We studied the frequency of alleles and genotypes of CAT gene -262C>T polymorphism (rs1001179) in Russian and Buryat adolescents. The frequency of -262T allele was 28.31% in Russians and 16.84% in Buryats (p<0.01). In both ethnic groups, a correlation between the study polymorphism and concentration of diene conjugates was observed. Carriers of TT-genotype of CAT gene-262C>T polymorphism had lower level of diene conjugates than carriers of CT- and CC-genotypes.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 161, No. 3, pp. 378-381, March, 2016
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Ershova, O.A., Bairova, T.A., Kolesnikov, S.I. et al. Oxidative Stress and Catalase Gene. Bull Exp Biol Med 161, 400–403 (2016). https://doi.org/10.1007/s10517-016-3424-0
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DOI: https://doi.org/10.1007/s10517-016-3424-0