Abstract
Complete atrioventricular block (type III AVB) is characterized by an absence of P wave transmission to ventricles. This implies that QRS complexes are generated in an autonomous way and are not coordinated with P waves. This work introduces a new algorithm for the detection of P waves for this type of pathology using noninvasive electrocardiographic surface leads. The proposed algorithm is divided into three stages. In the first stage, the R waves located by a QRS detector are used to generate the RR series and time references for the other stages of the algorithm. In the second stage, the ventricular activity (QT segment) is removed by using an adaptive filter that obtains an averaged pattern of the QT segment. In the third stage, a new P wave detector is applied to the residual signal obtained after QT cancellation in order to detect P wave locations and get the PP time series. Eight Holter records from patients with congenital type III AVB were used to verify the proposed algorithm. Although further improvements should be made to improve the algorithm’s performance, the results obtained show high average values of sensitivity (90.52%) and positive prediction (90.98%).
Similar content being viewed by others
References
Abboud S., G. Barkai, S. Mashiach, D. Sadeh 1990 Quantification of the fetal electrocardiogram using averaging technique. Comput. Biol. Med. 20:147–155
Almenar V., A. Albiol 1999 A new adaptive scheme for ECG enhancement. Signal. Process. 75:253–263
Chorro, F. J., J. F. Guerrero, J. Calpe, E. Dalli, M. Burguera, M. Bataller, P. Malo, J. Sanchis, J. Espí, and V. López-Merino. Análisis espectral de la variabilidad de la frecuencia cardíaca en el bloqueo A-V completo de origen congénito. Rev. Lat. Cardiol. 16:12–18, 1995
Ciaccio E. J., E. Micheli-Tzanakou 2007 Development of gradient descent adaptive algorithms to remove common mode artifact for improvement of cardiovascular signal quality. Ann. Biomed. Eng. 35:1146–1155
Clarkson, P. M. Optimal and Adaptive Signal Processing. Boca Raton, FL: CRC Press, 1993, 529 pp
Conover, M. Understanding Electrocardiography. St. Louis: Mosby, 2002
Ferrara E. R., B. Widrow 1982 Fetal electrocardiogram enhancement by time-sequenced adaptive filtering. IEEE Trans. Biomed. Eng. 29:458–460
Guerrero J. F., M. Martinez, M. Bataller, J. R. Magdalena 2006 A new algorithm for foetal QRS detection in surface abdominal records. Comput. Cardiol. 33:441–444
Hampton, J. R. The ECG Made Easy. Edinburgh: Churchill Livingstone, 1998, 129 pp.
Joeng, H.-K., K.-K. Kim, S.-C. Hwang, and M.-H. Lee. A new algorithm for P-wave detection in the ECG signal. Engineering in Medicine and Biology Society, 1989. Images of the twenty-first century. In: Proceedings of the Annual International Conference of the IEEE Engineering, Vol. 1, 1989, pp. 42–43
Hsiao H. C., H. W. Chiu, S. C. Lee, T. Kao, H. Y. Chang, C. W. Kong 1998 Esophageal PP intervals for analysis of short-term heart rate variability in patients with atrioventricular block before and after insertion of a temporary ventricular inhibited pacemaker. Int. J. Cardiol. 64:271–276
Jane R., H. Rix, P. Caminal, P. Laguna 1991 Alignment methods for averaging of high-resolution cardiac signals: a comparative study of performance. IEEE Trans. Biomed. Eng. 38:571–579
Jeras, M., R. Magjarevic, and E. Pacelat. Real time P-wave detection in surface ECG. In: IFMBE Proceedings MEDICOM, 2001, pp. 405–408
Kaiser, J. F. Some useful properties of Teager’s energy operators. In: ICASSP-93, Vol. 3, 1993, pp. 149–152
Kim K., Y. H. Lee, H. Kwon, J. M. Kim, I. S. Kim, Y. K. Park 2004 Averaging algorithm based on data statistics in magnetocardiography. Neurol. Clin. Neurophysiol. 2004:42
Laguna P., R. Jane, O. Meste, P. W. Poon, P. Caminal, H. Rix, N. V. Thakor 1992 Adaptive filter for event-related bioelectric signals using an impulse correlated reference input: comparison with signal averaging techniques. IEEE Trans. Biomed. Eng. 39:1032–1044
Laguna P., N. V. Thakor, P. Caminal, R. Jane, H. R. Yoon, A. Bayes, de Luna, V. Marti, J. Guindo 1990 New algorithm for QT interval analysis in 24-hour Holter ECG: performance and applications. Med. Biol. Eng. Comput. 28:67–73
Martinez M., E. Soria, J. Calpe, J. F. Guerrero, J. R. Magdalena 1997 Application of the adaptive impulse correlated filter for recovering fetal electrocardiogram. Comput. Cardiol. 1997:9–12
Michaelsson M., M. A. Engle 1972 Congenital complete heart block: an international study of the natural history. Cardiovasc. Clin. 4:85–101
Michaelsson M., A. Jonzon, T. Riesenfeld 1995 Isolated congenital complete atrioventricular block in adult life. A prospective study. Circulation 92:442–449
Motte, G., S. Dinanian, and C. Sebag. Classification and pitfalls of atrioventricular blocks. Arch. Mal. Coeur. Vaiss. 90(Spec No. 1):47–55, 1997
Mukhopadhyay S., G. C. Ray 1998 A new interpretation of nonlinear energy operator and its efficacy in spike detection. IEEE Trans. Biomed. Eng. 45:180–187
Pan J., W. J. Tompkins 1985 A real-time QRS detection algorithm. IEEE Trans. Biomed. Eng. 32:230–236
Park, M. K., and W. G. Guntheroth. How to read pediatric ECG’s. St. Louis: Mosby-Year Book Inc., 1992, 248 pp
Sahambi J. S., S. N. Tandon, R. K. Bhatt 1997 Using wavelet transforms for ECG characterization. An on-line digital signal processing system. IEEE Eng. Med. Biol. Mag. 16:77–83
Shouldice, R., C. Heneghan, P. Nolan, and P. G. Nolan. PR and PP ECG intervals as indicators of autonomic nervous innervation of the cardiac sinoatrial and atrioventricular nodes. In: EMBS Conference, 2003, pp. 261–264
Sternickel K. 2002 Automatic pattern recognition in ECG time series. Comput. Methods Progr. Biomed. 68:109–115
Stridh M., L. Sornmo 2001 Spatiotemporal QRST cancellation techniques for analysis of atrial fibrillation. IEEE Trans. Biomed. Eng. 48:105–111
Thakor N. V., Y. S. Zhu 1991 Applications of adaptive filtering to ECG analysis: noise cancellation and arrhythmia detection. IEEE Trans. Biomed. Eng. 38:785–794
Van Alste J. A., T. S. Schilder 1985 Removal of base-line wander and power-line interference from the ECG by an efficient FIR filter with a reduced number of taps. IEEE Trans. Biomed. Eng. 32:1052–1060
Widrow, B., J. R. Glover Jr., J. M. McCool, J. Kaunitz, C. S. Williams, R. H. Hearn, J. R. Zeidler, J. Eugene Dong, and R. C. Goodlin. Adaptive noise cancelling: principles and applications. Proc. IEEE 63:1692–1716, 1975
Zarzoso V., A. K. Nandi, E. Bacharakis 1997 Maternal and foetal ECG separation using blind source separation methods. IMA J. Math. Appl. Med. Biol. 14:207–225
Acknowledgments
We thank Dr. Ernesto Dallí from the Cardiology Service of Arnau de Vilanova Hospital (Valencia, Spain) for the selection of the records utilized in the study. The authors gratefully acknowledge the critical and helpful advice of the referees to make the paper more clear and concise.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Guerrero, J., Martínez, M., Magdalena, R. et al. P and R Wave Detection in Complete Congenital Atrioventricular Block. Ann Biomed Eng 37, 94–106 (2009). https://doi.org/10.1007/s10439-008-9596-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10439-008-9596-7