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Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

  • IMMUNOLOGY AND MICROBIOLOGY
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Bulletin of Experimental Biology and Medicine Aims and scope

We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.

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Authors and Affiliations

  1. Research Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia

    A. P. Lykov, N. A. Bondarenko, M. A. Surovtseva, I. I. Kim, O. V. Poveshchenko, E. A. Pokushalov & V. I. Konenkov

  2. E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia

    A. P. Lykov, N. A. Bondarenko, M. A. Surovtseva, I. I. Kim, O. V. Poveshchenko & E. A. Pokushalov

Authors
  1. A. P. Lykov
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  2. N. A. Bondarenko
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  3. M. A. Surovtseva
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  4. I. I. Kim
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  5. O. V. Poveshchenko
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  6. E. A. Pokushalov
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  7. V. I. Konenkov
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Correspondence to A. P. Lykov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 163, No. 6, pp. 722-725, June, 2017

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Lykov, A.P., Bondarenko, N.A., Surovtseva, M.A. et al. Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells. Bull Exp Biol Med 163, 757–760 (2017). https://doi.org/10.1007/s10517-017-3897-5

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  • DOI: https://doi.org/10.1007/s10517-017-3897-5

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