Skip to main content
SpringerLink
Log in

Possible Aspects of Using Cultured Stem Cell of Laboratory Primates in Experimental Medicine

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

We describe the methods of isolation and culturing of mesenchymal stem cells from 3 monkey species Macaca mulatta, Papio hamadryas, and Macaca fascicularis. Flow cytofl uorometry showed that the cells do not express CD34, CD45, and HLA-DR, but most of them (78-98%) express CD90 marker. The cardioprotective effects of cultured mesenchymal stem cells in cardiomyopathy induced by administration of antitumor anthracycline drugs (doxorubicin).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. A. Ivanov, Biology of Stem Cells and Cell Technologies, Ed. M. A. Pal’tsev [in Russian], Moscow (2009), Vol. 1, pp. 31-43.

  2. N. I. Kalinina, F. Yu. Ufi menko, T. V. Lopatina, et al., Autologous Stem Cells. Experimental Studies and Prospects of Cli nical Application [in Russian], St. Petersburg (2009), pp. 74-85.

  3. M. A. Pal’tsev, A. A. Ivanov, V. N. Smirnov, and Yu. A. Romanov, Molekul. Med., No. 2, 5-9 (2006).

  4. Yu. A. Romanov and V. N. Smirnov, Biology of Stem Cells and Cell Technologies [in Russian], Moscow (2009), pp. 193-205.

  5. A. F. Tsyb, A. G. Konoplyannikov, A. I. Kolesnikova, and V. V. Pavlov, Vestn. Ross. Akad. Med. Nauk., No. 9, 71-76 (2004).

  6. V. I. Shumakov, N. A. Onishchenko, M. E. Krisheninnikov, et al., Vestn. Ross. Akad. Med. Nauk., No. 9, 44-47 (2004).

  7. V. I. Shumakov, O. P. Shevchenko, O. B. Onishchenko, S. V. Gureev, et al., Molekul. Med., No. 2, 48-54 (2006).

  8. M. Dominici, K. Le Blanc, I. Mueller, et al., Cytotherapy, 8, No. 4, 315-317 (2006).

    Article  PubMed  CAS  Google Scholar 

  9. K. Fukuda, Artif. Organs, 25, No. 3, 187-193 (2001).

    Article  PubMed  CAS  Google Scholar 

  10. B. Puissant, C. Barreau, P. Bourin, et al., Br. J. Haematol., 129, No. 1, 118-129 (2005).

    Article  PubMed  Google Scholar 

  11. K. McIntosh, S. Zvonic, S. Garrett, et al., Stem Cells, 24, No. 5, 1246-1253 (2006).

    Article  PubMed  CAS  Google Scholar 

  12. Y. S. Yoon, J. S. Park, T. Tkebuchava, et al., Circulation, 109, No. 25, 3154-3157 (2004).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Research Institute of Medical Primatology, Russian Academy of Medical Sciences, Sochi, Russia

    V. Z. Agrba, D. D. Karal-ogly, I. E. Ignatova, T. E. Gvozdik, A. A. Agumava, A. V. Leontiuk & B. A. Lapin

  2. S. V. Ochapovsky Regional Clinical Hospital No. 1, Krasnodar, Russia

    V. A. Porkhanov

  3. Medical Radiological Research Center, Ministry of Health and Social Development of the Russian Federation, Obninsk, Russia

    A. G. Konoplyannikov & S. Sh. Kal’sina

Authors
  1. V. Z. Agrba
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. A. Porkhanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. G. Konoplyannikov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. Sh. Kal’sina
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. D. Karal-ogly
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. I. E. Ignatova
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. T. E. Gvozdik
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. A. A. Agumava
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. A. V. Leontiuk
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. B. A. Lapin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. Z. Agrba.

Additional information

Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 3, pp. 139-142, July, 2012

Rights and permissions

Reprints and permissions

About this article

Cite this article

Agrba, V.Z., Porkhanov, V.A., Konoplyannikov, A.G. et al. Possible Aspects of Using Cultured Stem Cell of Laboratory Primates in Experimental Medicine. Bull Exp Biol Med 154, 133–135 (2012). https://doi.org/10.1007/s10517-012-1893-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-012-1893-3

Keywords

Search

Navigation