Abstract
Full-thickness skin wounds (460 mm2) in rats were associated with increased blood chemiluminescence and neutrophil infiltration of the wound tissue and surrounding skin (recorded by myeloperoxidase activity). Activities of glutathione peroxidase and glutathione S-transferase in the skin and wound tissue increased on days 4 and 8. A correlation was revealed between activities of these enzymes and myeloperoxidase activity. Activities of myeloperoxidase and catalase increased in patient’s skin excised during plastic surgeries of more than 2.5 h duration.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 12, pp. 622–625, December, 2006
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Mikhal’chik, E.V., Anurov, M.V., Titkova, S.M. et al. Activity of antioxidant enzymes in the skin during surgical wounds. Bull Exp Biol Med 142, 667–669 (2006). https://doi.org/10.1007/s10517-006-0446-z
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DOI: https://doi.org/10.1007/s10517-006-0446-z