Abstract
Since the introduction of antiretroviral therapy, the number of women living with HIV (WLHIV) continues to increase. Despite the decrease in HIV diagnosis among women in California, less than half of WLHIV are retained in HIV care. Structural barriers put women at increased risk for delayed HIV diagnosis, delayed entry into HIV care, and poorer treatment outcomes. The objective of this qualitative analysis is to identify how structural barriers negatively impact women’s sustained engagement in HIV care in Southern California. WLHIV accessing local HIV support services participated in a qualitative study by completing a semi-structured interview and brief survey between January and April 2015 (n = 30). Poverty, unemployment, housing instability, and needs for transportation emerged as the dominant structural barriers for women when discussing their challenges with sustained engagement in HIV care. System-level interventions that decrease these noted barriers may help improve HIV care continuum for women living in Southern California.
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References
Deeks SG, Lewin SR, Havlir DV. The end of AIDS: HIV infection as a chronic disease. Lancet. 2013;382(9903):1525–33.
Gardner EM, McLees MP, Steiner JF, del Rio C, Burman WJ. The Spectrum of engagement in HIV Care and its relevance to test-and-treat strategies for prevention of HIV Infection. Clin Infect Dis. 2011;52(6):793–800.
Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493–505.
Rodger AJ, Cambiano V, Bruun T, Vernazza P, Collins S, van Lunzen J, et al. Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy. JAMA. 2016;316(2):171–81.
Loutfy MR, Wu W, Letchumanan M, Bondy L, Antoniou T, Margolese S, et al. Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral therapy. PLoS ONE. 2013;8(2):e55747.
LeMessurier J, Traversy G, Varsaneux O, Weekes M, Avey MT, Niragira O, et al. Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: a systematic review. CMAJ. 2018;190(46):E1350–E13601360.
Adimora AA, Auerbach JD. Structural interventions for HIV prevention in the United States. J Acquir Immun Def. 2010;55:S132–S135135.
Wang EA, McGinnis KA, Fiellin DA, Goulet JL, Bryant K, Gibert CL, et al. Food insecurity is associated with poor virologic response among HIV-infected patients receiving antiretroviral medications. J Gen Intern Med. 2011;26(9):1012–8.
Young S, Wheeler A, McCoy S, Weiser SD. A review of the role of food insecurity in adherence to care and treatment among adult and pediatric populations living with HIV and AIDS. Aids Behav. 2014;18(5):505–15.
Weiser SD, Frongillo EA, Ragland K, Hogg RS, Riley ED, Bangsberg DR. Food insecurity is associated with incomplete HIV RNA suppression among homeless and marginally housed HIV-infected individuals in San Francisco. J Gen Intern Med. 2009;24(1):14–20.
Weiser SD, Bangsberg DR, Kegeles S, Ragland K, Kushel MB, Frongillo EA. Food insecurity among homeless and marginally housed individuals living with HIV/AIDS in San Francisco. Aids Behav. 2009;13(5):841–8.
Milloy MJ, Marshall BD, Montaner J, Wood E. Housing status and the health of people living with HIV/AIDS. Curr HIV/AIDS Rep. 2012;9(4):364–74.
Aidala AA, Wilson MG, Shubert V, Gogolishvili D, Globerman J, Rueda S, et al. Housing status, medical care, and health outcomes among people living with HIV/AIDS: a systematic review. Am J Public Health. 2016;106(1):e1–e23.
Kidder DP, Wolitski RJ, Royal S, Aidala A, Courtenay-Quirk C, Holtgrave DR, et al. Access to housing as a structural intervention for homeless and unstably housed people living with HIV: rationale, methods, and implementation of the housing and health study. Aids Behav. 2007;11(6 Suppl):149–61.
Leaver CA, Bargh G, Dunn JR, Hwang SW. The effects of housing status on health-related outcomes in people living with HIV: a systematic review of the literature. Aids Behav. 2007;11(6 Suppl):85–100.
Riley ED, Moore K, Sorensen JL, Tulsky JP, Bangsberg DR, Neilands TB. Basic subsistence needs and overall health among human immunodeficiency virus-infected homeless and unstably housed women. Am J Epidemiol. 2011;174(5):515–22.
Institute of Medicine. Monitoring HIV care in the United States: indicators and data systems. Washington, DC; 2012.
Kennedy MC, Kerr T, McNeil R, Parashar S, Montaner J, Wood E, et al. Residential eviction and risk of detectable plasma HIV-1 RNA viral load among HIV-positive people who use drugs. Aids Behav. 2017;21(3):678–87.
Clemenzi-Allen A, Geng E, Christopoulos K, Hammer H, Buchbinder S, Havlir D, et al. Degree of housing instability shows independent "dose-response" with virologic suppression rates among people living with human immunodeficiency virus. Open Forum Infect Dis. 2018;5(3):ofy035.
Riley ED, Vittinghoff E, Koss CA, Christopoulos KA, Clemenzi-Allen A, Dilworth SE, et al. Housing first: unsuppressed viral load among women living with HIV in San Francisco. Aids Behav. 2019;23(9):2326–36.
Sarnquist CC, Soni S, Hwang H, Topol BB, Mutima S, Maldonado YA. Rural HIV-infected women's access to medical care: ongoing needs in California. Aids Care. 2011;23(7):792–6.
California Department of Public Health, Office of AIDS. Epidemiology of HIV in California. 2017.
Fauci AS, Redfield RR, Sigounas G, Weahkee MD, Giroir BP. Ending the HIV epidemic: a plan for the United States. Jama; 2019.
Office of AIDS. California Continuum of HIV Care. In: Health CDoP, editor. CA; 2017.
The U.S. Department of Housing and Urban Development. The 2017 Annual Homeless Assessment Report to Congress. Office of Community Planning and Development; 2017.
Pellowski JA, Kalichman SC, Matthews KA, Adler N. A pandemic of the poor: social disadvantage and the U.S. HIV epidemic. Am Psychol. 2013;68(4):197–209.
Aziz M, Smith KY. Challenges and successes in linking HIV-infected women to care in the United States. Clin Infect Dis. 2011;52(suppl_2):S231–S237237.
Aziz M, Smith KY. Treating women with HIV: is it different than treating men? Curr HIV-AIDS Rep. 2012;9(2):171–8.
Gomez CA. Preventing HIV in U.S. women and girls: a call for social action. Women's Health Issues. 2011;21(6 Suppl):S287–S294294.
Centers for Disease Control and Prevention. HIV surveillance report. Atlanta, Georgia; 2017.
NOVA Research Company. QDS™: questionnaire development system 20. Silver Spring, MD; 2014
Morse JM, Denzin NK, Lincoln YS. Designing qualitative research; 1994.
Berry SH, Bozzette SA, Hays RD, Stewart A, Kanouse DE. Measuring patient-reported health status in advanced HIV disease: HIV-PARSE survey instrument. Santa Monica: RAND Corporation; 1994.
Creswell JW. Research design: qualitative, quantitative, and mixed methods approaches. 4th ed. Thousand Oaks: SAGE Publications; 2014. p. 273.
Gale NK, Heath G, Cameron E, Rashid S, Redwood S. Using the framework method for the analysis of qualitative data in multi-disciplinary health research. BMC Med Res Methodol. 2013;13:117.
Milloy MJ, Kerr T, Bangsberg DR, Buxton J, Parashar S, Guillemi S, et al. Homelessness as a structural barrier to effective antiretroviral therapy among HIV-seropositive illicit drug users in a Canadian setting. AIDS Patient Care STDS. 2012;26(1):60–7.
Riley ED, Gandhi M, Hare C, Cohen J, Hwang S. Poverty, unstable housing, and HIV infection among women living in the United States. Curr HIV/AIDS Rep. 2007;4(4):181–6.
Luck J, Andersen R, Wenzel S, Arangua L, Wood D, Gelberg L. Providers of primary care to homeless women in Los Angeles County. J Ambul Care Manage. 2002;25(2):53–67.
Gelberg L, Browner CH, Lejano E, Arangua L. Access to women's health care: a qualitative study of barriers perceived by homeless women. Women Health. 2004;40(2):87–100.
Berg KM, Demas PA, Howard AA, Schoenbaum EE, Gourevitch MN, Arnsten JH. Gender differences in factors associated with adherence to antiretroviral therapy. J Gen Intern Med. 2004;19(11):1111–7.
Palepu A, Milloy MJ, Kerr T, Zhang R, Wood E. Homelessness and adherence to antiretroviral therapy among a cohort of HIV-infected injection drug users. J Urban Health. 2011;88(3):545–55.
Cox J, Maurais E, Hu L, Moodie EE, Law S, Bozinoff N, et al. Correlates of drug use cessation among participants in the Canadian HIV-HCV co-infection cohort. Drug Alcohol Depend. 2014;137:121–8.
Krishnan A, Wickersham JA, Chitsaz E, Springer SA, Jordan AO, Zaller N, et al. Post-release substance abuse outcomes among HIV-infected jail detainees: results from a multisite study. Aids Behav. 2013;17(Suppl 2):S171–S180180.
Bobashev GV, Zule WA, Osilla KC, Kline TL, Wechsberg WM. Transactional sex among men and women in the south at high risk for HIV and other STIs. J Urban Health. 2009;86(Suppl 1):32–47.
Bailey SL, Camlin CS, Ennett ST. Substance use and risky sexual behavior among homeless and runaway youth. J Adolesc Health. 1998;23(6):378–88.
Meacham MC, Bahorik AL, Shumway M, Marquez C, Riley ED. Condomless sex and psychiatric comorbidity in the context of constrained survival choices: a longitudinal study among homeless and unstably housed women. Aids Behav. 2019;23(3):802–12.
Cederbaum JA, Wenzel SL, Gilbert ML, Chereji E. The HIV risk reduction needs of homeless women in Los Angeles. Women's Health Issues. 2013;23(3):e167–e172172.
Duke AR, Searby A. Mental ill health in homeless women: a review. Issues Ment Health Nurs. 2019;40:1–8.
California Department of Public Health. California needs assessment for HIV. Sacramento: Office of AIDS; 2016.
Moneyham L, McLeod J, Boehme A, Wright L, Mugavero M, Seal P, et al. Perceived barriers to HIV care among HIV-infected women in the deep south. J Assoc Nurse Aids C. 2010;21(6):467–77.
Vyavaharkar MV, Moneyham L, Corwin S. Health care utilization: the experiences of rural HIV-positive African American women. J Health Care Poor Underserved. 2008;19(1):294–306.
Kempf MC, McLeod J, Boehme AK, Walcott MW, Wright L, Seal P, et al. A qualitative study of the barriers and facilitators to retention-in-care among HIV-positive women in the rural southeastern United States: implications for targeted interventions. Aids Patient Care St. 2010;24(8):515–20.
Mandsager P, Marier A, Cohen S, Fanning M, Hauck H, Cheever LW. Reducing HIV-related health disparities in the health resources and services administration's Ryan white HIV/AIDS program. Am J Public Health. 2018;108(S4):S246–S250250.
Buchanan D, Kee R, Sadowski LS, Garcia D. The health impact of supportive housing for HIV-positive homeless patients: a randomized controlled trial. Am J Public Health. 2009;99(S3):S675–S680680.
Galarraga O, Genberg BL, Martin RA, Barton Laws M, Wilson IB. Conditional economic incentives to improve HIV treatment adherence: literature review and theoretical considerations. Aids Behav. 2013;17(7):2283–92.
Operario D, Kuo C, Sosa-Rubi SG, Galarraga O. Conditional economic incentives for reducing HIV risk behaviors: integration of psychology and behavioral economics. Health Psychol. 2013;32(9):932–40.
Acknowledgements
The authors acknowledge the clients and peer navigators of a local HIV service agency in San Diego, California for their participation to this research. JKS received partial support by award number UL1TR000100 from the National Center for Advancing Translational Sciences, and the Altman Clinical and Translational Research Institute Academic-Community Partnership Pilot Project Grant at the University of California, San Diego. LRS was supported by award number K01 DA039767 from the National Institute on Drug Abuse. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies.
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Park, E., Stockman, J.K., Thrift, B. et al. Structural Barriers to Women’s Sustained Engagement in HIV Care in Southern California. AIDS Behav 24, 2966–2974 (2020). https://doi.org/10.1007/s10461-020-02847-9
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DOI: https://doi.org/10.1007/s10461-020-02847-9