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Survival mechanisms and culturability of Campylobacter jejuni under stress conditions

  • Review Paper
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Abstract

Culture-based isolation and enumeration of bacterial human pathogens from environmental and human food samples has significant limitations. Many pathogens enter a viable but non-culturable (VBNC) state in response to stress, and cannot be detected via culturing methods. Favourable growth conditions with a source of energy and an ideal stoichiometric ratio of carbon to inorganic elements can reverse this VBNC state. This review will focus on the bacterium Campylobacter jejuni which is a leading cause of food borne illness in the developed world. C. jejuni can enter a VBNC state in response to extremes in: pH, moisture content, temperature, nutrient content and salinity. Once in a VBNC state, the organism must maintain an energy balance from substrate oxidation through respiration to grow, divide and remain viable. The goal of this review is a greater understanding of how abiotic stress and thermodynamics influence the viability of C. jejuni.

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Authors and Affiliations

  1. School of Environmental Sciences, University of Guelph, Guelph, ON, N1G 2Wl, Canada

    D. Nathan Jackson, Bailey Davis, Sandra M. Tirado, Megha Duggal, Jessica K. van Frankenhuyzen, Deanna Deaville, M. A. K. Wijesinghe & J. T. Trevors

  2. Department of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2Wl, Canada

    Michael Tessaro

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  1. D. Nathan Jackson
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  2. Bailey Davis
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  3. Sandra M. Tirado
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  4. Megha Duggal
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  5. Jessica K. van Frankenhuyzen
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  6. Deanna Deaville
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  7. M. A. K. Wijesinghe
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  8. Michael Tessaro
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  9. J. T. Trevors
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Correspondence to J. T. Trevors.

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Jackson, D.N., Davis, B., Tirado, S.M. et al. Survival mechanisms and culturability of Campylobacter jejuni under stress conditions. Antonie van Leeuwenhoek 96, 377–394 (2009). https://doi.org/10.1007/s10482-009-9378-8

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  • DOI: https://doi.org/10.1007/s10482-009-9378-8

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