Skip to main content

Advertisement

SpringerLink
Log in

Effect of Food Consistency on the Degree of Mineralization in the Rat Mandible

  • Published:
Annals of Biomedical Engineering Aims and scope Submit manuscript

Abstract

A switch to a soft diet, associated with reduced forces applied to the mandible during mastication, may result in an alteration of the degree of mineralization in the mandible. This alteration may be regionally different. The aim of this study was to analyze this alteration by examination of the degree of mineralization in the mandible of growing rats fed with a hard or soft diet. Fifteen Wistar male rats were used in this investigation. After weaning, six rats were fed with a hard diet and the remaining nine rats with a soft diet. After 9 weeks, three-dimensional reconstructions of the cortical and trabecular bone of their mandibles were obtained using a microCT system. The degree of mineralization was determined for the trabecular bone in the condyle and for the cortical bone in the anterior and posterior areas of the mandibular body. In both diet groups the degree of mineralization was significantly (p < 0.01) lower in the trabecular than in the cortical bone. In the mandibular body, the anterior area showed a significantly (p < 0.01) higher degree of mineralization than the posterior area in both diet groups. In both areas the soft diet group had a significantly (p < 0.05 or 0.01) higher degree of mineralization than the hard diet group. The trabecular bone in the condyle of the hard diet group showed a significantly (p < 0.01) higher degree of mineralization than in the soft diet group. The present results indicate the importance of proper masticatory muscle function for craniofacial growth and development.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

References

  1. Berger E. H., J. Klein-Nulend, J. P. Veldhuijzen Mechanical stress and osteogenesis in vitro. J. Bone Miner. Res. 2:S397–401, 1992

    Google Scholar 

  2. Bouvier M., W. L. Hylander The effect of dietary consistency on gross and histologic morphology in the craniofacial region of young rats. Am. J. Anat. 170:117–126, 1984

    Article  PubMed  CAS  Google Scholar 

  3. Bouvier M., M. L. Zimny Effects of mechanical loads on surface morphology of the condylar cartilage of the mandible in rats. Acta Anat. 129:293–300, 1987

    Article  PubMed  CAS  Google Scholar 

  4. Ciochon R. L., R. A. Nisbett, R. S. Corruccini Dietary consistency and craniofacial development related to masticatory function in minipigs. J. Craniofacial Genet. Dev. Biol. 17:96–102, 1997

    CAS  Google Scholar 

  5. Ding M., A. Odgard, I. Hvid Accuracy of cancellous bone volume fraction measured by micro-CT scanning. J. Biomech. 32:323–326, 1999

    Article  PubMed  CAS  Google Scholar 

  6. Hamrick M. W., C. Pennington, C. Byron Bone remodeling and disc degeneration in the lumbar spine of mice lacking GDF8 (myostatin). J. Orthop. Res. 21: 1025–1032, 2003

    Article  PubMed  CAS  Google Scholar 

  7. He T., S. Kiliaridis Effects of masticatory muscle function on craniofacial morphology in growing ferrets (Mustela putorius furo). Eur. J. Oral Sci. 111:510–517, 2003

    Article  PubMed  Google Scholar 

  8. Katsaros C., R. Berg, S. Kiliaridis Influence of masticatory muscle function on transverse skull dimensions in the growing rat. J. Orofac. Orthop. 63:5–13, 2002

    Article  PubMed  Google Scholar 

  9. Kiliaridis S. Masticatory muscle influence on craniofacial growth. Acta Odontol. Scand. 53:196–202, 1995

    PubMed  CAS  Google Scholar 

  10. Koolstra J. H., T. M. G. J. van Eijden Prediction of volumetric strain in the human temporomandibular joint cartilage during jaw movement. J. Anat. 209:369–380, 2006

    Article  PubMed  CAS  Google Scholar 

  11. Langenbach G. E. J., W. A. Weijs Growth patterns of the rabbit masticatory muscles. J. Dent. Res. 69:20–25, 1990

    PubMed  CAS  Google Scholar 

  12. Langenbach G. E. J., W. A. Weijs, P. Brugman, T. M. G. J. van Eijden A longitudinal electromyographic study of the postnatal maturation of mastication in the rabbit. Arch. Oral Biol. 46: 811–820, 2001

    Article  PubMed  CAS  Google Scholar 

  13. Mavropoulos A., S. Kiliaridis, A. Bresin, P. Ammann Effect of different masticatory functional and mechanical demands on the structural adaptation of the mandibular alveolar bone in young growing rats. Bone 35:191–197, 2004

    Article  PubMed  CAS  Google Scholar 

  14. Mavropoulos A., P. Ammann, A. Bresin, S. Kiliaridis Masticatory demands induce region-specific changes in mandibular bone density in growing rats. Angle Orthod. 75:625–630, 2005

    PubMed  Google Scholar 

  15. Meunier P. J., G. Boivin Bone mineral density reflects bone mass but also the degree of mineralization of bone: therapeutic implications. Bone 21:373–377, 1997

    Article  PubMed  CAS  Google Scholar 

  16. Mulder L., J. H. Koolstra, T. M. G. J. van Eijden Accuracy of microCT in the quantitative determination of the degree and distribution of mineralization in developing bone. Acta Radiol. 45:769–777, 2004

    Article  PubMed  CAS  Google Scholar 

  17. Mulder L., J. H. Koolstra, W. A. Weijs, T. M. G. J. van Eijden Architecture and mineralization of developing trabecular bone in the pig mandibular condyle. Anat. Rec. A. Discov. Mol. Cell Evol. Biol. 285: 659–666, 2005

    PubMed  Google Scholar 

  18. Mulder L., L. B. van Groningen, Y. A. Potgieser, J. H. Koolstra, T. M. G. J. van Eijden Regional differences in architecture and mineralization of developing mandibular bone. Anat. Rec. A Discov. Mol. Cell Evol. Biol. 288:954–961, 2006

    PubMed  Google Scholar 

  19. Nicholson E. K., S. R. Stock, M. W. Hamrick, M. J. Ravosa Biomineralization and adaptive plasticity of the temporomandibular joint in myostatin knockout mice. Arch. Oral Biol. 51: 37–49, 2006

    Article  PubMed  CAS  Google Scholar 

  20. Nuzzo S., F. Peyrin, P. Cloetens, J. Baruchel, G. Boivin. Quantification of the degree of mineralization in three dimensions using synchrotron radiation microtomography. Med. Phys. 29:2676–2681, 2002

    Article  Google Scholar 

  21. Raadsheer M. C., S. Kiliaridis, T. M. G. J. van Eijden, F. C. van Ginkel, B. Prahl-Andersen Masseter muscle thickness in growing individuals and its relation to facial morphology. Arch. Oral Biol. 41:323–332, 1996

    Article  PubMed  CAS  Google Scholar 

  22. Ravosa M. J., E. B. Klopp, J. Pinchoff, S. R. Stock, M. W. Hamrick Plasticity of mandibular biomineralization in myostatin-deficient mice. J. Morphol. 268:275–282, 2007

    Article  PubMed  Google Scholar 

  23. Reid S. A., A. Boyde Changes in the mineral density distribution in human bone with age: image analysis using backscattered electrons in the SEM. J. Bone Miner. Res. 2:13–22, 1987

    Article  PubMed  CAS  Google Scholar 

  24. Renders G. A. P., L. Mulder, L. J. van Ruijven, T. M. G. J. van Eijden Degree and distribution of mineralization in the human mandibular condyle. Calcif. Tissue Int. 79:190–196, 2006

    Article  PubMed  CAS  Google Scholar 

  25. Tanaka E., N. Kawai, M. Tanaka, M. Todoh, T. van Eijden, K. Hanaoka, A. D. Dalla-Bona, T. Takata, K. Tanne The frictional coefficient of the temporomandibular joint and its dependency on the magnitude and duration of joint loading. J. Dent. Res. 83: 404–407, 2004

    Article  PubMed  CAS  Google Scholar 

  26. Ulgen M., S. Baran, H. Kaya, I. Karadede The influence of the masticatory hypofunction on the craniofacial growth and development in rats. Am. J. Orthod. Dentofacial Orthop. 111:189–198, 1997

    Article  PubMed  CAS  Google Scholar 

  27. van Eijden T. M. G. J. Biomechanics of the mandible. Crit. Rev. Oral Biol. Med. 11: 123–136, 2000

    PubMed  Google Scholar 

  28. van Ruijven L. J., E. B. W. Giesen, L. Mulder, M. Ferella, T. M. G. J. van Eijden The effect of bone loss on rod-like and plate-like trabeculae in the cancellous bone of the mandibular condyle. Bone 36:1078–1085, 2005

    Article  PubMed  Google Scholar 

  29. van Ruijven, L. J., L. Mulder, and T. M. G. J. van Eijden. Variations in mineralization affect the stress and strain distributions in cortical and trabecular bone. J. Biomech. 40:1211–1218, 2007

    Article  PubMed  Google Scholar 

  30. van Wessel T., G. E. J. Langenbach, P. Brugman, J. A. M. Korfage, T. M. G. J. van Eijden Daily activity of the rabbit jaw muscles during early postnatal development. Neuroscience 40: 137–146, 2006

    Google Scholar 

  31. Yamamoto S. The effects of food consistency on maxillary growth in rats. Eur. J. Orthod. 18:601–615, 1996

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

The authors gratefully thank Dr. Leo van Ruijven for his constructive comments on the manuscript. This research was institutionally supported by the Interuniversity Research School of Dentistry, through the Academic Centre for Dentistry Amsterdam (ACTA).

Author information

Authors and Affiliations

  1. Department of Orthodontics and Craniofacial Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan

    Eiji Tanaka, Ryota Sano, Nobuhiko Kawai & Kazuo Tanne

  2. Department of Functional Anatomy, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands

    Geerling E. J. Langenbach, Peter Brugman & Theo M. G. J. van Eijden

Authors
  1. Eiji Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ryota Sano
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nobuhiko Kawai
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Geerling E. J. Langenbach
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Peter Brugman
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Kazuo Tanne
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Theo M. G. J. van Eijden
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Eiji Tanaka.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tanaka, E., Sano, R., Kawai, N. et al. Effect of Food Consistency on the Degree of Mineralization in the Rat Mandible. Ann Biomed Eng 35, 1617–1621 (2007). https://doi.org/10.1007/s10439-007-9330-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10439-007-9330-x

Keywords

Search

Navigation