Abstract
Experiments on female (CBA×C57Bl/6)F1 mice with simultaneously transplanted Ehrlich carcinoma and B16 melanoma showed that removal of one of the primary nodes led to metastasizing of the removed tumor alone. It seems that this specificity of the inhibitory effect of the primary tumor can be explained by peculiarities of glycosylation and subsequent complex formation of serum proteins with the tumor.
Similar content being viewed by others
References
F. V. Donenko, S. M. Sitdikova, A. O. Kabieva, and L. V. Moroz, Byull. Eksp. Biol. Med., 114, No. 12, 652–654 (1992).
F. V. Donenko, S. M. Sitdikova, and L. V. Moroz, Ibid., 124, No. 10, 443–445 (1997).
S. M. Sitdikova, B. S. Amandzholov, V. Yu. Sel’chuk, and F. V. Donenko, Ibid., 135, No. 6, 676–679 (2003).
S. M. Sitdikova, B. S. Amandzholov, M. V. Serebryakova, et al., Ibid. , 141, No. 5, 563–566 (2006).
F. V. Donenko, S. M. Sitdikova, B. S. Amandzholov, and M. V. Kiselevskii, Ibid., 142, No. 9, 319–322 (2006).
C. J. Bruns, W. Liu, D. W. Davis, et al., Cancer, 89, No. 3, 488–499 (2000).
B. Fisher, N. Gunduz, J. Coyle, et al., Cancer Res., 49, No. 8, 1996–2001 (1989).
S. Fujita, T. Akasu, and Y. Moriya, Jpn. J. Clin. Oncol., 30, No. 1, 7–11 (2000).
C. F. Peeters, R. M. de Waal, T. Wobbes, et al., Int. J. Cancer, 119, No. 6, 1249–1253 (2006).
C. F. Peeters, J. R. Westphal, R. M. de Waal, et al., Ibid., 112, No. 4, 554–559 (2004).
Author information
Authors and Affiliations
Additional information
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 1, pp. 86–88, January, 2007
Rights and permissions
About this article
Cite this article
Sitdikova, S.M., Amandzholov, B.S., Kiselevskii, M.V. et al. Specificity of relapses and metastases of experimental transplanted Ehrlich carcinoma and B16 melanoma. Bull Exp Biol Med 143, 80–82 (2007). https://doi.org/10.1007/s10517-007-0022-1
Received:
Issue Date:
DOI: https://doi.org/10.1007/s10517-007-0022-1