de Lau L, Breteler M (2006) Epidemiology of Parkinson’s disease. Lancet Neurol 5:525–535

    Article  Google Scholar 

  • Fearnley J, Lees A (1991) Ageing and Parkinson’s disease: substantia nigra regional selectivity. Brain 114:2283–2301

    Article  Google Scholar 

  • Garson J, Piccinini G (forthcoming) Functions must be performed at appropriate rates in appropriate situations. Brit J Philos Sci

  • He M, Zeng J, Liu Y, Xu J, Pokharel G, Ellwein L (2004) Refractive error and visual impairment in urban children in Southern China. Invest Ophthalmol Vis Sci 45(3):793–799

    Article  Google Scholar 

  • Kingma E (2010) Paracetamol, poison, and polio: why Boorse’s account of function fails to distinguish health and disease. Brit J Philos Sci 61:241–264

    Article  Google Scholar 

  • Kraemer D (2012) Making sense of normative functions and information in neurobiological systems. PhD Dissertation, Duke university, Durham, NC

  • Lang A, Lozano A (1998) Parkinson’s disease. N Engl J Med 339(15):1044–1053

    Article  Google Scholar 

  • Logan N, Davies L, Mallen E, Gilmartin B (2005) Ametropia and ocular biometry in a UK university student population. Optom Vis Sci 82(4):261–266

    Article  Google Scholar 

  • Millikan R (1993) White queen psychology and other essays for Alice. MIT Press, Cambridge

    Google Scholar 

  • Mills S, Beatty J (1979) The propensity interpretation of fitness. Philos Sci 46(2):263–286

    Article  Google Scholar 

  • Neander K (1983) Abnormal psychobiology. PhD dissertation. La Trobe University, Victoria, Australia

  • Neander K (1991) Functions as selected effects: the conceptual analyst’s defense. Philos Sci 58(2):168–184

    Article  Google Scholar 

  • Neander K (2002) Why history matters: four theories of functions. In: Weingarten M, Schlosser G (eds) Warum Geschichte Zahlt: Vier Theorien von Funktionen. Formen der Erklaerung in der Biologie, Verlag fuer Wissenchaft und Bildung

  • Roe K, Murphy D (2011) Function, dysfunction and adaptation? In: Adriaens P, De Block A (eds) Maladapting minds: philosophy, psychiatry, and evolutionary theory. Oxford University Press, USA, pp 216–237

    Google Scholar 

  • Schwartz P (2007) Defining dysfunction: natural selection, design and drawing a line. Philos Sci 74:364–385

    Article  Google Scholar 

  • Tompkins M, Basgall E, Zamrini E, Hill W (1997) Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol 150(1):119–131

    Google Scholar 

  • Wakefield J (1992) The concept of mental disorder: on the boundary between biological facts and social values. Am Psychol 47(3):373–388

    Article  Google Scholar 

  • Walsh D, Ariew A (1996) A taxonomy of functions. Can J Philos 26(4):493–514

    Google Scholar 

  • Wimsatt W (1972) Teleology and the logical structure of function statements. Stud Hist Philos Sci 3(1):1–80

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel M. Kraemer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kraemer, D.M. Statistical theories of functions and the problem of epidemic disease. Biol Philos 28, 423–438 (2013). https://doi.org/10.1007/s10539-013-9365-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10539-013-9365-3

Keywords

Navigation