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Value of a Protective Stoma in Low Anterior Resections for Rectal Cancer

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Diseases of the Colon & Rectum

Abstract

INTRODUCTION: Anastomotic leakage is a major problem in colorectal surgery and in particular in operations for low rectal cancer. The present study investigates the question whether a protective stoma can reduce the (clinical and radiologic) anastomotic leakage rate and/or the rate of leakage requiring surgery. METHODS: The investigation took the form of a prospective multicenter study involving 75 German hospitals and was performed between January 1, 1999, and December 31, 1999. A comparison was made of the postoperative results of procedures performed with and those performed without a protective stoma in patients undergoing low anterior rectal resection. In addition, logistic regression using the target criteria, overall anastomotic leakage and anastomotic leakage requiring surgery, was applied. RESULTS: Among the 3,695 operations performed for carcinoma of the rectum or colon, 482 were low anterior resections. In 334 patients (69.3 percent) no protective stoma was constructed, whereas 148 (30.7 percent) received such protection. Age, American Society of Anesthesiologists physical status, and body mass index were identical in both groups. In the group receiving a protective stoma, however, neoadjuvant radiochemotherapy was more common, the tumors were lower—and thus the total mesorectal excision rate higher, the intraoperative complication rate was higher, and the duration of the operation was longer. The differences were all significant. The major criterion (overall anastomotic leakage rate) was identical in the two groups, but the rate of leakage requiring surgery was significantly lower in patients receiving a protective stoma (P = 0.028). The logistic regression revealed that use of a protective stoma is a predictor of protection against anastomotic leakage requiring surgery. The distance of the tumor from the anal verge and the duration of the operation are further predictors. CONCLUSION: The particular benefit of a covering stoma is reduction in the rate of leaks requiring surgery and thus in the severe consequences of an anastomotic leakage.

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Authors and Affiliations

  1. Institute for Quality Management in Operative Medicine at the Otto-von-Guericke University, Magdeburg, Germany

    Frank Marusch Ph.D., Andreas Koch M.D., Uwe Schmidt M.D., Sven Geiβler M.D., Henning Dralle Ph.D., Hans-Detlev Saeger Ph.D., Stefanie Wolff M.D., Gerd Nestler M.D., Matthias Pross Ph.D., Ingo Gastinger Ph.D. & Hans Lippert Ph.D.

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  1. Frank Marusch Ph.D.
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  2. Andreas Koch M.D.
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  3. Uwe Schmidt M.D.
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  4. Sven Geiβler M.D.
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  5. Henning Dralle Ph.D.
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  7. Stefanie Wolff M.D.
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  8. Gerd Nestler M.D.
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  9. Matthias Pross Ph.D.
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  11. Hans Lippert Ph.D.
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Marusch, F., Koch, A., Schmidt, U. et al. Value of a Protective Stoma in Low Anterior Resections for Rectal Cancer. Dis Colon Rectum 45, 1164–1171 (2002). https://doi.org/10.1007/s10350-004-6384-9

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  • DOI: https://doi.org/10.1007/s10350-004-6384-9

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