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Retention, Antiretroviral Therapy Use and Viral Suppression by History of Injection Drug Use Among HIV-Infected Patients in an Urban HIV Clinical Cohort

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Abstract

Compared to HIV-infected persons who do not inject drugs (non-IDU), persons who inject drugs (PWID) experience disparities in linking to medical care, initiating antiretroviral therapy (ART) and achieving viral suppression. There has been little attention to changes in these disparities over time. We estimated the proportion of PWID and non-IDU retained in care, on ART, and virally suppressed each year from 2001–2012 in the Johns Hopkins HIV Clinical Cohort (JHHCC). We defined active clinic patients as those who had ≥1 clinical visit, CD4 cell count, or viral load between July 1 of the prior year, and June 30 of the analysis year. Within a calendar year, retention was defined as ≥2 clinical visits or HIV-related laboratory measurements >90 days; ART use was defined as ≥1 ART prescription active ≥30 days; and viral suppression was defined as ≥1 HIV viral load <400 copies/mL. While PWID were less likely to be retained in earlier years, the gaps in retention closed around 2010. After 2003–2004, PWID and non-IDU retained in care had similar probability of receiving a prescription for ART and PWID and non-IDU on ART had similar probability of viral suppression.

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Funding

This work was supported by NIH Grants U01 DA036935 and P30 AI094189.

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Authors and Affiliations

  1. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St., Baltimore, MD, 21205, USA

    Catherine R. Lesko, Weiqun Tong, Richard D. Moore & Bryan Lau

  2. School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Richard D. Moore & Bryan Lau

Authors
  1. Catherine R. Lesko
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  2. Weiqun Tong
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  3. Richard D. Moore
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  4. Bryan Lau
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Correspondence to Catherine R. Lesko.

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Conflict of Interest

CRL has received a speaker honorarium from Gilead Sciences, Inc. for work unrelated to this manuscript. No other authors have conflicts of interest to report.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individuals included in this study.

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Lesko, C.R., Tong, W., Moore, R.D. et al. Retention, Antiretroviral Therapy Use and Viral Suppression by History of Injection Drug Use Among HIV-Infected Patients in an Urban HIV Clinical Cohort. AIDS Behav 21, 1016–1024 (2017). https://doi.org/10.1007/s10461-016-1585-5

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  • DOI: https://doi.org/10.1007/s10461-016-1585-5

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