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What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs

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Abstract

Research-intensive small and medium-sized enterprises (SMEs) play a crucial role in the advancement of the biotechnology industry. This paper explored the impacts of internal and contextual variables on innovative activity in Korea and compared the results of this analysis with previous studies of other countries. Our analysis of 149 Korean biotech SMEs showed that the ratio of R&D expenditure to sales, the ratio of R&D employees to total employees, CEO characteristics, governmental support and international networking are positively correlated with a firm’s innovation performance. The results may help decision makers to better foster SMEs in the Korean biotechnology industry.

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References

  • Arvanitis S (1997) The impact of firm size on innovative activity—an empirical analysis based on Swiss firm data. Small Bus Econ 9:473–490

    Article  Google Scholar 

  • Austin DH (1993) An event-study approach to measuring innovative output: the case of biotechnology. Am Econ Rev 86(2):253–258

    Google Scholar 

  • Becheikh N, Landry R, Amara N (2006) Lessons from innovation empirical studies in the manufacturing sector: a systematic review of the literature from 1993–2003. Technovation 26:644–664

    Article  Google Scholar 

  • Beugelsdijk S, Cornet M (2002) ‘A far friend is worth more than a good neighbor’: proximity and innovation in a small country. J Manage Governance 6(2):169–188

    Article  Google Scholar 

  • Deeds DL, Hill CWL (1996) Strategic alliances and the rate of new product development: an empirical study of entrepreneurial biotechnology firms. J Bus Venturing 11:41–55

    Google Scholar 

  • George G, Zahra SA, Wood DR (2002) The effects of business-university alliances on innovative output and financial performance: a study of publicly traded biotechnology companies. J Bus Venturing 17:577–609

    Article  Google Scholar 

  • Giesecke S (2000) The contrasting roles of government in the development of biotechnology industry in the US and Germany. Technovation 29:205–223

    Google Scholar 

  • Hadjimanolis A (2000) An investigation of innovation antecedents in small firms in the context of a small developing country. R&D Manage 30:235–245

    Article  Google Scholar 

  • Hagedoorn J (1993) Understanding the rationale of strategic technology partnering: interorganizational modes of cooperation and sectoral differences. Strateg Manage J 14:371–385

    Article  Google Scholar 

  • Hall LA, Bagchi-Sen S (2002) A study of R&D, innovation, and business performance in the Canadian biotechnology industry. Technovation 22:231–244

    Article  Google Scholar 

  • Hall LA, Bagchi-Sen S (2007) An analysis of firm-level innovation strategies in the US biotechnology industry. Technovation 27:4–14

    Article  Google Scholar 

  • Hoffman K, Parejo M, Bessant J, Perren L (1998) Small firms, R&D, technology and innovation in the UK: a literature review. Technovation 18(1):39–55

    Article  Google Scholar 

  • Huergo E (2006) The role of technological management as a source of innovation: evidence from Spanish manufacturing firms. Res Policy 35:1377–1388

    Article  Google Scholar 

  • Japan Bioindustry Association (2006) Japan bio-venture statistical survey results. http://www.jba.or.jp/english/jbl/document/23_1_2.html. Accessed March 2008

  • Kenny M (1986) Biotechnology: the university-industrial complex. Yale University Press, Yale

    Google Scholar 

  • Korea Bio Venture Association (KOBIOVEN) http://www.kobioven.or.kr/. Accessed March 2008

  • Liebeskin JP, Oliver AL, Zucker L, Brewer M (1996) Social networks, learning and flexibility: sourcing scientific knowledge in new biotechnology firms. Organ Sci 7(4):428–443

    Article  Google Scholar 

  • Mangematin V, Lemarié S, Boissin J-P, Catherine D, Corolleur F, Coronini R, Trommetter M (2003) Development of SMEs and heterogeneity of trajectories: the case of biotechnology in France. Res Policy 32:621–638

    Article  Google Scholar 

  • Marsh D, Oxley L (2005) Modelling innovative activity in the New Zealand biotechnology sector. Math Comput Simul 69:103–112

    Article  Google Scholar 

  • Park J (2007) Korea Bio-venture 2007. Korea Bio Venture Association (KOBIOVEN)

  • Powell WW, Koput KW, Smith-Doerr L (1996) Interorganizational collaboration and the locus of innovation: networks of learning in biotechnology. ADM Sci Q 41:116–145

    Article  Google Scholar 

  • Romijn H, Albaladejo M (2002) Determinants of innovation capability in small electronics and software firms in southeast England. Res Policy 31:1053–1067

    Article  Google Scholar 

  • Shan W, Walker G, Kogut B (1994) Interfirm cooperation and startup innovation in the biotechnology industry. Strateg Manage J 15:387–394

    Article  Google Scholar 

  • Souitaris V (2002) Technological trajectories as moderators of firm-level determinants of innovation. Res Policy 31:877–898

    Article  Google Scholar 

Download references

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Correspondence to Yoon-Sik Lee.

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Kang, KN., Lee, YS. What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs. Biotechnol Lett 30, 1699–1704 (2008). https://doi.org/10.1007/s10529-008-9745-y

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  • DOI: https://doi.org/10.1007/s10529-008-9745-y

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