Zusammenfassung
Die Schafgarbe (Achillea millefolium L. s.l.) wird traditionell bei krampfartigen und entzündlichen Magen-Darm-Erkrankungen, als Gallenmittel und äußerlich bei Entzündungen eingesetzt. In neuesten Untersuchungen konnte gezeigt werden, dass die Flavonoide aus der Schafgarbe spasmolytisch wirken, während die Dicaffeoylchinasäuren choleretisch aktiv sind. Außerdem wurde eine in vitro-Hemmung der humanen neutrophilen Elastase, einer am Entzündungsgeschehen beteiligten Protease, durch Extrakte und Fraktionen aus der Schafgarbe beobachtet, was einen zusätzlichen Hinweis zur antiphlogistischen Wirkweise von Achillea millefolium L. s.l. darstellt. Somit bestätigen diese Ergebnisse die volksmedizinische Anwendung der Droge.
Summary
Yarrow (Achillea millefolium L. s.l.) is traditionally used in the treatment of inflammatory and spasmodic gastro-intestinal disorders, hepato-biliary complaints and inflammation. Now we could show that the flavonoids mediated the antispasmodic properties of yarrow, whereas the dicaffeoylquinic acids caused the choleretic effects. Moreover, we observed an in vitro-inhibition of human neutrophil elastase, a protease involved in the inflammatory process, by extracts and fractions from yarrow, which suggests additional mechanisms of antiphlogistic action. The presented results confirm the traditional use of yarrow.
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Benedek, B., Kopp, B. Achillea millefolium L. s.l. revisited: Recent findings confirm the traditional use. Wien Med Wochenschr 157, 312–314 (2007). https://doi.org/10.1007/s10354-007-0431-9
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DOI: https://doi.org/10.1007/s10354-007-0431-9