We studied the key parameters of the development of prediabetic state in rats maintained on a high-calorie diet. It was found that long-term feeding a high-calorie diet increased blood concentration of glucose, glycosylated hemoglobin, and insulin and reduced the rate of glucose uptake in comparison with rats receiving standard ration.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 156, No. 11, pp. 582-585, November, 2013
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Karpovets, T.P., Konopelnyuk, V.V., Galenova, T.I. et al. High-Calorie Diet as a Factor of Prediabetes Development in Rats. Bull Exp Biol Med 156, 639–641 (2014). https://doi.org/10.1007/s10517-014-2414-3
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DOI: https://doi.org/10.1007/s10517-014-2414-3