Abstract
Phenyllactic acid (PLA) is a novel antimicrobial compound derived from phenylalanine (Phe). Lactobacillus sp. SK007, having high PLA-producing ability, was isolated from Chinese traditional pickles. When 6.1 mM phenylpyruvic acid (PPA) was used to replace Phe as substrate at the same concentration, PLA production increased 14-fold and the fermentation time decreased from 72 h to 24 h with growing cells. With resting cells, however, 6.8 mM PLA could be obtained as optimal yield using the following conditions: 12 mM PPA, 55 mM glucose, pH 7.5, 35°C and 4 h.
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This research was sponsored by the National Natural Science Foundation of China (No. 20376029).
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Li, X., Jiang, B. & Pan, B. Biotransformation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp.. Biotechnol Lett 29, 593–597 (2007). https://doi.org/10.1007/s10529-006-9275-4
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DOI: https://doi.org/10.1007/s10529-006-9275-4