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Effect of liposomal tetracycline hydrochloride on enzymatic function of the liver

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Abstract

Preparation and physicochemical properties of liposome-incorporated tetracycline are described. Comparison of the effects of tetracycline hydrochloride in free and liposome-incorporated forms on enzymatic functions of the liver showed that immobilization of the antibiotic into liposomes protects liver cells from functional disturbances.

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Authors and Affiliations

  1. Volgograd Research Antiplague Institute, Federal Service for Surveillance of Consumer Rights Protection and Human Well being, Volgograd, Russia

    S. N. Tikhonov, K. A. Rotov, N. P. Khrapova, V. V. Alekseev, E. A. Snatenkov, A. A. Zamarin & N. A. Simakova

Authors
  1. S. N. Tikhonov
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  2. K. A. Rotov
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  3. N. P. Khrapova
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  4. V. V. Alekseev
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  5. E. A. Snatenkov
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  6. A. A. Zamarin
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  7. N. A. Simakova
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Correspondence to S. N. Tikhonov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 4, pp. 421–423, April, 2008

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Tikhonov, S.N., Rotov, K.A., Khrapova, N.P. et al. Effect of liposomal tetracycline hydrochloride on enzymatic function of the liver. Bull Exp Biol Med 145, 443–445 (2008). https://doi.org/10.1007/s10517-008-0113-7

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  • DOI: https://doi.org/10.1007/s10517-008-0113-7

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