Abstract
Quinocitrinines and ergot alkaloids were synthesized by the strain Penicillium citrinum VKM FW-800 as the culture grews. The major part of these secondary metabolites was secreted into the medium. In the phase of growth deceleration, these metabolites were partly absorbed by the producer cells. Zinc ions stimulated both the primary and secondary metabolic processes. Addition of this microelement into the culture medium stimulated biomass accumulation and the synthesis of clavine alkaloids and quinocitrinines.
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Translated from Prikladnaya Biokhimiya i Mikrobiologiya, Vol. 41, No. 5, 2005, pp. 568–572.
Original Russian Text Copyright © 2005 by Kozlovsky, Zhelifonova, Antipova.
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Kozlovsky, A.G., Zhelifonova, V.P. & Antipova, T.V. The Fungus Penicillium citrinum, Isolated from Permafrost Sediments, as a Producer of Ergot Alkaloids and New Quinoline Alkaloids Quinocitrinines. Appl Biochem Microbiol 41, 499–502 (2005). https://doi.org/10.1007/s10438-005-0090-9
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DOI: https://doi.org/10.1007/s10438-005-0090-9