Abstract
Offspring from Drosophila melanogaster populations of different maternal age were derived and aged. Our results showed that offspring longevities do not follow inversely the mother’s ages i.e., increasing age of the mothers do not result in decreased offspring mean longevities in general (no typical Lansing effect). We found that also each population has distinct offspring age specific mortality rates with increasing maternal age. Overall, we suggest, this may point to unique genetic background effect of each particular population has on longevities within context of maternal age, considering that populations studied would signify distinct genetic variation states of samples of different geographic origin.
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References
Bozcuk AN (1981) Genetics of longevity in Drosophila V. The specific and hybridised effects of rolled, sepia, ebony and eyeless autosomal mutants. Exp Gerontol 16:415–427
Falconer DS, Mackay TFC (1996) Quantitative Genetics. Longman, England, 464 pp
Geiger-Thornsberry GL, Mackay TFC (2004) Quantitative trait loci affecting natural variation in Drosophila longevity. Mech Ageing Dev 125:179–189
Lansing AI (1947) A transmissible, cumulative, and reversible factor in aging. J Gerontol 2:228–239
Lansing AI (1948) Evidence for aging as a consequence of growth cessation. PNAS USA 34:304–310
Lansing AI (1954) A nongenetic factor in the longevity of rotifers. Ann NY Acad Sci 57:455–464
Lints FA (1971) Life span in Drosophila. Gerontologia 17:33–51
Lints FA, Hoste C (1974) The Lansing effect revisited-I. Life span. Exp Gerontol 9:51–69
Mackay TFC (2001) The genetic architecture of quantitative traits. Annu Rev Genet 35:303–339
Mackay TFC (2002) The nature of quantitative genetic variation for Drosophila longevity. Mech Aging Dev 123:95–104
Nuzhdin SV, Pasyukova EG, Dilda CL, Zeng ZB (1997) Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster. Proc Natl Sci USA 94:9734–9739
Nuzhdin SV, Khazaeli AA, Curtsinger JW (2005) Survival analysis of life span quantitative trait loci in Drosophila melanogaster. Genetics 170:719–731
Pasyukova EG, Roshina NV, Mackay TFC (2004) Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan. Aging Cell 3:297–307
Pletcher SD (1999) Model fitting and hypothesis testing for age-specific data. J Evol Biol 12:430–439
Priest NK, Mackowiak B, Promislow DEL (2002) The role of parental age effects on the evolution of aging. Evolution 56:927–935
Rollmann SM, Magwire MM, Morgan TJ, Özsoy ED, Yamamoto A, Mackay TFC, Anholt RRH. 2006. Pleiotropic fitness effects of the Tre1/Gr5a region in Drosophila. Nat Genet 38:824–829
Soliman MH (1987) Ageing and parental age effects in Tribolium. Arch Gerontol Geriatr 6:43–60
Spencer CC, Promislow DEL (2005) Age-specific changes in epistatic effects on mortality rate in Drosophila melanogaster. J Hered 96:513–521
Verdone-Smith C, Enesco HE (1982) Maternal age and life span do not influence longevity in the rotifer Asplancha brightwelli. Exp Gerontol 17:263–266
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We thank to two anonymous reviewers for their valuable contributions to improve the first version of the manuscript.
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Yılmaz, M., Özsoy, E.D. & Bozcuk, A.N. Maternal age effects on longevity in Drosophila melanogaster populations of different origin. Biogerontology 9, 163–168 (2008). https://doi.org/10.1007/s10522-008-9125-y
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DOI: https://doi.org/10.1007/s10522-008-9125-y