The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The effi cacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells in the recovery of antitumor regulatory mechanisms was estimated.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 157, No. 2, pp. 223-226, February, 2014
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Bocharova, O.A., Bocharov, E.V., Karpova, R.V. et al. Integrins LFA-1 and Mac-1 and Cytokines IL-6 and IL-10 in High-Cancer Mice under the Influence of Phytoadaptogen. Bull Exp Biol Med 157, 258–260 (2014). https://doi.org/10.1007/s10517-014-2539-4
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DOI: https://doi.org/10.1007/s10517-014-2539-4