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Effect of Opioid Peptides on the Content of LPO Products and Antioxidant Enzyme Activity in the Liver of Rats after Restraint Stress

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Bulletin of Experimental Biology and Medicine Aims and scope

Administration of opioid peptides dynorphin A (1-13) and DSLET was followed by a decrease in the stress-induced activation of LPO and increase in SOD activity in the liver tissue of rats. DAGO produced a similar, but less pronounced effect. The observed changes can be related to a specific distribution of opioid receptors in the liver tissue and stress-limiting influence of these peptides in the whole body.

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Authors and Affiliations

  1. Department of Pathophysiology, Kursk State Medical University, Ministry of Health and Social Development of the Russian Federation, Kursk, Russia

    A. V. Solin & Yu. D. Lyashev

Authors
  1. A. V. Solin
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  2. Yu. D. Lyashev
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Correspondence to A. V. Solin.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 153, No. 6, pp. 803–805, June, 2012

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Solin, A.V., Lyashev, Y.D. Effect of Opioid Peptides on the Content of LPO Products and Antioxidant Enzyme Activity in the Liver of Rats after Restraint Stress. Bull Exp Biol Med 153, 828–830 (2012). https://doi.org/10.1007/s10517-012-1836-z

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  • DOI: https://doi.org/10.1007/s10517-012-1836-z

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