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Determinants of Patient Satisfaction with Photodynamic Therapy for Neovascular Age-related Macular Degeneration or Polypoidal Choroidal Vasculopathy

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Abstract

Purpose

To evaluate the determinants of patient satisfaction with photodynamic therapy (PDT) for neovascular age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV).

Methods

Questionnaires were mailed to 69 patients who had undergone PDT for AMD or PCV at the Kobe City General Hospital. The questionnaire considered the following parameters: subjective change in visual acuity, subjective change in the relative scotoma in central vision, subjective change in visual distortion, and patient satisfaction with PDT scored on a 100-point scale.

Results

Nine patients (14%) reported their subjective visual acuity change as “significantly improved” and 21 (32%) as “slightly improved”; 18 (27%) reported “no change”; 12 (18%) reported their visual acuity as “slightly worsened”; and 6 (9%) as “significantly worsened.” Subjective change in the central scotoma was reported improved in 43 patients (64%) and visual distortion had improved subjectively in 31 patients (47%). The satisfaction score was 59 ± 25 in patients who had undergone PDT for AMD and 75 ± 24 in those with PCV. Not only the visual acuity change but also the subjective change in central scotoma and visual distortion correlated significantly with the satisfaction score.

Conclusions

More patients who have undergone PDT for AMD or PCV perceive improvement in central scotoma and visual distortion than in visual acuity. Since these subjective changes correlated significantly with the satisfaction score, subjective change in central scotoma and visual distortion, in addition to visual acuity, should be taken into account in evaluating the benefits of PDT. Jpn J Ophthalmol 2007;51:368–374 © Japanese Ophthalmological Society 2007

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References

  1. LA Yannuzzi J Sorenson RF Spaide B Lipson (1990) ArticleTitleIdiopathic polypoidal choroidal vasculopathy (IPCV) Retina 10 1–8 Occurrence Handle1:STN:280:DyaK3c3mtVequw%3D%3D Occurrence Handle10.1097/00006982-199001010-00001 Occurrence Handle1693009

    Article  CAS  PubMed  Google Scholar 

  2. LA Yannuzzi DW Wong BS Sforzolini et al. (1999) ArticleTitlePolypoidal choroidal vasculopathy and neovascularized age-related macular degeneration Arch Ophthalmol 117 1503–1510 Occurrence Handle1:STN:280:DC%2BD3c%2FivFanuw%3D%3D Occurrence Handle10.1001/archopht.117.11.1503 Occurrence Handle10565519

    Article  CAS  PubMed  Google Scholar 

  3. Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials—TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group. Arch Ophthalmol 1999;117:1329–1345

  4. NM Bressler (2001) ArticleTitlePhotodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: two-year results of two randomized clinical trials—TAP report 2 Arch Ophthalmol 119 198–207 Occurrence Handle1:CAS:528:DC%2BD3MXhsVCkurs%3D Occurrence Handle11176980

    CAS  PubMed  Google Scholar 

  5. Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization—verteporfin in photodynamic therapy report 2. Am J Ophthalmol 2001;131:541–560

  6. M Quaranta M Mauget-Faysse G Coscas (2002) ArticleTitleExudative idiopathic polypoidal choroidal vasculopathy and photodynamic therapy with verteporfin Am J Ophthalmol 134 277–280 Occurrence Handle10.1016/S0002-9394(02)01516-7 Occurrence Handle12140043

    Article  PubMed  Google Scholar 

  7. RF Spaide I Donsoff DL Lam et al. (2002) ArticleTitleTreatment of polypoidal choroidal vasculopathy with photodynamic therapy Retina 22 529–535 Occurrence Handle10.1097/00006982-200210000-00001 Occurrence Handle12441716

    Article  PubMed  Google Scholar 

  8. WM Chan DS Lam TY Lai et al. (2004) ArticleTitlePhotodynamic therapy with verteporfin for symptomatic polypoidal choroidal vasculopathy: one-year results of a prospective case series Ophthalmology 111 1576–1584 Occurrence Handle10.1016/j.ophtha.2003.12.056 Occurrence Handle15288991

    Article  PubMed  Google Scholar 

  9. UM Schmidt-Erfurth H Elsner N Terai A Benecke G Dahmen SM Michels (2004) ArticleTitleEffects of verteporfin therapy on central visual field function Ophthalmology 111 931–939 Occurrence Handle10.1016/j.ophtha.2003.12.025 Occurrence Handle15121371

    Article  PubMed  Google Scholar 

  10. AM Armbrecht PA Aspinall B Dillon (2004) ArticleTitleA prospective study of visual function and quality of life following PDT in patients with wet age-related macular degeneration Br J Ophthalmol 88 1270–1273 Occurrence Handle1:STN:280:DC%2BD2cvms12lsg%3D%3D Occurrence Handle10.1136/bjo.2003.038604 Occurrence Handle15377549 Occurrence Handle1772343

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. I Krebs S Binder U Stolba S Brunner (2004) ArticleTitleReading ability and central visual field after photodynamic therapy Ophthalmologica 218 185–192 Occurrence Handle10.1159/000076843 Occurrence Handle15103215

    Article  PubMed  Google Scholar 

  12. CH Meyer DJ Lapolice S Fekrat (2005) ArticleTitleFunctional changes after photodynamic therapy with verteporfin Am J Ophthalmol 139 214–215 Occurrence Handle10.1016/j.ajo.2004.07.034 Occurrence Handle15652863

    Article  PubMed  Google Scholar 

  13. F Krummenauer M Braun HB Dick (2005) ArticleTitleClinical outcome and subjective quality of life after photodynamic therapy in patients with age-related macular degeneration Eur J Ophthalmol 15 74–80 Occurrence Handle1:STN:280:DC%2BD2M7itVOlsA%3D%3D Occurrence Handle10.1177/112067210501500112 Occurrence Handle15751243

    Article  CAS  PubMed  Google Scholar 

  14. Hewitt AW, Jeganathan VS, Kidd JE, Pesudovs K, Verma N. Influence of photodynamic therapy for age-related macular degeneration upon subjective vision related quality of life. Graefes Arch Clin Exp Ophthalmol 2006:1–6

  15. L Arias O Pujol J Berniell et al. (2005) ArticleTitleImpact of lesion size on photodynamic therapy with verteporfin of predominantly classic lesions in age-related macular degeneration Br J Ophthalmol 89 312–315 Occurrence Handle1:STN:280:DC%2BD2M7hs1Onug%3D%3D Occurrence Handle10.1136/bjo.2004.050997 Occurrence Handle15722311 Occurrence Handle1772570

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. H Imai S Honda Y Nakanishi H Yamamoto Y Tsukahara A Negi (2006) ArticleTitleDifferent transitions of multifocal electroretinogram recordings between patients with age-related macular degeneration and polypoidal choroidal vasculopathy after photodynamic therapy Br J Ophthalmol 90 1524–1530 Occurrence Handle1:STN:280:DC%2BD28nnsVyiug%3D%3D Occurrence Handle10.1136/bjo.2006.092783 Occurrence Handle16825279 Occurrence Handle1857528

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. RM Silva J Figueira ML Cachulo L Duarte JR Faria de Abreu JG Cunha-Vaz (2005) ArticleTitlePolypoidal choroidal vasculopathy and photodynamic therapy with verteporfin Graefes Arch Clin Exp Ophthalmol 243 973–979 Occurrence Handle1:CAS:528:DC%2BD2MXhtFart7fN Occurrence Handle10.1007/s00417-005-1139-4 Occurrence Handle15864616

    Article  CAS  PubMed  Google Scholar 

  18. N Hussain A Hussain S Natarajan (2005) ArticleTitleRole of photodynamic therapy in polypoidal choroidal vasculopathy Indian J Ophthalmol 53 101–104 Occurrence Handle10.4103/0301-4738.16172 Occurrence Handle15976464

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, Kobe City General Hospital, Kobe, Japan

    Kenji Yamashiro, Akihiro Nishida & Yasuo Kurimoto

  2. Department of Regenerative Medicine, Institute of Biomedical Research and Innovation, Kobe, Japan

    Kenji Yamashiro, Akihiro Nishida & Yasuo Kurimoto

  3. Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

    Akitaka Tsujikawa

Authors
  1. Kenji Yamashiro
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  2. Akitaka Tsujikawa
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  3. Akihiro Nishida
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  4. Yasuo Kurimoto
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Correspondence to Kenji Yamashiro.

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Yamashiro, K., Tsujikawa, A., Nishida, A. et al. Determinants of Patient Satisfaction with Photodynamic Therapy for Neovascular Age-related Macular Degeneration or Polypoidal Choroidal Vasculopathy. Jpn J Ophthalmol 51, 368–374 (2007). https://doi.org/10.1007/s10384-007-0465-y

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  • DOI: https://doi.org/10.1007/s10384-007-0465-y

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