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Correction of Endothelial Dysfunction in Patients with Arterial Hypertension

  • General Pathology and Pathological Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

We examined 38 patients (mean age 55.92 ± 1.56 years) with a 3-5-year history of arterial hypertension. The study showed that hypertension is accompanied by endothelial dysfunction and one of its forming factors is activation of the inflammatory response. Highly sensitive diagnostic tests can verify initiation of inflammation in preclinical manifestations. The use of nonsteroidal anti-inflammatory drugs, irrespective of the tropism to cyclooxygenase forms, alleviates manifestations of endothelial dysfunction in patients with arterial hypertension.

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Authors and Affiliations

  1. Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia

    M. A. Soloviev, N. V. Kulakova, T. A. Semiglazova, E. V. Borodulina & V. V. Udut

Authors
  1. M. A. Soloviev
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  2. N. V. Kulakova
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  3. T. A. Semiglazova
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  4. E. V. Borodulina
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  5. V. V. Udut
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Correspondence to V. V. Udut.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 151, No. 2, pp. 145–147, February, 2011

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Soloviev, M.A., Kulakova, N.V., Semiglazova, T.A. et al. Correction of Endothelial Dysfunction in Patients with Arterial Hypertension. Bull Exp Biol Med 151, 183–185 (2011). https://doi.org/10.1007/s10517-011-1284-1

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  • DOI: https://doi.org/10.1007/s10517-011-1284-1

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