Abstract
Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing extended life expectancy, hence considering them as biomarkers of age-related diseases onset and development. The present study shows no significant differences between allelic variations of ABO blood groups among a group of centenarians from Western Sicily.
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Acknowledgments
This work was supported by grants from the Italian Ministry of Education, University and Research to CC. LC was PhD student at Pathobiology Course of Palermo University (directed by CC) and this paper was in partial fulfillment of the requirement for her PhD.
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Vasto, S., Caruso, C., Castiglia, L. et al. Blood group does not appear to affect longevity a pilot study in centenarians from Western Sicily. Biogerontology 12, 467–471 (2011). https://doi.org/10.1007/s10522-011-9350-7
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DOI: https://doi.org/10.1007/s10522-011-9350-7