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Effect of β-adrenoblockers on heart rate variability in awake and narcotized rats

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Abstract

In narcotized rats, β-adrenoceptor blockers changed all parameters of heart rate variability indicating up-regulation of parasympathetic activity and down-regulation of the sympathetic one. In immobilized awake rats, the temporal and geometrical parameters varied similarly, while spectral analysis indicated possible activation of other neurohumoral mechanisms against the background of β-blocker treatment.

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Correspondence to M. M. Fateev.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 10, pp. 372–264, October, 2007

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Sal’nikov, E.V., Fateev, M.M., Sidorov, A.V. et al. Effect of β-adrenoblockers on heart rate variability in awake and narcotized rats. Bull Exp Biol Med 144, 494–497 (2007). https://doi.org/10.1007/s10517-007-0359-5

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  • DOI: https://doi.org/10.1007/s10517-007-0359-5

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