Abstract
Two-dimensional paper networks (2DPNs) hold great potential for transcending the capabilities and performance of today’s paper-based analytical devices. Specifically, 2DPNs enable sophisticated multi-step chemical processing sequences for sample pretreatment and analysis at a cost and ease-of-use that make them appropriate for use in settings with low resources. A quantitative understanding of flow in paper networks is essential to realize the potential of these networks. In this report, we provide a framework for understanding flow in simple 2DPNs using experiments, analytical expressions, and computational simulations.
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Notes
Though nitrocellulose is not formed in the manner traditionally used for papermaking, and may not be considered by some to be a true paper, here we use a more inclusive definition of paper with respect to 2DPNs that includes related thin porous materials.
Note that electrophoresis was not an issue with respect to transport of the pulse of tracer species due to the upstream placement of both electrodes.
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Acknowledgments
We thank Benedict Hui for assistance with the fabrication of 2DPNs. We gratefully acknowledge the support of NIH Grant No. 1RC1EB010593.
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Fu, E., Ramsey, S.A., Kauffman, P. et al. Transport in two-dimensional paper networks. Microfluid Nanofluid 10, 29–35 (2011). https://doi.org/10.1007/s10404-010-0643-y
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DOI: https://doi.org/10.1007/s10404-010-0643-y