Abstract
To clarify the potential of a novel system using the acoustic impedance difference imaging (AIDI) method for diagnosis of skin disorders, we used it on a coin and swine skin. An ultrasound wave with a central frequency of 20 MHz, emitted from a fused quartz rod with a diameter of 1.25 mm, was focused on the surface of the coin and skin samples. The difference in acoustic impedance was determined by the reflection-type interference-based acoustic impedance measurement method. The processed data were produced as greyscale images on which the maximum measured amplitudes were mapped. We applied the method to a coin. Swine skin, burned and covered with an acrylic sheet with a thickness of 0.2 mm (a few times the half-wavelength) to eliminate the undulations of the skin surface, was employed to obtain processed images from which undulation data were excluded. All the processed images obtained corresponded almost exactly with the magnified optical ones. In the processed images of swine skin, a marked difference was found after the burning procedure. The processed images obtained using the AIDI method reflected not only the undulations but also other information such as elasticity. In conclusion, our system using AIDI has the potential to become a useful modality for the diagnosis of skin disorders.
References
Shigemoto H, Sugimoto T, Hachiya H, Ebara M, Fukuda H, Kato K, Ando H. Measurement of acoustic property distributions of diseased heart and liver tissues. Jpn J Appl Phys. 2001;40:3907–11.
Fujii Y, Taniguchi N, Itoh K, Shigeta K, Wang Y, Tsao JW, Kumasaki K, Itoh T. A new method for attenuation coefficient measurement in the liver: comparison with the spectral-shift central-frequency method. J Ultrason Med. 2002;21:783–8.
Fujii Y, Taniguchi N, Akiyama I, Tsao JW, Itoh K. A new system for in vivo assessment of the degree of nonlinear generation using the second harmonic component in echo signals. Ultrasound Med Biol. 2004;30:1511–6.
Yamaguchi T, Hachiya H. Proposal of a parametric imaging method for quantitative diagnosis of liver fibrosis. J Med Ultrason. 2010;37:155–66.
Moriya T, Furumoto Y, Tagawa N. A simple method of measuring complex acoustic impedance of biological tissues using a fused quartz rod as a transmission line. In: 1998 IEEE Ultrasonic Symposium; 1998. p. 1389–92.
Hatakeyama R, Yoshizawa M, Moriya T. A method for the measurement of acoustic impedance and speed of sound in a small region of bone using a fused quartz rod as a transmission line. Jpn J Appl Phys. 2000;39:6449–54.
Yoshizawa M, Komiya Y, Moriya T. Transducer vibration method for interference-based reflection-type in vivo measurement for acoustic impedance of bone. Jpn J Appl Phys. 2006;45:4703–5.
Yoshizawa M, Irie T, Itoh K, Moriya T. Imaging method for acoustic impedance difference for puncture needle-type ultrasonography using a thin rod with focusing end face. Jpn J Appl Phys. 2008;47:4176–9.
Gropper CA, Stiller MJ, Shupack JL, Driller J, Rorke M, Lizzi F. Diagnostic high-resolution ultrasound in dermatology. Int Dermatol. 1993;32:243–50.
Scidenari S. High-frequency sonography combined with image analysis: a noninvasive objective method for skin evaluation and description. Clin Dermatol. 1995;13:349–59.
El Gammel S, El Gammel C, Kasper K, Picck C, Altmeyer P, Vogt M, Ermert H. Sonography of the skin at 100 MHz enables in vivo visualization of stratum corneum and viable epidermis in palmer skin and psoriatic plaques. J Invest Dermatol. 1999;113:821–9.
Saijo Y, Kobayashi K, Okada N, Hozumi N, Hagiwara Y, Tanaka A, Iwamoto T. High frequency ultrasound imaging of surface and subsurface structures of fingerprints. Conf Proc IEEE Eng Med Biol Soc. 2008;2008:2173–6.
Acknowledgments
This study was supported by a Grant-in-aid for scientific research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (No. 21500451). The authors are grateful to Mr. C.W.P. Reynolds of the Department of International Medical Communications, Tokyo Medical University, for his careful revision of the English in this manuscript.
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Fujii, Y., Yoshizawa, M., Emoto, R. et al. Processed skin surface images acquired by acoustic impedance difference imaging using the ultrasonic interference method: a pilot study. J Med Ultrasonics 39, 37–42 (2012). https://doi.org/10.1007/s10396-011-0334-7
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DOI: https://doi.org/10.1007/s10396-011-0334-7