Abstract
Adolescents with depression are at risk for negative long-term consequences and recurrence of depression. Many do not receive nor access treatment, especially Latino youth. New treatment approaches are needed. This study examined the feasibility and acceptability of a stepped collaborative care treatment model (SCIPT-A) for adolescents with depression utilizing interpersonal psychotherapy for adolescents (IPT-A) and antidepressant medication (if needed) compared to Enhanced Treatment as Usual (E-TAU) in urban pediatric primary care clinics serving primarily Latino youth. Results suggest the SCIPT-A model is feasible, acceptable and potentially beneficial for urban Latino adolescents. Clinicians delivered the SCIPT-A model with fidelity using supervision successfully implemented in a community setting.
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Alegria, M., Vallas, M., & Pumariega, A. J. (2010). Racial and ethnic disparities in pediatric mental health. Child and Adolescent Psychiatric Clinics of North America, 19(4), 759–774. https://doi.org/10.1016/j.chc.2010.07.001.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders. (4th edn., text rev.). Washington, DC: American Psychiatric Association.
Angstman, K. B., Phelan, S., Myszkowski, M. R., Schak, K. M., DeJesus, R. S., Lineberry, T. W., & van Ryn, M. (2015). Minority primary care patients with depression: Outcome disparities improve with collaborative care management. Medical Care, 53(1), 32–37. https://doi.org/10.1097/MLR.0000000000000280.
Asarnow, J. R., Jaycox, L. H., Duan, N., LaBorde, A. P., Rea, M. M., Murray, P., … Wells, K. B. (2005). Effectiveness of a quality improvement intervention for adolescent depression in primary care clinics: A randomized controlled trial. JAMA: The Journal of the American Medical Association, 293(3), 311–319.
Asarnow, J. R., Rozenman, M., Wiblin, J., & Zeltzer, L. (2015). Integrated medical-behavioral care compared with usual primary care for child and adolescent behavioral health: A meta-analysis. JAMA Pediatrics, 169(10), 929–937. https://doi.org/10.1001/jamapediatrics.2015.1141.
Bear, L., Finer, R., Guo, S., & Lau, A. S. (2014). Building the gateway to success: An appraisal of progress in reaching underserved families and reducing racial disparities in school-based mental health. Psychological Services, 11(4), 388–397. https://doi.org/10.1037/a0037969.
Birmaher, B., Brent, D., AACAP Work Group on Quality Issues, Bernet, W., Bulkstein, O., Walter, H., … Medicus, J. (2007). Practice parameter for the assessment and treatment of children and adolescents with depressive disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 46(11), 1503–1526.
Bower, P., & Gilbody, S. (2005). Stepped care in psychological therapies: Access, effectiveness and efficiency. Narrative literature review. The British Journal of Psychiatry, 186, 11–17.
Brown, J. D., Wissow, L. S., Zachary, C., & Cook, B. L. (2007). Receiving advice about child mental health from a primary care provider: African American and Hispanic parent attitudes. Medical Care, 45(11), 1076–1082. https://doi.org/10.1097/MLR.0b013e31812da7fd.
Campo, J. V., Shafer, S., Strohm, J., Lucas, A., Cassesse, C. G., Shaeffer, D., & Altman, H. (2005). Pediatric behavioral health in primary care: A collaborative approach. Journal of the American Psychiatric Nurses Association, 11(5), 276–282. https://doi.org/10.1177/1078390305282404.
Cauce, A. M., Domenech-Rodríguez, M., Paradise, M., Cochran, B. N., Shea, J. M., Srebnik, D., & Baydar, N. (2002). Cultural and contextual influences in mental health help seeking: A focus on ethnic minority youth. Journal of Consulting and Clinical Psychology, 70(1), 44–55.
Clarke, G., Debar, L., Lynch, F., Powell, J., Gale, J., O’Connor, E., … Hertert, S. (2005). A randomized effectiveness trial of brief cognitive-behavioral therapy for depressed adolescents receiving antidepressant medication. Journal of the American Academy of Child and Adolescent Psychiatry, 44(9), 888–898.
Cooper, L. A., Gonzales, J. J., Gallo, J. J., Rost, K. M., Meredith, L. S., Rubenstein, L. V., … Ford, D. E. (2003). The acceptability of treatment for depression among African-American, Hispanic, and white primary care patients. Medical Care, 41(4), 479–489.
David-Ferdon, C., & Kaslow, N. J. (2008). Evidence-based psychosocial treatments for child and adolescent depression. Journal of Clinical Child & Adolescent Psychology, 37(1), 62–104. https://doi.org/10.1080/15374410701817865.
Davis, T. D., Deen, T., Bryant-Bedell, K., Tate, V., & Fortney, J. (2011). Does minority racial-ethnic status moderate outcomes of collaborative care for depression? Psychiatric Services, 62(11), 1282–1288. https://doi.org/10.1176/ps.62.11.pss6211_1282.
Dwight-Johnson, M., Ell, K., & Lee, P. J. (2005). Can collaborative care address the needs of low-income Latinas with comorbid depression and cancer? Results from a randomized pilot study. Psychosomatics, 46(3), 224–232.
Emslie, G. J., Heiligenstein, J. H., Wagner, K. D., Hoog, S. L., Ernest, D. E., Brown, E., … Jacobson, J. G. (2002). Fluoxetine for acute treatment of depression in children and adolescents: A placebo-controlled, randomized clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 41(10), 1205–1215.
Emslie, G. J., Rush, A. J., Weinberg, W. A., Kowatch, R. A., Hughes, C. W., Carmody, T., & Rintelmann, J. (1997). A double-blind, randomized, placebo-controlled trial of fluoxetine in children and adolescents with depression. Archives of General Psychiatry, 54(11), 1031–1037.
Emslie, G. J., Ventura, D., Korotzer, A., & Tourkodimitris, S. (2009). Escitalopram in the treatment of adolescent depression: A randomized placebo-controlled multisite trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48(7), 721–729. https://doi.org/10.1097/CHI.0b013e3181a2b304.
Garcia, C. M., & Duckett, L. J. (2009). No te entiendo y tú no me entiendes: Language barriers among immigrant Latino adolescents seeking health care. Journal of Cultural Diversity, 16(3), 120–126.
Gilbody, S., Bower, P., Fletcher, J., Richards, D., & Sutton, A. J. (2006). Collaborative care for depression: A cumulative meta-analysis and review of longer-term outcomes. Archives of Internal Medicine, 166(21), 2314–2321.
Gilmer, T. P., Walker, C., Johnson, E. D., Philis-Tsimikas, A., & Unützer, J. (2008). Improving treatment of depression among Latinos with diabetes using Project Dulce and IMPACT. Diabetes care, 31(7), 1324–1326. https://doi.org/10.2337/dc08-0307.
Guo, S., Kataoka, S. H., Bear, L., & Lau, A. S. (2014). Differences in school-based referrals for mental health care: Understanding racial/ethnic disparities between Asian American and Latino youth. School Mental Health, 6(1), 27–39.
Guy, W. (1976). ECDEU assessment manual for psychopharmacology-revised. Rockville: U.S. Dept. of Health, Education, and Welfare Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute of Mental Health, Psychopharmacology Research Branch, Division of Extramural Research Programs.
Heneghan, A., Garner, A. S., Storfer-Isser, A., Kortepeter, K., Stein, R. E., & McCue Horwitz, S. (2008). Use of selective serotonin reuptake inhibitors by pediatricians: Comparing attitudes of primary care pediatricians and child adolescent psychiatrists. Clinical Pediatrics, 47(2), 148–154.
Hough, R. L., Hazen, A. L., Soriano, F. I., Wood, P., McCabe, K., & Yeh, M. (2002). Mental health care for Latinos: Mental health services for Latino adolescents with psychiatric disorders. Psychiatric Services, 53(12), 1556–1562. https://doi.org/10.1176/appi.ps.53.12.1556.
Ishikawa, R. Z., Cardemil, E. V., Alegría, M., Schuman, C. C., Joseph, R. C., & Bauer, A. M. (2014). Uptake of depression treatment recommendations among Latino primary care patients. Psychological Services, 11(4), 421–432. https://doi.org/10.1037/a0035716.
Jacobson, N. S., & Truax, P. (1991). Clinical significance: a statistical approach to defining to defining meaningful change in psychotherapy research. Journal of Consulting and Clinical Psychology, 59(1), 12–19.
Jonsson, U., Bohman, H., von Knorring, L., Olsson, G., Paaren, A., & von Knorring, A. L. (2011). Mental health outcome of long-term and episodic adolescent depression: 15-year follow-up of a community sample. Journal of Affective Disorders, 130(3), 395–404. https://doi.org/10.1016/j.jad.2010.10.046.
Katon, W. J. (2003). The institute of medicine “Chasm” report: Implications for depression collaborative care models. General Hospital Psychiatry, 25(4), 222–229.
Katon, W. J., Unützer, J., Wells, K., & Jones, L. (2010). Collaborative depression care: History, evolution and ways to enhance dissemination and sustainability. General Hospital Psychiatry, 32(5), 456–464. https://doi.org/10.1016/j.genhosppsych.2010.04.001.
Katon, W. J., Von Korff, M., Lin, E., & Simon, G. (2001). Rethinking practitioner roles in chronic illness: The specialist, primary care physician, and the practice nurse. General Hospital Psychiatry, 23(3), 138–144.
Kelleher, K. J., & Stevens, J. (2009). Evolution of child mental health services in primary care. Academic Pediatrics 9(1), 7–14. https://doi.org/10.1016/j.acap.2008.11.008.
Kim, R. E., Becker, K. D., Stephan, S. H., Hakimian, S., Apocada, D., Escudero, P. V., & Chorpita, B. F. (2015). Connecting students to mental health care: Pilot findings from an engagement program for school nurses. Advances in School Mental Health Promotion, 8(2), 87–103.
Kroenke, K., Spitzer, R. L., & Williams, J. B. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606–613.
Larsen, D. L., Attkisson, C. C., Hargreaves, W. A., & Nguyen, T. D. (1979). Assessment of client/patient satisfaction: Development of a general scale. Evaluation and Program Planning, 2(3), 197–207.
Luxton, D. D., June, J. D., & Comtois, K. A. (2013). Can postdischarge follow-up contacts prevent suicide and suicidal behavior? A review of the evidence. Crisis, 34(1), 32–41. https://doi.org/10.1027/0227-5910/a000158.
Merikangas, K. R., He, J.-P., Burstein, M., Swanson, S. A., Avenevoli, S., Cui, L., … Swendsen, J. (2010). Lifetime prevalence of mental disorders in U.S. adolescents: Results from the National Comorbidity Survey Replication-Adolescent Supplement (NCS-A). Journal of American Academy of Child and Adolescent Psychiatry, 49(10), 980–989. https://doi.org/10.1016/j.jaac.2010.05.017.
Merikangas, K. R., He, J.-P., Burstein, M., Swendsen, J., Avenevoli, S., Case, B., … Olfson, M. (2011). Service utilization for lifetime mental disorders in U.S. adolescents: Results of the National Comorbidity Survey-Adolescent Supplement (NCS-A). Journal of American Academy of Child and Adolescent Psychiatry, 50(1), 32–45. https://doi.org/10.1016/j.jaac.2010.10.006.
Mufson, L. (2010). Interpersonal psychotherapy for depressed adolescents (IPT-A): Extending the reach from academic to community settings. Child and Adolescent Mental Health, 15(2), 66–72. https://doi.org/10.1111/j.1475-3588.2009.00556.x.
Mufson, L., Clougherty, K., Young, J., Verdeli, H., & Yanes-Lukin, P. (2011). IPT-A consultation checklist—SCIPT-A adaptation. New York: State Psychiatric Institute, Columbia University College of Physicians and Surgeons.
Mufson, L., Dorta, K. P., Moreau, D., & Weissman, M. M. (2004a). Interpersonal psychotherapy for depressed adolescents (2nd edn.). New York: Guilford.
Mufson, L., Dorta, K. P., Wickramaratne, P., Nomura, Y., Olfson, M., & Weissman, M. M. (2004b). A randomized effectiveness trial of interpersonal psychotherapy for depressed adolescents. Archives of General Psychiatry, 61(6), 577–584.
Mufson, L., Weissman, M. M., Moreau, D., & Garfinkel, R. (1999). Efficacy of interpersonal psychotherapy for depressed adolescents. Archives of General Psychiatry, 56(6), 573–579.
Mufson, L., Yanes-Lukin, P., & Anderson, G. (2015). A pilot study of Brief IPT-A delivered in primary care. General Hospital Psychiatry, 37(5), 481–484. https://doi.org/10.1016/j.genhosppsych.2015.04.013.
Mufson, L., Yanes-Lukin, P., Gunlicks-Stoessel, M., & Wickramaratne, P. (2014). Cultural competency and its effect on treatment outcome of IPT-A in school-based health clinics. American Journal of Psychotherapy, 68(4), 417–442.
National Institute for Health and Care Excellence. (2009). Depression in adults: Recognition and management (NICE Quality Standard No. 90). Retrieved from https://www.nice.org/guidance/cg90.
Potochnick, S. R., & Perreira, K. M. (2010). Depression and anxiety among first-generationimmigrant Latino youth: Key correlates and implications for future research. The Journal of Nervous and Mental Disease, 198(7), 470–477. https://doi.org/10.1097/NMD.0b013e3181e4ce24.
Poznanski, E. O., Grossman, J. A., Buchsbaum, Y., Banegas, M., Freeman, L., & Gibbons, R. (1984). Preliminary studies of the reliability and validity of the children’s depression rating scale. Journal of the American Academy of Child and Adolescent Psychiatry, 23(2), 191–197.
Poznanski, E. O., & Mokros, H. B. (1996). Children’s Depression Rating Scale-Revised (CDRS-R). Los Angeles: WPS.
Proctor, E., Silmere, H., Raghavan, R., Hovmand, P., Aarons, G., Bunger, A., … Hensley, M. (2011). Outcomes for implementation research: Conceptual distinctions, measurement challenges, and research agenda. Administration and Policy in Mental Health, 38(2), 65–76. https://doi.org/10.1007/s10488-010-0319-7.
Richards, D. A., Lovell, K., Gilbody, S., Gask, L., Torgerson, D., Barkham, M., … Richardson, R. (2008). Collaborative care for depression in UK primary care: A randomized controlled trial. Psychological Medicine, 38(2), 279–287.
Richardson, L. P., Ludman, E., McCauley, E., Lindenbaum, J., Larison, C., Zhou, C., … Katon, W. (2014). Collaborative care for adolescents with depression in primary care: A randomized clinical trial. JAMA, 312(8), 809–816. https://doi.org/10.1001/jama.2014.9259.
Richardson, L. P., McCauley, E., Grossman, D. C., McCarty, C. A., Richards, J., Russo, J. E., … Katon, W. (2010). Evaluation of the Patient Health Questionnaire (PHQ-9) for detecting major depression among adolescents. Pediatrics, 126(6), 1117–1123. https://doi.org/10.1542/peds.2010-0852.
Richardson, L. P., McCauley, E., & Katon, W. (2009). Collaborative care for adolescent depression: A pilot study. General Hospital Psychiatry, 31(1), 36–45. https://doi.org/10.1016/j.genhosppsych.2008.09.019.
Rosselló, J., & Bernal, G. (1999). The efficacy of cognitive-behavioral and interpersonal treatments for depression in Puerto Rican adolescents. Journal of Consulting and Clinical Psychology, 67(5), 734–745.
Rosselló, J., Bernal, G., & Rivera-Medina, C. (2008). Individual and group CBT and IPT for Puerto Rican adolescents with depressive symptoms. Cultural Diversity & Ethnic Minority Psychology, 14(3), 234–245. https://doi.org/10.1037/1099-9809.14.3.234.
Rushton, J., Bruckman, D., & Kelleher, K. (2002). Primary care referral of children with psychosocial problems. Archives of Pediatrics & Adolescent Medicine, 156(6), 592–598.
Sayal, K. (2006). Annotation: Pathways to care for children with mental health problems. Journal of Child Psychology and Psychiatry, 47(7), 649–659.
Shaffer, D., Fisher, F., Lucas, C. P., Dulcan, M. K., & Schwab-Stone, M. E. (2000). CDS (Columbia Depression scale).
Shaffer, D., Gould, M. S., Brasic, J., Ambrosini, P., Fisher, P., Bird, H., & Aluwahlia, S. (1983). A children’s global assessment scale (CGAS). Archives of General Psychiatry, 40(11), 1228–1231.
Thapar, A., Collishaw, S., Pine, D. S., & Thapar, A. K. (2012). Depression in adolescence. Lancet, 379(9820), 1056–1067. https://doi.org/10.1016/S0140-6736(11)60871-4.
Thota, A. B., Sipe, T. A., Byard, G. J., Zometa, C. S., Hahn, R. A., McKnight-Eily, L. R. … Community Preventive Services Task Force. (2012). Collaborative care to improve the management of depressive disorders: A community guide systematic review and meta-analysis. American Journal of Preventive Medicine, 42(5), 525–538. https://doi.org/10.1016/j.amepre.2012.01.019.
US Preventive Task Force. (2009). Screening and treatment for major depressive disorder in children and adolescents: US Preventive Services Task Force recommendation statement. Pediatrics, 123(4), 1223–1228. https://doi.org/10.1542/peds.2008-2381.
Van Voorhees, B. W., Fogel, J., Reinecke, M. A., Gladstone, T., Stuart, S., Gollan, J., … Bell, C. (2009). Randomized clinical trial of an internet-based depression prevention program for adolescents (Project CATCH-IT) in primary care: 12 week outcomes. Journal of Developmental and Behavioral Pediatrics, 30(1), 23–37. https://doi.org/10.1097/DBP.0b013e3181966c2a.
van’t Veer-Tazelaar, P. J., van Marwijk, H. W., van Oppen, P., van Hout, H. P., van der Horst, H. E., Cuijpers, P., … Beekman, A. T. (2009). Stepped-care prevention of anxiety and depression in late life: A randomized controlled trial. Archives of General Psychiatry, 66(3), 297–304. https://doi.org/10.1001/archgenpsychiatry.2008.555.
Wagner, K. D., Jonas, J., Findling, R. L., Ventura, D., & Saikali, K. (2006). A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression. Journal of the American Academy of Child and Adolescent Psychiatry, 45(3), 280–288.
Weersing, V. R., Brent, D. A., Rozenman, M. S., Gonzalez, A., Jeffreys, M., Dickerson, J. F., … Iyengar, S. (2017). Brief behavioral therapy for pediatric anxiety and depression in primary care: A randomized clinical trial. JAMA Psychiatry, 74(6), 571–578. https://doi.org/10.1001/jamapsychiatry.2017.0429.
Weersing, V. R., Gonzalez, A., Campo, J. V., & Lucas, A. N. (2008). Brief behavioral therapy for pediatric anxiety and depression: Piloting an integrated treatment approach. Cognitive and Behavioral Practice, 15(2), 126–139. https://doi.org/10.1016/j.cbpra.2007.10.001.
Weissman, M. M., & Bothwell, S. (1976). Assessment of social adjustment by patient self-report. Archives of General Psychiatry, 33(9), 1111–1115.
Williams, D. R., González, H. M., Neighbors, H., Nesse, R., Abelson, J. M., Sweetman, J., & Jackson, J. S. (2007). Prevalence and distribution of major depressive disorder in African Americans, Caribbean blacks, and non-Hispanic whites: Results from the National Survey of American Life. Archives of General Psychiatry, 64(3), 305–315.
Yeh, M., McCabe, K., Hough, R. L., Dupuis, D., & Hazen, A. (2003). Racial/ethnic differences in parental endorsement of barriers to mental health services for youth. Mental Health Services Research, 5(2), 65–77.
Acknowledgements
We would like to thank the pediatricians, social workers, and staff at the NewYork Presbyterian Hospital Ambulatory Pediatric Clinics for their commitment to making this study a success, Drs. Roberto Lewis-Fernández and Mark Olfson (from the Department of Psychiatry, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, NY, USA) for their valuable insights in designing and executing the study as well as their feedback on the manuscript, and our clinical evaluators and volunteer staff who also contributed to the successful completion of the project.
Funding
This study was funded by the National Institute of Mental Health Grant # R34 MH091320.
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Mufson receives book royalties from Guilford Press, Inc. and Oxford University Press, and has received speaker honorarium from Janssen Pharmaceuticals and research support from the National Institute of Mental Health. She has received fees for academic lectures and Ground Rounds. Rynn has received research support from the National Institute of Mental Health (NIMH), the National Institute of Child Health and Human Development (NICHD), Eli Lilly and Shire. She has served as a consultant to Shire and has received royalties from American Psychiatric Publishing and a writing fee from Oxford University Press. She has received fees for academic lectures and Ground Rounds. The other authors declare that they have no conflict of interest.
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All authors complied with APA ethical standards in the treatment of participants and all work was approved by the Institutional Review Board at the New York State Psychiatric Institute. Informed consent/assent was obtained from all study participants and their parents, if applicable.
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Mufson, L., Rynn, M., Yanes-Lukin, P. et al. Stepped Care Interpersonal Psychotherapy Treatment for Depressed Adolescents: A Pilot Study in Pediatric Clinics. Adm Policy Ment Health 45, 417–431 (2018). https://doi.org/10.1007/s10488-017-0836-8
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DOI: https://doi.org/10.1007/s10488-017-0836-8