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Free radical lipid peroxidation during amiodarone therapy for postinfarction cardiosclerosis

  • General Pathology and Pathophysiology
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Bulletin of Experimental Biology and Medicine Aims and scope

Postinfarction remodeling of the heart in animals with myocardial infarction was accompanied by activation of lipid peroxidation in myocardial tissue and blood serum and decrease in antioxidant enzyme activity. In animals with postinfarction cardiosclerosis treated with amiodarone, we observed decreased accumulation of lipid peroxidation products and normalization of superoxide dismutase activity.

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Authors and Affiliations

  1. Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia

    T. Yu. Rebrova & S. A. Afanasyev

Authors
  1. T. Yu. Rebrova
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  2. S. A. Afanasyev
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Correspondence to T. Yu. Rebrova.

Additional information

Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 146, No. 9, pp. 254–256, September, 2008

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Rebrova, T.Y., Afanasyev, S.A. Free radical lipid peroxidation during amiodarone therapy for postinfarction cardiosclerosis. Bull Exp Biol Med 146, 283–285 (2008). https://doi.org/10.1007/s10517-008-0281-5

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  • DOI: https://doi.org/10.1007/s10517-008-0281-5

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