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Effect of photodynamic therapy with photodithazine on morphofunctional parameters of M-1 sarcoma

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Abstract

Efficiency and mechanisms of action of photodynamic therapy of M-1 sarcoma were studied experimentally on rats using photodithazine, a novel chlorine photosensitizer. The tissue and cellular targets for this agent are vascular wall, plasma membrane of tumor cells, and intracellular structures responsible for proliferation and biosynthesis.

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Correspondence to Yu. S. Romanko.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 12, pp. 658–664, December, 2004

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Romanko, Y.S., Tsyb, A.F., Kaplan, M.A. et al. Effect of photodynamic therapy with photodithazine on morphofunctional parameters of M-1 sarcoma. Bull Exp Biol Med 138, 584–589 (2004). https://doi.org/10.1007/s10517-005-0133-5

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  • DOI: https://doi.org/10.1007/s10517-005-0133-5

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