Skip to main content

Advertisement

Log in

Biogerontology in Russia: from past to future

  • Original Paper
  • Published:
Biogerontology Aims and scope Submit manuscript

Abstract

The paper presents major steps of gerontology development in Russia. The issues of training in gerontology and geriatrics, institutional infrastructure within the Gerontological Society of the Russian Academy of Sciences and its activities have been considered therein. Some results of Russian researchers obtained during 2005–2010 have been summarized as well. Special attention is given to the prospects of gerontology in Russia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Abbreviations

IBCP:

N.M. Emanuel Institute of Biochemical Physics, RAS

ICP:

Institute of Chemical Physics, RAS

IGC:

Institute of Genetics and Cytology, Siberian Branch of the RAS

IPCB:

A.N. Belozersky Institute of Physical and Chemical Biology

IPCP:

Institute of Problems of Chemical Physics, RAS

RAMS:

The Russian Academy of Medical Sciences

RAS:

The Russian Academy of Sciences

RIEM:

Research Institute of Experimental Medicine, RAMS

RIOG:

D.O. Ott Research Institute of Obstetrics and Gynecology, RAMS

SMC-CVSRS:

Scientific-Medical Center of the Committee of Veterans of Special Risk Subdivisions in Russian Federation

SPb:

Saint-Petersburg

SPb IBG RAMS:

St. Petersburg Institute of Bioregulation and Gerontology, North-Western Branch RAMS

References

  • Abatnina JV, Bazhanova ED, Teply DL (2005) Role of vitamin E in regulation apoptosis at pathology and aging. Adv Gerontol 17:29–33

    Google Scholar 

  • Alimova IN, Liu B, Fan Z, Edgerton SM, Dillon T, Lind SE, Thor AD (2009) Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro. Cell Cycle 8:909–915

    Article  PubMed  CAS  Google Scholar 

  • Alishev NV, Vashkevich AA, Drabkin BA, Koroleva TM, Kosickaya LS, Shubik VM (2007) Accelerated aging of immune system of the veterans of special risk subdivisions. Adv Gerontol 20:96–111

    PubMed  CAS  Google Scholar 

  • Alishev NV, Drabkin BA, Shubik VM (2010) Stress-immunity-health (problem of precocious aging in veterans of special risk subdivisions). Adv Gerontol 23:49–55

    PubMed  CAS  Google Scholar 

  • Anisimov VN (2001) Experimental research on ageing in Russia. Exp Gerontol 26:935–946

    Article  Google Scholar 

  • Anisimov VN (2005) Biological interactions of aging and carcinogenesis. Cancer Treat Res 124:17–50

    Article  PubMed  Google Scholar 

  • Anisimov VN (2006a) Effect of host age on tumor growth rate in rodents. Front Biosci 11:412–422

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN (2006b) Light pollution, reproductive function and cancer risk. Neuro Endocrinol Lett 27:35–52

    PubMed  CAS  Google Scholar 

  • Anisimov VN (2006c) Premature ageing prevention: limitations and perspectives of pharmacological interventions. Curr Drugs Targets 7:1485–1503

    CAS  Google Scholar 

  • Anisimov VN (2007) Biology of aging and cancer. Cancer Control 14:23–31

    PubMed  Google Scholar 

  • Anisimov VN (2008) Antidiabetic drugs in aging and cancer: results and perspectives. Open Aging J 2:36–48

    CAS  Google Scholar 

  • Anisimov VN (2009) Carcinogenesis and aging 20 years after: escaping horizon. Mech Ageing Dev 130:105–121

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Khavinson VKh (2010) Peptide bioregulation of aging: results and prospects. Biogerontology 11:139–149

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Khavinson VKh (2003) Small peptide-associated modulation of aging and longevity. In: Rattan SIS (ed) Modulating aging and longevity. Kluwer Academic Publishers, Dordrecht, pp 279–301

  • Anisimov VN, Khavinson VKh (2005) Pineal peptides as modulators of aging. In: Rattan SIS (ed) Aging interventions and therapies. World Scientific, Singapore, pp 127–146

  • Anisimov VN, Khavinson VKh, Mikhalski AI, Yashin AI (2001) Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice. Mech Ageing Dev 122:41–68

    Article  PubMed  CAS  Google Scholar 

  • Anisimov SV, Boheler KR, VKh Khavnson, Anisimov VN (2002a) Studies of the effects of Vilon and Epithalamin ongene expression in mouse heart using DNA-microarray technology. Bull Exp Biol Med 133:293–299

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Khavinson VKh, Provinciali M, Alimova IN, Baturin DA, Popovich IG, Zabezhinski MA, Imyanitov EN, Mancini R, Franceschi C (2002b) Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in Her-2/NEU transgenic mice. Int J Cancer 101:7–10

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, Zavarzina NYu, Semenchenko AV, Yashin AI (2003) Effect of epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. 4:193–202

  • Anisimov SV, Boheler KR, Khavinson VKh, Anisimov VN (2004) Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray. Neuro Endocrinol Lett 25:87–93

    PubMed  CAS  Google Scholar 

  • Anisimov VN, Berstein LM, Egormin PA, Piskunova TS, Popovich IG, Zabezhinski MA, Kovalenko IG, Poroshina TE, Semenchenko AV, Provinciali M, Re F, Franceschi C (2005) Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Exp Gerontol 40:685–693

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Popovich IG, Zabezhinski MA, Anisimov SV, Vesnushkin GM, Vinogradova IA (2006) Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta 1757:573–589

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Popovich IG, Zabezhinski MA (2007) Methods of evaluating the effect of pharmacological drugs on aging and life span in mice. Methods Mol Biol 371:227–236

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Baranov VS, Khavinson VKh, Kozlov LV, Mikhailova ON, Ryzhak GA, Kvetnoy IM, Kvetnaya TV, Malinin VV (2008a) Programme for prevention of age-related pathology and accelerated ageing, reduction of premature mortality due to biological reasons and extension of healthy period of life for the population of Russia. KOSTA, St. Petersburg, 72 pp

  • Anisimov VN, Berstein LM, Egormin PA, Piskunova TS, Popovich IG, Zabezhinski MA, Tyndyk ML, Yurova MV, Kovalenko IG, Poroshina TE, Semenchenko AV (2008b) Metformin slows down aging and extends life span of female SHR mice. Cell Cycle 7:2769–2773

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Sikora E, Pawelec G (2009) Relationships between cancer and aging: multilevel approach. Biogerontology 10:323–338

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Egormin PA, Piskunova TS, Popovich IG, Tyndyk ML, Yurova MV, Zabezhinski MA, Anikin IV, Karkach AS, Romanyukha AA (2010a) Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle 9:188–197

    Article  PubMed  CAS  Google Scholar 

  • Anisimov VN, Zabezhinski MA, Popovich IG, Piskunova TS, Semenchenko AV, Tyndyk ML, Yurova MV, Antoch MP, Blagosklonny MV (2010b) Rapamycin extends maximal life span in cancer-prone mice. Am J Pathol 176:2092–2097

    Article  PubMed  CAS  Google Scholar 

  • Babizhaev MA, Yegorov YE (2010) Telomere attrition in lens epithelial cells—a target for N-acetylcarnosine therapy. Front Biosci 15:934–956

    Article  Google Scholar 

  • Baranov VS, Baranova EV (2007) Genetic aspects of ageing. Adv Gerontol 20(2):26–34

    PubMed  CAS  Google Scholar 

  • Bashkireva AS, Khavinson VKh (2007) Occupational risk of accelerated ageing in motor transport drivers. Med Tr Prom Ekol 11:13–21

    PubMed  Google Scholar 

  • Bashkireva AS, Artamonova VG, Khavinson VKh (2009) Productive aging or “healthy worker effect”? Retrospective analysis of morbidity with temporal workability loss in motor transport driver. Adv Gerontol 22:539–547

    PubMed  CAS  Google Scholar 

  • Batin M, Moskalev A, Novoseltsev V, Michalski A, Tereshina E. (2009) “Science against aging”—a complex interdisciplinary program of fundamental research. PA6 047. J Nutr Health Aging 13(Suppl 1):S218

    Google Scholar 

  • Berstein LM (2005) Clinical usage of hypolipidemic and antidiabetic drugs in the prevention and treatment of cancer. Cancer Lett 224:203–212

    Article  PubMed  CAS  Google Scholar 

  • Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM Jr, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J (2010) Impact papers on aging in 2009. Aging (Albany NY) 2:111–121

    CAS  Google Scholar 

  • Boldyrev AA, Stvolinsky SL, Fedorova TN, Suslina ZA (2010) Carnosine as a natural antioxidant and geroprotector: from molecular mechanisms to clinicl trials. Rejuvenation Res 13:156–158

    Article  PubMed  CAS  Google Scholar 

  • Butov AA, Volkov MA, Anisimov VN, Yashin AI (2002) A model of accelerated aging induced by 5-bromodeoxyuridine. Biogerontology 3:175–182

    Article  PubMed  CAS  Google Scholar 

  • De Luca M, Roshina NV, Geiger-Thornsberry GL, Lyman RF, Pasyukova EG, Mackay TF (2003) Dopa decarboxylase (Ddc) affects variation in Drosphila longevity. Nat Genet 34:429–433

    Article  PubMed  Google Scholar 

  • Demyanov VF (2005) A mathematical model of the evolution and aging. Adv Gerontol 17:18–28

    Google Scholar 

  • Deriabina ON, Plotnikova NA, Anisimov VN (2010a) Melatonin and metformin inhibit benz(a)pyrene-induced skin carcinogenesis in mice. Vopr Onkol (in press)

  • Deriabina ON, Plotnikova NA, Kharitonova TV, Kirichenko EV, Soldatov IV, Anisimov VN (2010b) Melatonin and metformin inhibit benz(a)pyrene-induced cervico-vaginal carcinogenesis in mice. Morphol Vedomosti (in press)

  • Dilman VM (1971) Age-associated elevation of hypothalamic threshold to feedback control and its role in development, aging and disease. Lancet 1:1211–1219

    Article  PubMed  CAS  Google Scholar 

  • Dilman VM, Anisimov VN (1980) Effect of treatment with phenfromin, dyphenylhydantoin or L-DOPA on life span and tumor incidence in C3H/Sn mice. Gerontology 26:241–245

    Article  PubMed  CAS  Google Scholar 

  • Duplenko Yu K (1985) Aging. The essay of the problem development. Nauka, Leningrad, 192 pp

  • Evans JM, Donnelly LA, Emslie-Smith AM, Alessi DR, Morris AD (2005) Metformin and reduced risk of cancer in diabetic patients. BMJ 330:1304–1305

    Article  PubMed  Google Scholar 

  • Gladyshev GP (2005) The second law of thermodynamics and the evolution of living systems. J Human Thermodyn 1:68–81

    Google Scholar 

  • Gladyshev GP (2006) The principle of substance stability is applicable to all levels of organization of living matter. Int J Mol Sci 7:98–110

    Article  CAS  Google Scholar 

  • Glotov OS, Baranov VS (2007) Genetic polymorphism and aging. Adv Gerontol 20(2):35–54

    PubMed  CAS  Google Scholar 

  • Golubev AG (2009a) The issue of feasibility of a general theory of aging. I. Generalized Gompeertz–Makeham law. Adv Gerontol 22:60–73

    PubMed  CAS  Google Scholar 

  • Golubev AG (2009b) The issue of feasibility of a general theory of aging. II. The parametabolic theory of aging. Adv Gerontol 22:205–222

    PubMed  CAS  Google Scholar 

  • Goncharova ND, Vengerin AA, Khavinson VKh, Lapin BA (2005) Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreas. Exp Gerontol 40:51–57

    Article  PubMed  CAS  Google Scholar 

  • Goncharova ND, Shmaliy AV, Bogatyrenko TN, Koltover VK (2006) Correlation between activity of antioxidant enzymes and circadian rhythms of corticseroids in Macaca mulatta monkeys of different age. Exp Gerontol 41:778–783

    Article  PubMed  CAS  Google Scholar 

  • Goncharova ND, Shmaliy AV, Marenin VY, Smelkova SA, Lapin BA (2008) Circadian and age-related changes in stress resposiveness of the adrenal cortex and erythrocyte antioxidant enzymes in female rhesus monkey. J Med Primatol 37:229–238

    Article  PubMed  Google Scholar 

  • Imyanitov EN (2009) Use of elderly tumor-free subjects as a “supercontrol” for cancer epidemiological studies: pros and cons. Mech Ageing Dev 130:122–127

    Article  PubMed  Google Scholar 

  • Khavinson VKh (2002) Peptides and ageing. Neuro Endocrinol Lett 23(Suppl 3. special issue):11–144

  • Khavinson VKh, Malinin VV (2005) Gerontological aspects of genome peptide regulation. Karger AG, Basel (Switzerland), 104 pp

  • Khavinson VKh, Mikhailova ON (2007) Health and aging in Russia. In: Robinson M, Novelli W, Pearson C, Norris L (eds) Global health and global aging. AARP Foundation, Jossey-Bass, USA, pp 226–237

  • Khavinson VKh, Goncharova N, Lapin B (2001) Synthetic tetrapeptide epitalon restores disturbed neuroendocrine regulation in senescent monkeys. Neuro Endocrinol Lett 22:251–254

    PubMed  CAS  Google Scholar 

  • Khavinson V, Razumovsky M, Trofimova S, Grigorian R, Razumovskaya A (2002) Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa. Neuro Endocrinol Lett 23:365–368

    PubMed  CAS  Google Scholar 

  • Khavinson VKh, Lezhava TA, Monaselidze JR, Jokhadze TA, Dvalis NA, Bablishvili NK, Trofimova SV (2003) Peptide Epitalon activates chromatin at the old age. Neuro Endocrinol Lett 24:329–333

    PubMed  CAS  Google Scholar 

  • Khavinson V, Bondarev I, Butyugov A (2004a) Epitalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med 135:590–592

    Article  Google Scholar 

  • Khavinson V, Bondarev I, Butyugov A, Smirnova T (2004b) Peptide promotes overcoming of the division limit in human somatic cell. Bull Exp Biol Med 137:613–616

    Google Scholar 

  • Khavinson V, Shataeva L, Chernova A (2005) DNA double-helix binds regulatory peptides similarly to transcription factors. Neuro Endocrinol Lett 26:237–241

    PubMed  CAS  Google Scholar 

  • Khavinson VKh, Solovyov AY, Shataeva LK (2008) Melting of DNA double strand after binding to geroprotective tetrapeptide. Bull Exp Biol Med 146:624–626

    Article  PubMed  CAS  Google Scholar 

  • Koltover VK (2009) Bioantioxidants: the systems reliability standpoint. Toxicol Ind Health 25:295–299

    Article  PubMed  CAS  Google Scholar 

  • Kosarev VV, Babanov SA, Gaydisn PV (2009) The problem of premature senescence in professional diseases of lungs. Adv Gerontol 22:660–661

    PubMed  CAS  Google Scholar 

  • Kossoy G, Zandbank J, Tendler E, Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA, Zusman I, Ben-Hur H (2003) Epitalon and colon carcinogenesis in rats: proliferative activity and apoptosis in colon tumors and mucosa. Int J Mol Med 12:473–477

    PubMed  CAS  Google Scholar 

  • Kozina LS, Arutjunyan AV, Khavinson VKh (2007) Antioxidant properties of geroprotective peptides of the pineal gland. Arch Gerontol Geriatr 44(Suppl 1):213–216

    Google Scholar 

  • Kudryavtseva TK (ed) (2007a) Gerontology and geriatrics. Bibliography of publications of Russian researchers in 1994–2006. St. Petersburg

  • Kudryavtseva TK (ed) (2007b) Gerontology and geriatrics. Contribution of Russia to world gerontology. Bibliography of publications of Russian researchers in International Monographs and Journals, 1994–2006. St. Petersburg

  • Liu B, Fan Z, Edgerton SM, Deng XS, Alimova IN, Lind SE, Thor AD (2009) Metformin induces unique biological and molecular responses in triple negative breast cancer cells. Cell Cycle 8:2031–2040

    Article  PubMed  CAS  Google Scholar 

  • Magwire MM, Yamamoto A, Carbone MA, Roshina NV, Symonenko AV, Pasyukova EG, Morozova TV, Mackay TF (2010) Quantitative and molecular genetic analyses of mutations increasing Drosphila life span. PLoS Genet 6(7):e1001037

    Article  PubMed  Google Scholar 

  • Makrushin AV (2008) Is the mankind under the threat of extinction? Adv Gerontol 21:353–355

    PubMed  CAS  Google Scholar 

  • Mamaev VB, Tsarin AA (2007) Historical dynamics of age-related mortality. 2. Sexual dimorphism and calculation issues. Adv Gerontol 20:20–28

    PubMed  CAS  Google Scholar 

  • Marchuk GI, Anisimov VN, Romaniukha AA, Yashin AI (2007) Gerontologia in silico: establishment of a new discipline. Mathematical models, data analysis and calculation expreiments. BINOM, Laboratory of Knowledge, Moscow, 535 pp

  • Martin-Castillo B, Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA (2010) Metformin and cancer. Doses, mechanisms and the dandelion and hermetic phenomena. Cell Cycle 9:1057–1064

    Article  CAS  Google Scholar 

  • Mikhailova ON, Anisimov VN, Sidorenko AV (2005) Development of gerontology in Russia: the Role of International Collaboration, Firm Kosta, St. Petersburg

  • Mikhalski AI, Novoseltsev VN (2005) Quantitative analysis and modeling of aging, disability and mortality. Adv Gerontol 17:117–129

    Google Scholar 

  • Moldaver MV, Yegorov YE (2009) Sparse plating increases the heterogeneity of proliferative potential of fibroblasts. Mech Ageing Dev 130:337–342

    Article  PubMed  Google Scholar 

  • Moskalev AA (2008) About genetic determinants of aging pathways. Adv Gerontol 21:463–469

    PubMed  CAS  Google Scholar 

  • Moskalev AA (2010) Evolution conception about the aging nature. Adv Gerontol 23:9–20

    PubMed  CAS  Google Scholar 

  • Moskalev AA, Plyusnina EN (2007) Drosophila melanogaster recessive lethal mutation in X-chromosome locus 6d1–7a2 in heterozygote leads to life span increasing. Adv Gerontol 20(4):36–39

    PubMed  CAS  Google Scholar 

  • Moskalev AA, Shaposhnikov MV (2010) Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster. Rejuvenation Res 13:246–247

    Article  PubMed  CAS  Google Scholar 

  • Obukhova LA, Skulachev VP, Kolosova NG (2009) Mitochondria-targeted antioxidant SkQ inhibits age-dependent involution of the thymus in normal and senescence-prone rats. Aging (Albany NY) 1:389–401

    CAS  Google Scholar 

  • Olovnikov AM (2007) Hypothesis: lifespan is regulated by chronomere DNA of the hypothalamus. J Alzheimers Dis 11:241–252

    PubMed  CAS  Google Scholar 

  • Pauk VV, Nasibullin TR, Tuktarova IA, Zueva LP, Mustafina OE (2008) Antioxidant gene polymorphism in connection with life span. Adv Gerontol 21:593–595

    PubMed  CAS  Google Scholar 

  • Pirozhkov SI, Safarova GL, Schebrov SY (2007) Population ageing in Russia and Ukraine: look into future. Adv Gerontol 20(2):14–22

    PubMed  CAS  Google Scholar 

  • Piskunova TS, Yurova MN, Zabezhinski MA, Anisimov VN (2007) Poly(ADP-ribosa)polymerase—the relationship with life span and carcinogenesis. Adv Gerontol 20(2):82–90

    PubMed  CAS  Google Scholar 

  • Piskunova TS, Yurova MN, Ovsjannikov AI, Semenchenko AV, Zabezhinski MA, Popovich IG, Wang Z-Q, Anisimov VN (2008) Deficiency in poly(ADP-ribose) polymerase-1 (PARP-1) accelerates aging and spontaneous carcinogenesis in mice. Current Gerontol Geriatr Res Vol 2008, Article ID 754190, 11 pp. doi:10.1155/2008/754190

  • Polubotko EA, Shatrova AN, Pleskach NM, Mikhelson VM, Spivak IM (2009) Cellular repair potential in families of ataxia-telangiectasia patients. Tsitologiia 51:978–985

    PubMed  CAS  Google Scholar 

  • Popov IY (2008) Species senescence: facts or illusion? Adv Gerontol 21:181–194

    PubMed  Google Scholar 

  • Pospelova TV, Demidenko ZH, Bukreeva EI, Pospelov VA, Gudkov AV, Blagosklonny MV (2009) Pseudo-DNA damage response in senescent cells. Cell Cycle 8:4112–4118

    Article  PubMed  CAS  Google Scholar 

  • Rybina OY, Pasyukova EG (2010) A naturally occurring polymorphism at Drosophila melanogaster Lim3 Locus, a homolog of human LHX3/4, affects Lim3 transcription and fly lifespan. PLoS One 5(9):e12621

    Article  PubMed  Google Scholar 

  • Safarova GL, Kosolapenko NV, Atutionov VA (2005) Regional differentiation of ageing in Russia. Adv Gerontol 16:7–13

    PubMed  CAS  Google Scholar 

  • Schwartzburd PM (2008) Stem cells and precancer inflammatory conditions in development of age-specific cancer. Adv Gerontol 21:356–366

    Google Scholar 

  • Severin FF, Skulachev VP (2009) Programmed cell death as a target to interrupt the aging program. Adv Gerontol 22:37–47

    PubMed  CAS  Google Scholar 

  • Shnitnikova OA, Kopylova LV, Chernyak EI, Morozov SV, Kolosova NG, Tsentalovich YP (2009) Tryptophan and kynureninelevels in lenses of Wistar and accelerated-senescence OXYS rats. Mol Vis 15:2780–2788

    Google Scholar 

  • Shram SI, Shilovskii GA, Khokhlov AN (2006) Poly(ADP-ribose)-polymerase-1 and aging: experimental study of possible relationship on stationary cell culture. Bull Exp Biol Med 141:628–632

    Article  PubMed  CAS  Google Scholar 

  • Skulachev VP (2009) New data on biochemical mechanism of programmed senescence of organisms and antioxidant defense of mitochondria. Biochemistry (Moscow) 74:1400–1403

    Article  CAS  Google Scholar 

  • Skulachev VP, Anisimov VN, Antonenko YN, Bakeeva LE, Chernyak BV, Erichev VP, Filenko OF, Kalinina NI, Kapelko VI, Kolosova NG, Kopnin BP, Korshunova GA, Lichinitser MR, Obukhova LA, Pasuykova EG, Pisarenko OI, Roginsky VA, Ruuge EK, Senin II, Severina II, Skulachev MV, Spivak IM, Tashlimsky VN, Tkachuk VA, Vyssokikh MYu, Yaguzhinsky LS, Zorov DB (2009) An attempt to prevent senescence: a mithochondrial approach. Biochim Biphys Acta 1787:437–461

    Article  CAS  Google Scholar 

  • Smirnova NV, Spivak IM, Pleskach NM, Zherebtsov SV, Aksenov NL, Mikhelson VM (2008) An atypical case of Werner syndrome: epiogenetic control and DNA damage response allterations. Tsitologiia 50:868–876

    PubMed  CAS  Google Scholar 

  • Stevens RG (2009) Light-at-night, circadian disruption and breast cancer: assessment of existing evidence. Int J Epidemiol 38:963–970

    Article  PubMed  Google Scholar 

  • Straif K, Baan R, Grosse Y et al (2007) Carcinogenicity of shift-work, painting, and fire-fighting. Lancet Oncol. 8:1065–1066

    Article  PubMed  Google Scholar 

  • Tatarinova OV, Nikitin YP (2008) Some demographic indices of the aging and longevity in Yakutia. Adv Gerontol 21:526–534

    Google Scholar 

  • Tatarinova OV, Kylbanova ES, Neustroeva VN, Semenova AN, Nikitin YP (2008) Phenomenon of supercentenarian in Yakutia. Adv Gerontol 21:198–203

    PubMed  CAS  Google Scholar 

  • Vinogradova IA, Anisimov VN, Bukalev AV, Semenchenko AV, Zabezhinski MA (2009) Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in rats. Aging 1:855–865

    PubMed  CAS  Google Scholar 

  • Yashin AI, Romanioukha AA, Mikhalski AI, Novoseltsev VN, Ukraintseva SV, Khalyavkin AV, Anisimov VN (2007) Gerontology in silico: the emergence of a new discipline. Adv Gerontol 20:7–19

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vladimir N. Anisimov.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Anisimov, V.N., Khavinson, V.K. & Mikhailova, O.N. Biogerontology in Russia: from past to future. Biogerontology 12, 47–60 (2011). https://doi.org/10.1007/s10522-010-9307-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10522-010-9307-2

Keywords

Navigation