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Effects on lipid metabolism and expression of PPARα and FABP of Schizothorax prenanti by oxidized Konjac glucomannan

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Abstract

Prenant’s schizothoracin (Schizothorax prenanti) is an important existemic commercial fish in Yangtze River. Oxidized Konjac glucomannan (OKGM) is a kind of polysaccharide oxidative produced by degradation of KGM. A total of 500, 1000, 2000, 4000, and 8000 mg/kg OKGM were separately added to diets of S. prenanti. After 60 days of feeding trial, examinations were performed to determine activities of hepatic lipase (HL) lipoprotein lipase (LPL), contents of triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL) in serum, relative expressions of peroxisome proliferator activated receptor-α (PPARα) and fatty-acid-binding proteins (FABPs) of in muscle and hepatopancreas, lipids in fish meat, and fatty acids in lipids. Results showed that addition of 8000 mg/kg OKGM to diets of S. prenanti resulted in significantly higher activities of HL and LPL; significantly lower contents of TG, TC, and LDL; and significantly higher amounts of HDL (P < 0.05). Relative expressions of PPARα were significantly higher in hepatopancreas and back muscle. Fish meat contained significantly lower lipid contents, significantly higher levels of unsaturated fatty acids, and significantly lower amounts of saturated fatty acids (P < 0.05). Total contents of eicosapentaenoic acid, docosahexaenoic acid, and linolenic acid were significantly higher (P < 0.05). Lipids in muscles were significantly less than those of the control group (P < 0.05). Therefore, addition of OKGM to diets of S. prenanti affected lipid metabolism, and a significant effect was attained when the dose reached 8000 mg/kg.

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Acknowledgements

This research was financially supported by the Sichuan Province Science and Technology support projects of China (2009NZ0077-007) and Higher Education Department of Henan Province key scientific research projects (15A240008). The authors thank Professors Qiongzhi Li and Anxiang Wen for their help in acquiring test instruments.

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Authors and Affiliations

  1. Institute of Animal Nutrition and Genetics, Shangqiu Normal University, Shangqiu, 476000, Henan, People’s Republic of China

    Liao Zhang & Yongfeng Yan

  2. College of Food Science, Sichuan Agricultural University, Ya’an, 625014, Sichuan, People’s Republic of China

    Liao Zhang & Yinglong Wu

  3. Institute of Animal Nutrition, Sichuan Agricultural University, Ya’an, 625014, Sichuan, People’s Republic of China

    Liao Zhang & Yinglong Wu

  4. College of Art, Henan Normal University, Xinxiang, 453000, Henan, People’s Republic of China

    Ping Si

  5. College of Journalism and Communication, Shangqiu Normal University, Shangqiu, 476000, Henan, People’s Republic of China

    Ping Si

  6. Department of wild animal protection, Sichuan Agricultural University, Ya’an, 625014, Sichuan, People’s Republic of China

    Huailiang Xu & Yongfang Yao

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  1. Liao Zhang
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Zhang, L., Wu, Y., Si, P. et al. Effects on lipid metabolism and expression of PPARα and FABP of Schizothorax prenanti by oxidized Konjac glucomannan. Aquacult Int 25, 2007–2025 (2017). https://doi.org/10.1007/s10499-017-0168-4

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