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Oxidation of butane to butanol coupled to electrochemical redox reaction of NAD+/NADH

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Abstract

A crude cell extract from a butane-utilizing bacterium, Alcaligenes sp., catalyzed the oxidation of butane to butanol coupled to NADH. A graphite electrode modified with Neutral Red (NR-electrode) catalyzed the reduction of NAD+ to NADH. About 4.9 mM butanol was produced from 50% n-butane/O2 mixture through the combined reactions of the crude enzyme and the NR-electrode in 250 ml reactor for 3 h.

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Correspondence to Doo Hyun Park.

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Kang, H.S., Na, B.K. & Park, D.H. Oxidation of butane to butanol coupled to electrochemical redox reaction of NAD+/NADH. Biotechnol Lett 29, 1277–1280 (2007). https://doi.org/10.1007/s10529-007-9385-7

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  • DOI: https://doi.org/10.1007/s10529-007-9385-7

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