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Psychological Distress Among Methadone Maintenance Patients in Vietnamese Mountainous Areas

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Abstract

We conducted a cross-sectional study in Tuyen Quang Province, a mountainous province in northern Vietnam, to examine rates of psychological distress among 241 patients receiving methadone maintenance treatment (MMT). Using the Kessler psychological distress Scale, we found that approximately one-fourth (26.8%) of respondents suffered from mental health pathologies. Physical health problems, current drug use, and alcohol abuse were found to be associated with mental health problems among the participants. Our findings highlight the high prevalence of psychological distress among MMT patients in northern Vietnam, and the need to integrate mental and physical health care services, as well as behavioral health counseling, into currently existing MMT clinics in this region.

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References

  1. Ridner SH. Psychological distress: concept analysis. J Adv Nurs. 2004;45(5):536–45.

    Article  PubMed  Google Scholar 

  2. Lai HM, Cleary M, Sitharthan T, Hunt GE. Prevalence of comorbid substance use, anxiety and mood disorders in epidemiological surveys, 1990-2014: A systematic review and meta-analysis. Drug Alcohol Depend. 2015;154:1–13.

    Article  PubMed  Google Scholar 

  3. Chen VC, Lin TY, Lee CT, Lai TJ, Chen H, Ferri CP, et al. Suicide attempts prior to starting methadone maintenance treatment in Taiwan. Drug Alcohol Depend. 2010;109(1–3):139–43.

    Article  PubMed  Google Scholar 

  4. Darke S, Williamson A, Ross J, Teesson M, Lynskey M. Borderline personality disorder, antisocial personality disorder and risk-taking among heroin users: findings from the australian treatment outcome study (ATOS). Drug Alcohol Depend. 2004;74(1):77–83.

    Article  PubMed  Google Scholar 

  5. Huang CL, Lee CW. Factors associated with mortality among heroin users after seeking treatment with methadone: a population-based cohort study in Taiwan. J Subst Abuse Treat. 2013;44(3):295–300.

    Article  PubMed  Google Scholar 

  6. Carpentier PJ, Krabbe PF, van Gogh MT, Knapen LJ, Buitelaar JK, de Jong CA. Psychiatric comorbidity reduces quality of life in chronic methadone maintained patients. The Am J Addict. 2009;18(6):470–80.

    Article  PubMed  Google Scholar 

  7. Yen CN, Wang CS, Wang TY, Chen HF, Chang HC. Quality of life and its correlates among heroin users in Taiwan. Kaohsiung J Med Sci. 2011;27(5):177–83.

    Article  PubMed  Google Scholar 

  8. Fassino S, Daga GA, Delsedime N, Rogna L, Boggio S. Quality of life and personality disorders in heroin abusers. Drug Alcohol Depend. 2004;76(1):73–80.

    Article  CAS  PubMed  Google Scholar 

  9. Mulder RT, Frampton CM, Luty SE, Joyce PR. Eighteen months of drug treatment for depression: predicting relapse and recovery. J Affect Disord. 2009;114(1–3):263–70.

    Article  PubMed  Google Scholar 

  10. Hatsukami D, Pickens RW, Svikis D. Post-treatment depressive symptoms and relapse to drug use in different age groups of an alcohol and other drug abuse population. Drug Alcohol Depend. 1981;8(4):271–7.

    Article  CAS  PubMed  Google Scholar 

  11. Carreras Alabau A, Carrobles Isabel JA, Almendros Rodriguez C. Perceived stress related to methadone withdrawal. Psicothema. 2016;28(3):235–40.

    PubMed  Google Scholar 

  12. McGovern MP, Xie H, Segal SR, Siembab L, Drake RE. Addiction treatment services and co-occurring disorders: Prevalence estimates, treatment practices, and barriers. J Subst Abuse Treat. 2006;31(3):267–75.

    Article  PubMed  Google Scholar 

  13. Brooner RK, King VL, Kidorf M, Schmidt CW Jr, Bigelow GE. Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry. 1997;54(1):71–80.

    Article  CAS  PubMed  Google Scholar 

  14. Callaly T, Trauer T, Munro L, Whelan G. Prevalence of psychiatric disorder in a methadone maintenance population. The Australian and New Zealand journal of psychiatry. 2001;35(5):601–5.

    Article  CAS  PubMed  Google Scholar 

  15. Rosen D, Smith ML, Reynolds CF 3rd. The prevalence of mental and physical health disorders among older methadone patients. Am J Geriatr Psychiatry. 2008;16(6):488–97.

    Article  PubMed  Google Scholar 

  16. Brienza RS, Stein MD, Chen M, Gogineni A, Sobota M, Maksad J, et al. Depression among needle exchange program and methadone maintenance clients. J Subst Abuse Treat. 2000;18(4):331–7.

    Article  CAS  PubMed  Google Scholar 

  17. Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, et al. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry. 2004;61(8):807–16.

    Article  PubMed  Google Scholar 

  18. Mortazavi SS, Shati M, Malakouti SK, Mohammad K. Psychiatric comorbidities among Iranian elderly patients on methadone maintenance treatment. Arch Iran Med. 2015;18(11):740–6.

    PubMed  Google Scholar 

  19. Mason BJ, Kocsis JH, Melia D, Khuri ET, Sweeney J, Wells A, et al. Psychiatric comorbidity in methadone maintained patients. J Addict Dis. 1998;17(3):75–89.

    Article  CAS  PubMed  Google Scholar 

  20. Teoh Bing Fei J, Yee A, Habil MH. Psychiatric comorbidity among patients on methadone maintenance therapy and its influence on quality of life. Am J Addict. 2016;25(1):49–55.

    Article  PubMed  Google Scholar 

  21. Vietnam Go. Vietnam AIDS Response Progress Report 2012. Hanoi, Vietnam: National Committee for AIDS, Drugs and Prostitution Prevention and Control, 2012

  22. Control VAoHA. The annual review of HIV/AIDS control and prevention in the first six months 2016 and action plan in the last six months in 2016. Hanoi: 2016.

  23. Health VMo. Decision No 3140/QD-BYT on Guideline for Substance abuse treatment using methadone. Hanoi 2010.

  24. Vuong DA, Van Ginneken E, Morris J, Ha ST, Busse R. Mental health in Vietnam: Burden of disease and availability of services. Asian J Psychiatry. 2011;4(1):65–70.

    Article  Google Scholar 

  25. Tran BX, Ohinmaa A, Mills S. Multilevel predictors of concurrent opioid use during methadone maintenance treatment among drug users with HIV/AIDS. PLoS ONE. 2012;7:e51569.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Tran BX, Nguyen LH, Nguyen LP, Nguyen CT, Phan HTT, Latkin CA. Methadone maintenance treatment promotes referral and uptake of HIV testing and counselling services amongst drug users and their partners. PLoS ONE. 2016;11(4):e0152804.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Tran BX, Nguyen LH, Nong VM, Nguyen CT, Phan HT, Latkin CA. Behavioral and quality-of-life outcomes in different service models for methadone maintenance treatment in Vietnam. Harm Reduct J. 2016;13:4.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Decree No:96/2012/ND-CP on regulating Substitution Treatment of Opioid Addiction, (2012).

  29. Nguyen T, Dennis S, An H, Vagholkar S, Liaw ST. Psychological distress among Vietnamese adults attending Vietnamese-speaking general practices in South Western Sydney: prevalence and associations. Aust J Prim Health. 2015;22(4):354–9.

    Article  PubMed  Google Scholar 

  30. Andrews G, Slade T. Interpreting scores on the Kessler Psychological Distress Scale (K10). Aust N Z J Public Health. 2001;25(6):494–7.

    Article  CAS  PubMed  Google Scholar 

  31. Stolk Y, Kaplan I, Szwarc J. Clinical use of the Kessler psychological distress scales with culturally diverse groups. Int J Method Psychiatr Res. 2014;23(2):161–83.

    Article  Google Scholar 

  32. Tran BX, Nguyen LH, Nong VM, Nguyen CT. Health status and health service utilization in remote and mountainous areas in Vietnam. Health Quality Life Outcomes. 2016;14(1):85.

    Article  Google Scholar 

  33. Jane-Llopis E, Matytsina I. Mental health and alcohol, drugs and tobacco: a review of the comorbidity between mental disorders and the use of alcohol, tobacco and illicit drugs. Drug Alcohol Rev. 2006;25(6):515–36.

    Article  PubMed  Google Scholar 

  34. Ryder AG, Yang J, Zhu X, Yao S, Yi J, Heine SJ, et al. The cultural shaping of depression: somatic symptoms in China, psychological symptoms in North America? J Abnorm Psychol. 2008;117(2):300–13.

    Article  PubMed  Google Scholar 

  35. Steel Z, Silove D, Giao NM, Phan TTB, Chey T, Whelan A, et al. International and indigenous diagnoses of mental disorder among Vietnamese living in Vietnam and Australia. Br J Psychiatry. 2009;194(4):326–33.

    Article  PubMed  Google Scholar 

  36. Peles E, Schreiber S, Gordon J, Adelson M. Significantly higher methadone dose for methadone maintenance treatment (MMT) patients with chronic pain. Pain. 2005;113(3):340–6.

    Article  CAS  PubMed  Google Scholar 

  37. Group E. EQ-5D-5L User Guide: Basic information on how to use the EQ-5D-5L instrument Rotterdam, The Netherlands2011 [cited 2013 1-9]. Available from: http://www.euroqol.org/fileadmin/user_upload/Documenten/PDF/Folders_Flyers/UserGuide_EQ-5D-5L.pdf.

  38. Tran BX, Ohinmaa A, Nguyen LT. Quality of life profile and psychometric properties of the EQ-5D-5L in HIV/AIDS patients. Health Qual Life Outcomes. 2012;10:132.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Bradley KA, DeBenedetti AF, Volk RJ, Williams EC, Frank D, Kivlahan DR. AUDIT-C as a brief screen for alcohol misuse in primary care. Alcohol Clin Exp Res. 2007;31(7):1208–17.

    Article  PubMed  Google Scholar 

  40. Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V, et al. The global prevalence of common mental disorders: a systematic review and meta-analysis 1980–2013. Int J Epidemiol. 2014;19:dyu038.

    Google Scholar 

  41. Compton WM 3rd, Helzer JE, Hwu HG, Yeh EK, McEvoy L, Tipp JE, et al. New methods in cross-cultural psychiatry: psychiatric illness in Taiwan and the United States. The Am J Psychiatry. 1991;148(12):1697–704.

    Article  PubMed  Google Scholar 

  42. Beiser M, Fleming JA. Measuring psychiatric disorder among Southeast Asian refugees. Psychol Med. 1986;16(3):627–39.

    Article  CAS  PubMed  Google Scholar 

  43. 1 NPHN. National epidemiology mental disorder Survey by National Psychiatric Hospital No 1. Ho Chi Minh city, Vietnam: 2002.

  44. Van Nguyen H, Nguyen HLT, Mai HT, Le HQ, Tran BX, Hoang CD, et al. Stigmatization among methadone maintenance treatment patients in mountainous areas in northern Vietnam. Harm Reduct J. 2017;14:1.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Tran BX, Ohinmaa A, Duong AT, Do NT, Nguyen LT, Nguyen QC, et al. Changes in drug use are associated with health-related quality of life improvements among methadone maintenance patients with HIV/AIDS. Qual Life Res. 2012;21:613–23.

    Article  PubMed  Google Scholar 

  46. Tran BX, Ohinmaa A, Nguyen LT. Quality of life profile and psychometric properties of the EQ-5D-5L in HIV/AIDS patients. Health and quality of life outcomes. 2012;10:132.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Tran B, Nguyen L, Ohinmaa A, Maher R, Nong V, Latkin CA. Longitudinal and cross sectional assessments of health utility in adults with HIV/AIDS: a systematic review and meta-analysis. BMC Health Serv Res. 2015;15:7.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Barry DT, Beitel M, Garnet B, Joshi D, Rosenblum A, Schottenfeld RS. Relations among psychopathology, substance use, and physical pain experiences in methadone-maintained patients. J Clin Psychiatry. 2009;70(9):1213–8.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Rosenblum A, Joseph H, Fong C, Kipnis S, Cleland C, Portenoy RK. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. JAMA. 2003;289(18):2370–8.

    Article  PubMed  Google Scholar 

  50. Walter M, Dammann G, Wiesbeck GA, Klapp BF. Psychosocial stress and alcohol consumption: interrelations, consequences and interventions. Fortschr Neurol Psychiatr. 2005;73(9):517–25.

    Article  CAS  PubMed  Google Scholar 

  51. Silberman Y, Bajo M, Chappell AM, Christian DT, Cruz M, Diaz MR, et al. Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol. 2009;43(7):509–19.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  52. Powers RJ, Kutash IL. Stress and alcohol. Int J Addict. 1985;20(3):461–82.

    Article  CAS  PubMed  Google Scholar 

  53. Arthur D. Alcohol-related problems: a critical review of the literature and directions in nurse education. Nurse Educ Today. 1998;18(6):477–87.

    Article  CAS  PubMed  Google Scholar 

  54. Bickel WK, Marion I, Lowinson JH. The treatment of alcoholic methadone patients: a review. J Subst Abuse Treat. 1987;4(1):15–9.

    Article  CAS  PubMed  Google Scholar 

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  1. Long Hoang Nguyen, Bach Xuan Tran and Huong Lan Thi Nguyen have equally contributed to this work.

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    Correspondence to Huong Lan Thi Nguyen.

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    Nguyen, L.H., Tran, B.X., Nguyen, H.L.T. et al. Psychological Distress Among Methadone Maintenance Patients in Vietnamese Mountainous Areas. AIDS Behav 21, 3228–3237 (2017). https://doi.org/10.1007/s10461-017-1779-5

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