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Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia

  • GENERAL PATHOLOGY AND PATHOPHYSIOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

The effect of phenolic antioxidants (dihydroquercetin, p-tyrosol, dibornol) on the morphology, functions, and redox processes in the reproductive cells of male rats was studied on the model of experimental pathospermia. All antioxidants reduced the percentage of degenerative forms of spermatozoa. Dibornol was most effective. Dihydroquercetin and p-tyrosol did not increase the total number of spermatozoa and the percentage of their mobile forms. These indicators were improved only by dibornol. After administration of all test drugs, the antioxidant potential of spermatozoa increased and did not significantly differ from the baseline values.

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Correspondence to T. G. Borovskaya.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 166, No. 7, pp. 10-13, July, 2018

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Borovskaya, T.G., Kamalova, S.I., Krivova, N.A. et al. Experimental Study of the Effectiveness of Phenolic Antioxidants in Male Infertility Caused by Pathospermia. Bull Exp Biol Med 166, 7–10 (2018). https://doi.org/10.1007/s10517-018-4276-6

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  • DOI: https://doi.org/10.1007/s10517-018-4276-6

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