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Genetic Basis Underlying Behavioral Correlation Between Fugu Takifugu rubripes and a Closely Related Species, Takifugu niphobles

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Abstract

Correlated suits of behaviors (behavioral syndrome) are commonly observed in both inter- and intraspecific studies. In order to understand the genetic basis of such a correlation between species, we compared ten behaviors classified into five categories (acclimation, feeding, normal swimming, reaction to a novel object and activity in a novel environment) between two pufferfish species, Takifugu rubripes and T. niphobles. The two species showed consistent differences in nine behaviors with a significant correlation among behaviors. Quantitative trait locus (QTL) analysis using second generation hybrids revealed that different sets of small effect QTL are associated with the observed interspecific behavioral disparity. This indicates that correlations in temperament traits between them are governed by many genes with small effects, and each behavior has been selected to form particular combination patterns. One of the QTL showing small pleiotropic effect includes the Drd4 gene known for its association with behavioral traits in some animal taxa including mammals.

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Acknowledgments

The authors thank Naoki Mizuno, Yuka Jo and Masashi Fujita (University of Tokyo) for technical support. This research was funded by Grants-in-Aid for Scientific Research, Japanese Society for the Promotion of Science (to S.H., H.S., Y.S. and K.K.).

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The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

All institutional and national guidelines for the care and use of laboratory animals were followed.

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Authors and Affiliations

  1. Fisheries Laboratory, Graduate School of Agricultural and Life Sciences, University of Tokyo, 2971-4, Bentenjima, Maisaka, Shizuoka, Hamamatsu, 431-0214, Japan

    Sho Hosoya, Yuzuru Suzuki & Kiyoshi Kikuchi

  2. Department of Marine Bioscience, Fukui Prefectural University, Obama, Fukui, 917-0003, Japan

    Hiroaki Suetake

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  1. Sho Hosoya
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  2. Hiroaki Suetake
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  4. Kiyoshi Kikuchi
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Correspondence to Sho Hosoya.

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Hosoya, S., Suetake, H., Suzuki, Y. et al. Genetic Basis Underlying Behavioral Correlation Between Fugu Takifugu rubripes and a Closely Related Species, Takifugu niphobles . Behav Genet 45, 560–572 (2015). https://doi.org/10.1007/s10519-015-9728-4

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