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Is the unaffected eye really unaffected? Color Doppler ultrasound findings in unilaterally active central serous chorioretinopathy

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Abstract

Purpose

To evaluate ocular hemodynamic changes using color Doppler ultrasonography imaging (CDI) with an emphasis on unaffected eyes of patients with central serous chorioretinopathy (CSC).

Methods

Twenty-seven patients with active CSC and 25 controls were analyzed using spectral domain-optical coherence tomography (SD-OCT) and CDI for choroidal imaging and evaluation of retrobulbar vessels, respectively.

Results

Resistive index (RI), pulsatility index (PI), and peak systolic velocity (PSV) of the ophthalmic artery (OA) and PSV, end-diastolic velocity (EDV), and mean velocity (Vmean) of the central retinal artery (CRA) in the patient group were less than those in the control group. RI and PI of the CRA were greater in the patient group compared to the control group. RI, PI, PSV, and Vmean of the OA and PSV, EDV, and Vmean of the CRA in the patients’ unaffected eyes were less than those in the control group. OCT measurements of central choroidal thickness (CCT) of the affected eyes in the patient group were significantly greater than those of the unaffected eyes in the patient and control groups; that of the unaffected eyes was greater than that in the control group.

Conclusions

Hemodynamic changes in OA reflect choroidal hyperperfusion. Hemodynamic and OCT changes in the unaffected eyes of the patient group suggest CSC as a bilateral disorder and the systemic nature of the disease. Further investigations may aid in the evaluation of treatment response and the follow-up of disease, providing a new insight into management strategies.

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Author information

Authors and Affiliations

  1. Department of Radiology, Antalya Training and Research Hospital, Antalya, Turkey

    Iclal Erdem Toslak, Bulent Cekic & Mehtap Barc Ergun

  2. Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey

    Muhammet Kazim Erol & Devrim Toslak

  3. Department of Radiology, Loyola University Medical Center, 2160 S 1st Ave, Maywood, IL, 60153, USA

    Iclal Erdem Toslak & Jennifer E. Lim-Dunham

Authors
  1. Iclal Erdem Toslak
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  2. Muhammet Kazim Erol
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  3. Devrim Toslak
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  4. Bulent Cekic
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  5. Mehtap Barc Ergun
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  6. Jennifer E. Lim-Dunham
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Corresponding author

Correspondence to Iclal Erdem Toslak.

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Funding

This research was NOT supported by any foundation organization. No sponsor played a role in the design or conduct of this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants of this study.

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Cite this article

Erdem Toslak, I., Erol, M.K., Toslak, D. et al. Is the unaffected eye really unaffected? Color Doppler ultrasound findings in unilaterally active central serous chorioretinopathy. J Med Ultrasonics 44, 173–181 (2017). https://doi.org/10.1007/s10396-016-0762-5

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  • DOI: https://doi.org/10.1007/s10396-016-0762-5

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