Skip to main content

Advertisement

SpringerLink
Log in

Longitudinal Changes in Corneal Irregular Astigmatism and Visual Acuity in Eyes with Keratoconus

  • CLINICAL INVESTIGATION
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To quantitatively investigate the time course of changes in corneal irregular astigmatism and their relation to best spectacle-corrected visual acuity (BSCVA) in eyes with keratoconus.

Methods

Subjects were 47 patients (57 eyes) with keratoconus who had undergone videokeratography examinations at least twice, with an interval of 1 year or longer between each examination. By means of Fourier series harmonic analysis, topography data were separated into spherical component, regular astigmatism, asymmetry, and higher order irregularity.

Results

In eyes that showed apparent progression on color-coded maps, the yearly rate of change was significantly positive for spherical component (P = 0.03) and higher order irregularity (P = 0.006). In eyes with apparent progression, the yearly change rate of BSCVA was significantly positive (P = 0.001), but not in the eyes without apparent progression (P = 0.1655). In eyes with progression on maps, the yearly change rate of BSCVA was significantly correlated with the change rate of higher order irregularity per year (r = 0.770, P = 0.0004).

Conclusions

The results indicated that progression of keratoconus is associated with deterioration of BSCVA, which is in turn significantly correlated with increases in corneal higher order irregularity. Jpn J Ophthalmol 2007;51:265–269 @ Japanese Ophthalmological Society 2007

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. JH Krachmer RS Feder MQ Belin (1984) ArticleTitleKeratoconus and related noninflammatory corneal thinning disorders Surv Ophthalmol 28 293–322 Occurrence Handle6230745 Occurrence Handle10.1016/0039-6257(84)90094-8 Occurrence Handle1:STN:280:BiuC2cjkslY%3D

    Article  PubMed  CAS  Google Scholar 

  2. YS Rabinowitz (1998) ArticleTitleKeratoconus Surv Ophthalmol 42 297–319 Occurrence Handle9493273 Occurrence Handle10.1016/S0039-6257(97)00119-7 Occurrence Handle1:STN:280:DyaK1c7lsVehtg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  3. RS Feder P Kshettry (2005) Noninflammatory ecstatic disorders JH Krachmer MJ Mannis EJ Holland (Eds) Cornea, 2nd ed Elsevier Mosby Philadelphia

    Google Scholar 

  4. LJ Maguire JC Lowry (1991) ArticleTitleIdentifying progression of subclinical keratoconus by serial topography analysis Am J Ophthalmol 112 41–45 Occurrence Handle1882920 Occurrence Handle1:STN:280:By6A2Mzmsl0%3D

    PubMed  CAS  Google Scholar 

  5. MK Smolek SD Klyce N Maeda (1994) ArticleTitleKeratoconus and contact lens-induced corneal warpage analysis using the keratomorphic diagram Invest Ophthalmol Vis Sci 35 4192–4204 Occurrence Handle8002240 Occurrence Handle1:STN:280:ByqD1Mrltl0%3D

    PubMed  CAS  Google Scholar 

  6. MK Smolek SD Klyce (1997) ArticleTitleCinemakeratography using computer morphing Optom Vis Sci 74 970–975 Occurrence Handle9403893 Occurrence Handle10.1097/00006324-199711000-00030 Occurrence Handle1:STN:280:DyaK1c%2FmslKksw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  7. T Oshika T Tanabe A Tomidokoro S Amano (2002) ArticleTitleProgression of keratoconus assessed by Fourier analysis of videokeratography data Ophthalmology 109 339–342 Occurrence Handle11825821 Occurrence Handle10.1016/S0161-6420(01)00903-4

    Article  PubMed  Google Scholar 

  8. LJ Maguire (1998) Ectatic corneal degenerations HE Kaufman BA Barron MB McDonald (Eds) The cornea, 2nd ed Butterworth-Heinemann Boston

    Google Scholar 

  9. JO Hjortdal L Erdmann T Bek (1995) ArticleTitleFourier analysis of video-keratographic data. A tool for separation of spherical, regular astigmatic and irregular astigmatic corneal power components Ophthalmic Physiol Opt 15 171–185 Occurrence Handle7659417 Occurrence Handle1:STN:280:ByqA1cfktVM%3D

    PubMed  CAS  Google Scholar 

  10. TW Raasch (1995) ArticleTitleCorneal topography and irregular astigmatism Optom Vis Sci 72 809–815 Occurrence Handle8587769 Occurrence Handle10.1097/00006324-199511000-00006 Occurrence Handle1:STN:280:BymC283nt1E%3D

    Article  PubMed  CAS  Google Scholar 

  11. T Olsen M Dam-Johansen T Bek JO Hjortdal (1996) ArticleTitleEvaluating surgically induced astigmatism by Fourier analysis of corneal topography data J Cataract Refract Surg 22 318–323 Occurrence Handle8778364 Occurrence Handle1:STN:280:BymB2s3nvVA%3D

    PubMed  CAS  Google Scholar 

  12. T Oshika A Tomidokoro K Maruo T Tokunaga N Miyata (1998) ArticleTitleQuantitative evaluation of irregular astigmatism by Fourier series harmonic analysis of videokeratography data Invest Ophthalmol Vis Sci 39 705–709 Occurrence Handle9538876 Occurrence Handle1:STN:280:DyaK1c7pvFOjsA%3D%3D

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan

    Mariko Suzuki, Shiro Amano, Norihiko Honda, Tomohiko Usui & Satoru Yamagami

  2. Department of Ophthalmology, University of Tsukuba Graduate School of Medicine, Tsukuba, Ibaraki, Japan

    Tetsuro Oshika

Authors
  1. Mariko Suzuki
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shiro Amano
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Norihiko Honda
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Tomohiko Usui
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Satoru Yamagami
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Tetsuro Oshika
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shiro Amano.

About this article

Cite this article

Suzuki, M., Amano, S., Honda, N. et al. Longitudinal Changes in Corneal Irregular Astigmatism and Visual Acuity in Eyes with Keratoconus. Jpn J Ophthalmol 51, 265–269 (2007). https://doi.org/10.1007/s10384-007-0453-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10384-007-0453-2

Key words

Search

Navigation