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Case of Optic Nerve Involvement in Metastasis of a Gastrointestinal Stromal Tumor

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Background

The gastrointestinal stromal tumor (GIST) belongs to the leiomyosarcoma or leiomyoma group, and metastasis of leiomyosarcoma to the orbit is extremely rare. The most common sign of the metastasis of leiomyosarcoma to the orbit is proptosis; the primary lesion is usually found in skin or soft tissue.

Case

A 60-year-old man, who had a history of multiple metastases of GIST, suffered sudden unilateral blindness.

Observations

His history and computed tomographic scans suggested that the lesion was a metastasis of GIST to the cavernous sinus around the root of the optic nerve.

Conclusion

To the best of our knowledge, this is the first case of metastasis of GIST to the orbit. Jpn J Ophthalmol 2004;48:166–168 © Japanese Ophthalmological Society 2004

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Authors and Affiliations

  1. Division of Ophthalmology, Tokyo Metropolitan Geriatric Center, Tokyo, Japan

    Kazuhide Akiyama, Jiro Numaga & Nobuyuki Koseki

  2. Division of Ophthalmology, Misato Junshin General Hospital, Saitama, Japan

    Fumie Kagaya

  3. Department of Pathology, School of Medicine, The University of Tokyo, Tokyo, Japan

    Yutaka Takazawa

  4. Division of Ophthalmology, National Cancer Center Hospital, Tokyo, Japan

    Shigenobu Suzuki

  5. Department of Ophthalmology, School of Medicine, The University of Tokyo, Tokyo, Japan

    Satoshi Kato & Toshikatsu Kaburaki

  6. Division of Ophthalmology, Saitama Red Cross Hospital, Saitama, Japan

    Hidetoshi Kawashima

Authors
  1. Kazuhide Akiyama
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  2. Jiro Numaga
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  3. Fumie Kagaya
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  4. Yutaka Takazawa
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  5. Shigenobu Suzuki
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  6. Nobuyuki Koseki
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  7. Satoshi Kato
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  8. Toshikatsu Kaburaki
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  9. Hidetoshi Kawashima
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Corresponding author

Correspondence to Kazuhide Akiyama.

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Cite this article

Akiyama, K., Numaga, J., Kagaya, F. et al. Case of Optic Nerve Involvement in Metastasis of a Gastrointestinal Stromal Tumor. Jpn J Ophthalmol 48, 166–168 (2004). https://doi.org/10.1007/s10384-003-0028-9

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  • DOI: https://doi.org/10.1007/s10384-003-0028-9

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