Skip to main content

Advertisement

Log in

Evidence for the Reliability and Validity of the Internalized AIDS-Related Stigma Scale in Rural Uganda

  • Original Paper
  • Published:
AIDS and Behavior Aims and scope Submit manuscript

Abstract

HIV infection remains highly stigmatized throughout sub-Saharan Africa despite the increasing availability of treatment. HIV-related stigma is commonly described to be highly prevalent in East Africa, but none of these studies have employed validated scales for measurement. We used data from 456 people living with HIV/AIDS in rural Uganda to validate the six-item Internalized AIDS-Related Stigma Scale. The scale demonstrated acceptable internal consistency (Cronbach’s alpha = 0.73) and time stability. Exploratory factor analysis indicated the presence of a single factor. Construct validity was supported by observations that the scale was correlated with related constructs such as depression and mental health-related quality of life. The scale was able to discriminate between groups of persons who were different in terms of treatment status and their experience of HIV-related self-blame. Taken together, these findings suggest that the Internalized AIDS-Related Stigma Scale may be a useful tool for socio-behavioral HIV research.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Farmer P, Leandre F, Mukherjee JS, Claude M, Nevil P, Smith-Fawzi MC, et al. Community-based approaches to HIV treatment in resource-poor settings. Lancet. 2001;358(9279):404–9.

    Article  PubMed  CAS  Google Scholar 

  2. Castro A, Farmer P. Understanding and addressing AIDS-related stigma: from anthropological theory to clinical practice in Haiti. Am J Public Health. 2005;95(1):53–9.

    Article  PubMed  Google Scholar 

  3. Wolfe WR, Weiser SD, Leiter K, Steward WT, Percy-de Korte F, Phaladze N, et al. The impact of universal access to antiretroviral therapy on HIV stigma in Botswana. Am J Public Health. 2008;98(10):1865–71.

    Article  PubMed  Google Scholar 

  4. Campbell C, Skovdal M, Madanhire C, Mugurungi O, Gregson S, Nyamukapa C. “We, the AIDS people…”: how antiretroviral therapy enables Zimbabweans living with HIV/AIDS to cope with stigma. Am J Public Health. 2011;101(6):1004–10.

    Article  PubMed  Google Scholar 

  5. Zuch M, Lurie M. ‘A virus and nothing else’: the effect of ART on HIV-related stigma in rural South Africa. AIDS Behav. 2012;16(3):564–70.

    Article  PubMed  Google Scholar 

  6. Medley A, Garcia-Moreno C, McGill S, Maman S. Rates, barriers and outcomes of HIV serostatus disclosure among women in developing countries: implications for prevention of mother-to-child transmission programmes. Bull World Health Organ. 2004;82(4):299–307.

    PubMed  Google Scholar 

  7. Kalichman SC, Simbayi LC, Jooste S, Toefy Y, Cain D, Cherry C, et al. Development of a brief scale to measure AIDS-related stigma in South Africa. AIDS Behav. 2005;9(2):135–43.

    Article  PubMed  Google Scholar 

  8. Wolfe WR, Weiser SD, Bangsberg DR, Thior I, Makhema JM, Dickinson DB, et al. Effects of HIV-related stigma among an early sample of patients receiving antiretroviral therapy in Botswana. AIDS Care. 2006;18(8):931–3.

    Article  PubMed  CAS  Google Scholar 

  9. Roura M, Urassa M, Busza J, Mbata D, Wringe A, Zaba B. Scaling up stigma? The effects of antiretroviral roll-out on stigma and HIV testing. Early evidence from rural Tanzania. Sex Transm Infect. 2009;85(4):308–12.

    Article  PubMed  CAS  Google Scholar 

  10. Simbayi LC, Kalichman SC, Strebel A, Cloete A, Henda N, Mqeketo A. Disclosure of HIV status to sex partners and sexual risk behaviours among HIV-positive men and women, Cape Town, South Africa. Sex Transm Infect. 2007;83(1):29–34.

    Article  PubMed  CAS  Google Scholar 

  11. Young SD, Bendavid E. The relationship between HIV testing, stigma, and health service usage. AIDS Care. 2010;22(3):373–80.

    Article  PubMed  Google Scholar 

  12. Young SD, Hlavka Z, Modiba P, Gray G, Van Rooyen H, Richter L, et al. HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043). J Acquir Immune Defic Syndr. 2010;55(5):620–4.

    Article  PubMed  Google Scholar 

  13. Patel R, Ratner J, Gore-Felton C, Kadzirange G, Woelk G, Katzenstein D. HIV disclosure patterns, predictors, and psychosocial correlates among HIV positive women in Zimbabwe. AIDS Care. 2012;24(3):358–68.

    Article  PubMed  Google Scholar 

  14. Genberg BL, Hlavka Z, Konda KA, Maman S, Chariyalertsak S, Chingono A, et al. A comparison of HIV/AIDS-related stigma in four countries: negative attitudes and perceived acts of discrimination towards people living with HIV/AIDS. Soc Sci Med. 2009;68(12):2279–87.

    Article  PubMed  Google Scholar 

  15. Katz IT, Essien T, Marinda ET, Gray GE, Bangsberg DR, Martinson NA, et al. Antiretroviral therapy refusal among newly diagnosed HIV-infected adults. AIDS. 2011;25(17):2177–81.

    Article  PubMed  Google Scholar 

  16. Earnshaw VA, Chaudoir SR. From conceptualizing to measuring HIV stigma: a review of HIV stigma mechanism measures. AIDS Behav. 2009;13(6):1160–77.

    Article  PubMed  Google Scholar 

  17. Sengupta S, Banks B, Jonas D, Miles MS, Smith GC. HIV interventions to reduce HIV/AIDS stigma: a systematic review. AIDS Behav. 2011;15(6):1075–87.

    Article  PubMed  Google Scholar 

  18. Brown L, Macintyre K, Trujillo L. Interventions to reduce HIV/AIDS stigma: what have we learned? AIDS Educ Prev. 2003;15(1):49–69.

    Article  PubMed  Google Scholar 

  19. Kunihira NR, Nuwaha F, Mayanja R, Peterson S. Barriers to use of antiretroviral drugs in Rakai district of Uganda. Afr Health Sci. 2010;10(2):120–9.

    PubMed  CAS  Google Scholar 

  20. Wyrod R. Masculinity and the persistence of AIDS stigma. Cult Health Sex. 2011;13(4):443–56.

    Article  PubMed  Google Scholar 

  21. Duff P, Kipp W, Wild TC, Rubaale T, Okech-Ojony J. Barriers to accessing highly active antiretroviral therapy by HIV-positive women attending an antenatal clinic in a regional hospital in western Uganda. J Int AIDS Soc. 2010;13:37.

    Article  PubMed  Google Scholar 

  22. Green HD Jr., Atuyambe L, Ssali S, Ryan GW, Wagner GJ. Social networks of PLHA in Uganda: implications for mobilizing PLHA as agents for prevention. AIDS Behav. 2011;15(5):992–1002.

    Article  PubMed  Google Scholar 

  23. Medley AM, Kennedy CE, Lunyolo S, Sweat MD. Disclosure outcomes, coping strategies, and life changes among women living with HIV in Uganda. Qual Health Res. 2009;19(12):1744–54.

    Article  PubMed  Google Scholar 

  24. Theilgaard ZP, Katzenstein TL, Chiduo MG, Pahl C, Bygbjerg IC, Gerstoft J, et al. Addressing the fear and consequences of stigmatization—a necessary step towards making HAART accessible to women in Tanzania: a qualitative study. AIDS Res Ther. 2011;8:28.

    Article  PubMed  CAS  Google Scholar 

  25. Amuri M, Mitchell S, Cockcroft A, Andersson N. Socio-economic status and HIV/AIDS stigma in Tanzania. AIDS Care. 2011;23(3):378–82.

    Article  PubMed  Google Scholar 

  26. Ostermann J, Reddy EA, Shorter MM, Muiruri C, Mtalo A, Itemba DK, et al. Who tests, who doesn’t, and why? Uptake of mobile HIV counseling and testing in the Kilimanjaro region of Tanzania. PLoS One. 2011;6(1):e16488.

    Article  PubMed  CAS  Google Scholar 

  27. Holzemer WL, Uys LR, Chirwa ML, Greeff M, Makoae LN, Kohi TW, et al. Validation of the HIV/AIDS stigma instrument—PLWA (HASI-P). AIDS Care. 2007;19(8):1002–12.

    Article  PubMed  Google Scholar 

  28. Kalichman SC, Simbayi LC, Cloete A, Mthembu PP, Mkhonta RN, Ginindza T. Measuring AIDS stigmas in people living with HIV/AIDS: the Internalized AIDS-Related Stigma Scale. AIDS Care. 2009;21(1):87–93.

    Article  PubMed  Google Scholar 

  29. Steward WT, Herek GM, Ramakrishna J, Bharat S, Chandy S, Wrubel J, et al. HIV-related stigma: adapting a theoretical framework for use in India. Soc Sci Med. 2008;67(8):1225–35.

    Article  PubMed  Google Scholar 

  30. Berger BE, Ferrans CE, Lashley FR. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24(6):518–29.

    Article  PubMed  CAS  Google Scholar 

  31. Derogatis LR, Lipman RS, Rickels K, Uhlenhuth EH, Covi L. The Hopkins Symptom Checklist (HSCL): a self-report symptom inventory. Behav Sci. 1974;19(1):1–15.

    Article  PubMed  CAS  Google Scholar 

  32. Bolton P, Ndogoni L. Cross-cultural assessment of trauma-related mental illness (Phase II): a report of research conducted by World Vision Uganda and The Johns Hopkins University. 2001. http://www.certi.org/publications/policy/ugandafinahreport.htm. Accessed 23 April 2011.

  33. Wu AW, Rubin HR, Mathews WC, Ware JE Jr., Brysk LT, Hardy WD, et al. A health status questionnaire using 30 items from the Medical Outcomes Study. Preliminary validation in persons with early HIV infection. Med Care. 1991;29(8):786–98.

    Article  PubMed  CAS  Google Scholar 

  34. Revicki DA, Sorensen S, Wu AW. Reliability and validity of physical and mental health summary scores from the Medical Outcomes Study HIV Health Survey. Med Care. 1998;36(2):126–37.

    Article  PubMed  CAS  Google Scholar 

  35. Wu AW, Revicki DA, Jacobson D, Malitz FE. Evidence for reliability, validity and usefulness of the Medical Outcomes Study HIV Health Survey (MOS-HIV). Qual Life Res. 1997;6(6):481–93.

    Article  PubMed  CAS  Google Scholar 

  36. Kling JR, Liebman JB, Katz LF. Experimental analysis of neighborhood effects. Econometrica. 2007;75(1):83–119.

    Article  Google Scholar 

  37. Cattell RB. The scree test for the number of factors. Multivar Behav Res. 1966;1(2):245–76.

    Article  Google Scholar 

  38. Floyd FJ, Widaman KF. Factor analysis in the development and refinement of clinical assessment instruments. Psychol Assess. 1995;7(3):286–99.

    Article  Google Scholar 

  39. Shrout PE, Fleiss JL. Intraclass correlations: uses in assessing rater reliability. Psychol Bull. 1979;86(2):420–8.

    Article  PubMed  CAS  Google Scholar 

  40. Simbayi LC, Kalichman S, Strebel A, Cloete A, Henda N, Mqeketo A. Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa. Soc Sci Med. 2007;64(9):1823–31.

    Article  PubMed  Google Scholar 

  41. Chaudoir SR, Norton WE, Earnshaw VA, Moneyham L, Mugavero MJ, Hiers KM. Coping with HIV stigma: do proactive coping and spiritual peace buffer the effect of stigma on depression? AIDS Behav. 2011. doi:10.1007/s10461-011-0039-3.

  42. Rao D, Feldman BJ, Fredericksen RJ, Crane PK, Simoni JM, Kitahata MM, et al. A structural equation model of HIV-related stigma, depressive symptoms, and medication adherence. AIDS Behav. 2012;16(3):711–6.

    Article  PubMed  Google Scholar 

  43. Rueda S, Gibson K, Rourke SB, Bekele T, Gardner S, Cairney J. Mastery moderates the negative effect of stigma on depressive symptoms in people living with HIV. AIDS Behav. 2012;16(3):690–9.

    Article  PubMed  Google Scholar 

  44. Li L, Lee SJ, Thammawijaya P, Jiraphongsa C, Rotheram-Borus MJ. Stigma, social support, and depression among people living with HIV in Thailand. AIDS Care. 2009;21(8):1007–13.

    Article  PubMed  Google Scholar 

  45. Grov C, Golub SA, Parsons JT, Brennan M, Karpiak SE. Loneliness and HIV-related stigma explain depression among older HIV-positive adults. AIDS Care. 2012;22(5):630–9.

    Google Scholar 

  46. Logie C, Gadalla TM. Meta-analysis of health and demographic correlates of stigma towards people living with HIV. AIDS Care. 2009;21(6):742–53.

    Article  PubMed  CAS  Google Scholar 

  47. Cronbach LJ, Meehl PE. Construct validity in psychological tests. Psychol Bull. 1955;52(4):281–302.

    Article  PubMed  CAS  Google Scholar 

  48. Walton DA, Farmer PE, Lambert W, Leandre F, Koenig SP, Mukherjee JS. Integrated HIV prevention and care strengthens primary health care: lessons from rural Haiti. J Public Health Policy. 2004;25(2):137–58.

    Article  PubMed  Google Scholar 

  49. Seeley J, Russell S. Social rebirth and social transformation? Rebuilding social lives after ART in rural Uganda. AIDS Care. 2010;22(Suppl 1):44–50.

    Article  PubMed  Google Scholar 

  50. Russell S, Seeley J. The transition to living with HIV as a chronic condition in rural Uganda: working to create order and control when on antiretroviral therapy. Soc Sci Med. 2010;70(3):375–82.

    Article  PubMed  Google Scholar 

  51. Blower S, Ma L, Farmer P, Koenig S. Predicting the impact of antiretrovirals in resource-poor settings: preventing HIV infections whilst controlling drug resistance. Curr Drug Targets Infect Disord. 2003;3(4):345–53.

    Article  PubMed  CAS  Google Scholar 

  52. Koenig SP, Leandre F, Farmer PE. Scaling-up HIV treatment programmes in resource-limited settings: the rural Haiti experience. AIDS. 2004;18(Suppl 3):S21–5.

    Article  PubMed  Google Scholar 

  53. Tiruneh YM. Refashioning stigma: experiencing and managing HIV/AIDS in the biomedical era. In: Klein H, Merrick J, editors. Human Immunodeficiency Virus (HIV) Research: Social Science Aspects. New York, NY: Nova Science; 2012.

  54. Steward WT, Chandy S, Singh G, Panicker ST, Osmand TA, Heylen E, et al. Depression is not an inevitable outcome of disclosure avoidance: HIV stigma and mental health in a cohort of HIV-infected individuals from Southern India. Psychol Health Med. 2011;16(1):74–85.

    Article  PubMed  Google Scholar 

  55. Tsai AC, Bangsberg DR, Frongillo EA, Hunt PW, Muzoora C, Martin JN, et al. Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda. Soc Sci Med. 2012;74(12):2012–9.

    Article  PubMed  Google Scholar 

  56. Turan JM, Bukusi EA, Onono M, Holzemer WL, Miller S, Cohen CR. HIV/AIDS stigma and refusal of HIV testing among pregnant women in rural Kenya: results from the MAMAS Study. AIDS Behav. 2011;15(6):1111–20.

    Article  PubMed  Google Scholar 

  57. Mshana GH, Wamoyi J, Busza J, Zaba B, Changalucha J, Kaluvya S, et al. Barriers to accessing antiretroviral therapy in Kisesa, Tanzania: a qualitative study of early rural referrals to the national program. AIDS Patient Care STDS. 2006;20(9):649–57.

    Article  PubMed  Google Scholar 

  58. Murray LK, Semrau K, McCurley E, Thea DM, Scott N, Mwiya M, et al. Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women: a qualitative study. AIDS Care. 2009;21(1):78–86.

    Article  PubMed  Google Scholar 

  59. Fox MP, Mazimba A, Seidenberg P, Crooks D, Sikateyo B, Rosen S. Barriers to initiation of antiretroviral treatment in rural and urban areas of Zambia: a cross-sectional study of cost, stigma, and perceptions about ART. J Int AIDS Soc. 2010;13:8.

    Article  PubMed  Google Scholar 

  60. Ware NC, Idoko J, Kaaya S, Biraro IA, Wyatt MA, Agbaji O, et al. Explaining adherence success in sub-Saharan Africa: an ethnographic study. PLoS Med. 2009;6(1):e11.

    Article  PubMed  Google Scholar 

  61. Ware NC, Wyatt MA, Tugenberg T. Social relationships, stigma and adherence to antiretroviral therapy for HIV/AIDS. AIDS Care. 2006;18(8):904–10.

    Article  PubMed  CAS  Google Scholar 

  62. Weiser S, Wolfe W, Bangsberg D, Thior I, Gilbert P, Makhema J, et al. Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana. J Acquir Immune Defic Syndr. 2003;34(3):281–8.

    Article  PubMed  Google Scholar 

  63. Link BG, Phelan JC. Conceptualizing stigma. Annu Rev Sociol. 2001;27(1):363–85.

    Article  Google Scholar 

Download references

Acknowledgments

We thank the Uganda AIDS Rural Treatment Outcomes study participants who made this study possible by sharing their experiences; and Doreen Akello, Marcy Mutumba, Christine Ngabirano, Ruth Ssentongo, and Florence Turyashemererwa for research assistance. Jessica E. Haberer, Elias Kumbakumba, and Jude Senkungu provided invaluable input on all aspects of study design and implementation. While these individuals are acknowledged for their assistance, no endorsement of manuscript contents or conclusions should be inferred.

Funding

The study was funded by U.S. National Institutes of Health R01 MH-054907, K23 MH-79713, and P30 AI27763. The authors acknowledge the following additional sources of salary support: the Burke Family Foundation, K23 MH-096620, and K24 MH-087227.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alexander C. Tsai.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tsai, A.C., Weiser, S.D., Steward, W.T. et al. Evidence for the Reliability and Validity of the Internalized AIDS-Related Stigma Scale in Rural Uganda. AIDS Behav 17, 427–433 (2013). https://doi.org/10.1007/s10461-012-0281-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10461-012-0281-3

Keywords

Navigation